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Protein Overview: Antp-PL, Antp-PJ...

General Information:
Name(s) found: Antp-PJ / FBpp0089246 [FlyBase]
Antp-PI / FBpp0089245 [FlyBase]
Antp-PL / FBpp0081162 [FlyBase]
Antp-PM / FBpp0081161 [FlyBase]
Description(s) found:
Found 70 descriptions.
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  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA][NAS]
    Biological Process: heart development [IEP]
    midgut development [TAS]
    lymph gland development [IMP]
    specification of segmental identity, antennal segment [IMP]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA]
    segment specification [NAS]
    regulation of transcription from RNA polymerase II promoter [NAS]
    Molecular Function: transcription factor activity [IEA]
    specific RNA polymerase II transcription factor activity [NAS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMSTNNCES MTSYFTNSYM GADMHHGHYP GNGVTDLDAQ QMHHYSQNAN HQGNMPYPRF  60
   61 PPYDRMPYYN GQGMDQQQQH QVYSRPDSPS SQVGGVMPQA QTNGQLGVPQ QQQQQQQQPS 120
  121 QNQQQQQAQQ APQQLQQQLP QVTQQVTHPQ QQQQQPVVYA SCKLQAAVGG LGMVPEGGSP 180
  181 PLVDQMSGHH MNAQMTLPHH MGHPQAQLGY TDVGVPDVTE VHQNHHNMGM YQQQSGVPPV 240
  241 GAPPQGMMHQ GQGPPQMHQG HPGQHTPPSQ NPNSQSSGMP SPLYPWMRSQ FGKCQERKRG 300
  301 RQTYTRYQTL ELEKEFHFNR YLTRRRRIEI AHALCLTERQ IKIWFQNRRM KWKKENKTKG 360
  361 EPGSGGEGDE ITPPNSPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] PSI-BLAST 3.221849 Sec24
    2 View Details [235..295] deduced N/A No confident structure predictions are available.
    3 View Details [296..378] PSI-BLAST 24.39794 DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle