YRC Public Data Repository - Protein Structure Prediction

Protein:	HXC8_RAT
Organism:	Rattus norvegicus
Length:	108 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXC8_RAT.

Description	E-value	Query Range	Subject Range
HXA7_MOUSE - Homeobox protein Hox-A7 OS=Mus musculus GN=Hoxa7 PE=2 SV=2	122.0	[0..5]	[100..119]
gi\|34398398 - gi\|34398398\|gb\|AAQ67266.1\| antennapedia [Drosophila virilis]	121.0	[0..2]	[96..286]
gi\|158711670, gi... - gi\|62647267\|ref\|XP_575478.1\| PREDICTED: similar to Hoxa7 [Rattus norvegicus], gi\|158711670\|ref\|NP_00...	121.0	[0..5]	[100..119]
ANTP_DROSU - Homeotic protein antennapedia OS=Drosophila subobscura GN=Antp PE=3 SV=1	119.0	[0..2]	[96..300]
gi\|15425738, gi\|... - gi\|15425738\|dbj\|BAB64346.1\| homeotic protein [Daphnia magna], gi\|109944931\|dbj\|BAE96993.1\| Antennape...	119.0	[0..2]	[77..533]
Antp-PL, Antp-PJ... - The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is...	118.0	[0..2]	[96..284]
HXD4_PANPA - Homeobox protein Hox-D4 OS=Pan paniscus GN=HOXD4 PE=3 SV=1 HXD4_PANTR - Homeobox protein Hox-D4 OS=Pan troglodytes GN=HOXD4 PE=3 SV=1	117.0	[0..2]	[108..141]
gi\|72235, gi\|296... - pir\|\|WJHU4B homeotic protein Hox D4 - human, gi\|296652\|emb\|CAA35237.1\| hox 5.1 protein [Homo sapien... gi\|208968521 - gi\|208968521\|dbj\|BAG74099.1\| homeobox D4 [synthetic construct]	117.0	[0..2]	[108..141]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHNQTGVLFC SAPGRRSGRQ TYSRYQTLEL EKEFLFNPYL TRKRRIEVSH ALGLTERQVK  60
   61 IWFQNRRMKW KKENNKDKLP GARDEEKVEE EGNEEEEKEE EEKEENKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	1pufA
Description:	Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.334577365229545	bayes_pls_golite062009
transcription regulator activity	0.0696342306231097	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: