YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|124526477, gi...
Organism:	Escherichia coli B
Length:	505 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124526477, gi....

Description	E-value	Query Range	Subject Range
gi\|115513626, gi... - gi\|117624502\|ref\|YP_853415.1\| amidophosphoribosyltransferase [Escherichia coli APEC O1], gi\|11551362... gi\|187771012, gi... - gi\|187771012\|gb\|EDU34856.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4196], g... gi\|91073182, gi\|... - gi\|91211608\|ref\|YP_541594.1\| amidophosphoribosyltransferase [Escherichia coli UTI89], gi\|91073182\|gb... gi\|168767942, gi... - gi\|189362890\|gb\|EDU81309.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4486], g... gi\|15832450, gi\|... - gi\|15832450\|ref\|NP_311223.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. Sakai], g... gi\|189372889, gi... - gi\|189372889\|gb\|EDU91305.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC869], gi... gi\|110642516, gi... - gi\|110642516\|ref\|YP_670246.1\| amidophosphoribosyltransferase [Escherichia coli 536], gi\|110344108\|gb... gi\|168780171, gi... - gi\|189001887\|gb\|EDU70873.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4076], g... gi\|195935691 - gi\|195935691\|ref\|ZP_03081073.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4024... gi\|189378916, gi... - gi\|189378916\|gb\|EDU97332.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC508], gi... gi\|208813534, gi... - gi\|208813534\|ref\|ZP_03254863.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4045... gi\|208809191, gi... - gi\|208809191\|ref\|ZP_03251528.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4206... gi\|188017294, gi... - gi\|188017294\|gb\|EDU55416.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4113], g... gi\|189368340, gi... - gi\|189368340\|gb\|EDU86756.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501], g... gi\|168755068, gi... - gi\|189357748\|gb\|EDU76167.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4401], g... gi\|83570132, gi\|... - gi\|83570132\|ref\|ZP_00921579.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Shig... gi\|75243123, gi\|... - gi\|75243123\|ref\|ZP_00726829.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|227887370, gi... - gi\|227887370\|ref\|ZP_04005175.1\| amidophosphoribosyltransferase [Escherichia coli 83972], gi\|22783572... gi\|188495078, gi... - gi\|75515677\|ref\|ZP_00737812.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|254794205, gi... - gi\|254794205\|ref\|YP_003079042.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. TW143... gi\|209158630, gi... - gi\|209397230\|ref\|YP_002271721.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC411... gi\|208821678, gi... - gi\|208821678\|ref\|ZP_03261998.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4042... gi\|217327559, gi... - gi\|217327559\|ref\|ZP_03443642.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. TW1458... gi\|215265597, gi... - gi\|215487525\|ref\|YP_002329956.1\| amidophosphoribosyltransferase [Escherichia coli O127:H6 str. E2348... gi\|218690472, gi... - gi\|218690472\|ref\|YP_002398684.1\| amidophosphoribosyltransferase [Escherichia coli ED1a], gi\|21842803... gi\|218365994, gi... - gi\|218559225\|ref\|YP_002392138.1\| amidophosphoribosyltransferase [Escherichia coli S88], gi\|218365994... gi\|218432939, gi... - gi\|218705842\|ref\|YP_002413361.1\| amidophosphoribosyltransferase [Escherichia coli UMN026], gi\|218432... gi\|218370774, gi... - gi\|218700788\|ref\|YP_002408417.1\| amidophosphoribosyltransferase [Escherichia coli IAI39], gi\|2183707... gi\|26248700, gi\|... - gi\|26248700\|ref\|NP_754740.1\| amidophosphoribosyltransferase [Escherichia coli CFT073], gi\|26109105\|g... gi\|209764850, gi... - pir\|\|E85872 amidophosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|12516671, gi\|... - gi\|15802859\|ref\|NP_288886.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 EDL933], gi\|12... gi\|15832450, gi\|... - gi\|15832450\|ref\|NP_311223.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7], gi\|13362666\|...	528.0	[0..1]	[505..1]
gi\|81246204, gi\|... - gi\|82544793\|ref\|YP_408740.1\| amidophosphoribosyltransferase [Shigella boydii Sb227], gi\|81246204\|gb\|...	528.0	[0..1]	[505..1]
gi\|157161800, gi... - gi\|75196355\|ref\|ZP_00706425.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch...	527.0	[0..1]	[505..1]
gi\|42593 - gi\|42593\|emb\|CAA30971.1\| amidophosphoribosyltransferase [Escherichia coli]	527.0	[0..1]	[505..1]
gi\|81241871, gi\|... - gi\|82777723\|ref\|YP_404072.1\| amidophosphoribosyltransferase [Shigella dysenteriae Sd197], gi\|8124187...	527.0	[0..1]	[505..1]
gi\|110806277, gi... - gi\|110806277\|ref\|YP_689797.1\| amidophosphoribosyltransferase [Shigella flexneri 5 str. 8401], gi\|110...	526.0	[0..1]	[505..1]
gi\|238718693, gi... - gi\|77960842\|ref\|ZP_00824697.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Yers...	525.0	[0..1]	[505..1]
gi\|224583149, gi... - gi\|224583149\|ref\|YP_002636947.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|206709583, gi... - gi\|207857780\|ref\|YP_002244431.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205273256, gi... - gi\|205353475\|ref\|YP_002227276.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|204321519, gi... - gi\|204928975\|ref\|ZP_03220118.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|199605838, gi... - gi\|200388740\|ref\|ZP_03215352.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|198242494, gi... - gi\|198242494\|ref\|YP_002216435.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197361675, gi... - gi\|197361675\|ref\|YP_002141311.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197262622, gi... - gi\|197262622\|ref\|ZP_03162696.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|197212987, gi... - gi\|197249284\|ref\|YP_002147323.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|62128567, gi\|... - gi\|62180934\|ref\|YP_217351.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194734420, gi... - gi\|194734420\|ref\|YP_002115433.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|194471463, gi... - gi\|194471463\|ref\|ZP_03077447.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|194409186, gi... - gi\|194450882\|ref\|YP_002046418.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|56126998, gi\|... - gi\|56412741\|ref\|YP_149816.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194444570, gi... - gi\|194444570\|ref\|YP_002041626.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205344727, gi... - gi\|205344727\|gb\|EDZ31491.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168465927, gi... - gi\|195631420\|gb\|EDX49980.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205349326, gi... - gi\|205349326\|gb\|EDZ35957.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205338382, gi... - gi\|205338382\|gb\|EDZ25146.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|197289640, gi... - gi\|197289640\|gb\|EDY29003.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168229738, gi... - gi\|205335611\|gb\|EDZ22375.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|161612903, gi... - gi\|161612903\|ref\|YP_001586868.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|238912359 - gi\|238912359\|ref\|ZP_04656196.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ...	524.0	[0..1]	[505..1]
gi\|213852683 - gi\|213852683\|ref\|ZP_03382215.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|16761287 - gi\|16761287\|ref\|NP_456904.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|213426983 - gi\|213426983\|ref\|ZP_03359733.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213161329 - gi\|213161329\|ref\|ZP_03347039.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213646795 - gi\|213646795\|ref\|ZP_03376848.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213582920 - gi\|213582920\|ref\|ZP_03364746.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|25286956, gi\|... - gi\|25286956\|pir\|\|AH0801 amidophosphoribosyltransferase (EC 2.4.2.14) [imported] - Salmonella enteric... gi\|29141017, gi\|... - gi\|29141017\|ref\|NP_804359.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser...	524.0	[0..1]	[505..1]

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Predicted Domain #1

Region A:
Residues: [1-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIVGIAGV MPVNQSIYDA LTVLQHRGQD AAGIITIDAN NCFRLRKANG LVSDVFEARH  60
   61 MQRLQGNMGI GHVRYPTAGS SSASEAQPFY VNSPYGITLA HNGNLTNAHE LRKKLFEEKR 120
  121 RHINTTSDSE ILLNIFASEL DNFRHYPLEA DNIFAAIAAT NRLIRGAYAC VAMIIGHGMV 180
  181 AFRDPNGIRP LVLGKRDIDE NRTEYMVASE SVALDTLGFD FLRDVAPGEA IYITEEGQLF 240
  241 TRQCADNPVS NPCLFEYVYF ARPDSFIDKI SVYSARVNMG TKLGEKIARE WEDLDIDVVI 300
  301 PIPETSCDIA LEIARILGKP YRQGFVKNRY VGRTFIMPGQ QLRRKSVRRK LNANRAEFRD 360
  361 KNVLLVDDSI VRGTTSEQII EMAREAGAKK VYLASAAPEI RFPNVYGIDM PSATELIAHG 420
  421 REVDEIRQII GADGLIFQDL NDLIDAVRAE NPDIQQFECS VFNGVYVTKD VDQGYLDFLD 480
  481 TLRNDDAKAV QRQNEVENLE MHNEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	149.0
Match:	1ecbA
Description:	Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	0.985266832225609	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	0.625087274084001	bayes_pls_golite062009
nucleic acid binding	0.283725923623827	bayes_pls_golite062009
ligase activity	0.204093345072151	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009
endopeptidase activity	0.0940838340168359	bayes_pls_golite062009
peptidase activity	0.0898497842822991	bayes_pls_golite062009
transcription regulator activity	0.057753538747651	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.012663147802059	bayes_pls_golite062009
protein binding	0.00621436730716318	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: