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View Structure Prediction Details

Protein: gi|62656892, gi|...
Organism: Rattus norvegicus
Length: 224 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|62656892, gi|....

Description E-value Query
Range
Subject
Range
gi|4322076 - gi|4322076|gb|AAD15947.1| homeobox protein [Danio rerio]
163.0 [0..1] [213..1]
gi|109114187, gi... - gi|109114187|ref|XP_001088485.1| PREDICTED: similar to homeobox B6 isoform 3 [Macaca mulatta], gi|10...
162.0 [0..1] [224..1]
gi|60654293 - gi|60654293|gb|AAX29839.1| homeobox B6 [synthetic construct]
159.0 [0..1] [224..1]
gi|148226630, gi... - gi|148226630|ref|NP_001090379.1| homeo box B6 [Xenopus laevis], gi|116063408|gb|AAI23271.1| Hoxb6 pr...
159.0 [0..1] [224..1]
gi|123979658, gi... - gi|61363527|gb|AAX42406.1| homeobox B6 [synthetic construct], gi|208968501|dbj|BAG74089.1| homeobox ...
HOXB6 - homeobox B6
gi|114666346, gi... - gi|114666348|ref|XP_001172980.1| PREDICTED: homeobox B6 isoform 3 [Pan troglodytes], gi|114666346|re...
158.0 [0..1] [224..1]
gi|73966244, gi|... - gi|73966244|ref|XP_864710.1| PREDICTED: similar to Homeobox protein Hox-B6 (Hox-2.2) (MH-22A) isofor...
158.0 [0..1] [224..1]
gi|76644498, gi|... - gi|76644500|ref|XP_887495.1| PREDICTED: similar to Homeobox protein Hox-B6 (Hox-2.2) (MH-22A) isofor...
157.0 [0..1] [211..1]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYFVNSTF PVTLASGQES FLGQLPLYSS GYADPLRHYP APYGPGPGQD KGFAASSYYP  60
   61 PAGGGYGRAA PCDYGPAPAF YREKDAACAL SGADEPPPFH PEPRKSDCAQ DKSVFGETEE 120
  121 QKC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.235 0.006 pattern specification process c.16.1 Lumazine synthase

Predicted Domain #2
Region A:
Residues: [124-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STPVYPWMQR MNSCNSSSFG PSGRRGRQTY TRYQTLELEK EFHYNRYLTR RRRIEIAHAL  60
   61 CLTERQIKIW FQNRRMKWKK ESKLLSASQL SAEEEEEKPA E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.30103
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle