YRC Public Data Repository - Protein Structure Prediction

Protein:	RPE_MOUSE
Organism:	Mus musculus
Length:	228 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPE_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|52078454, gi\|... - gi\|52078454\|gb\|AAH82474.1\| LOC494647 protein [Xenopus laevis], gi\|148230294\|ref\|NP_001087964.1\| hypo...	226.0	[0..1]	[228..1]
gi\|114583049 - gi\|114583049\|ref\|XP_001146078.1\| PREDICTED: ribulose-5-phosphate-3-epimerase isoform 9 [Pan troglody... RPE - ribulose-5-phosphate-3-epimerase gi\|190689795, gi... - gi\|190691163\|gb\|ACE87356.1\| ribulose-5-phosphate-3-epimerase protein [synthetic construct], gi\|19068... CCDS2388.1_1 - null gi\|109100810 - gi\|109100810\|ref\|XP_001109838.1\| PREDICTED: ribulose-5-phosphate-3-epimerase isoform 5 [Macaca mulat...	225.0	[0..1]	[228..1]
gi\|74005311 - gi\|74005311\|ref\|XP_536051.2\| PREDICTED: similar to Ribulose-phosphate 3-epimerase (Ribulose-5-phosph...	224.0	[0..1]	[228..1]
RPE_PONAB - Ribulose-phosphate 3-epimerase OS=Pongo abelii GN=RPE PE=2 SV=1 RPE_PONPY - Ribulose-phosphate 3-epimerase - Pongo pygmaeus (Orangutan)	222.0	[0..1]	[228..1]
gi\|114583053 - gi\|114583053\|ref\|XP_001145848.1\| PREDICTED: ribulose-5-phosphate-3-epimerase isoform 7 [Pan troglody... gi\|109100814 - gi\|109100814\|ref\|XP_001109744.1\| PREDICTED: ribulose-5-phosphate-3-epimerase isoform 3 [Macaca mulat...	221.0	[0..1]	[228..1]
gi\|74211763 - gi\|74211763\|dbj\|BAE29233.1\| unnamed protein product [Mus musculus]	220.0	[0..1]	[228..1]
gi\|12722019, gi\|... - gi\|15603484\|ref\|NP_246558.1\| ribulose-phosphate 3-epimerase [Pasteurella multocida subsp. multocida ...	219.0	[0..1]	[220..15]
gi\|55615453 - gi\|55615453\|ref\|XP_516061.1\| PREDICTED: ribulose-5-phosphate-3-epimerase isoform 10 [Pan troglodytes...	218.0	[0..1]	[228..1]
gi\|95767565 - gi\|95767565\|gb\|ABF57316.1\| ribulose-5-phosphate-3-epimerase [Bos taurus]	215.0	[0..9]	[228..1]

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Predicted Domain #1

Region A:
Residues: [1-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGCKIGPS ILNSDLANLG AECLRMLDSG ADYLHLDVMD GHFVPNITFG HPVVESLRKQ  60
   61 LGQDPFFDMH MMVSRPEQWV KPMAVAGANQ YTFHLEATEN PGALIKDIRE NGMKVGLAIK 120
  121 PGTTVEYLAP WANQIDMALV MTVEPGFGGQ KFMEDMMPKV HWLRTQFPTL DIEVDGGVGP 180
  181 DTVQKCAEAG ANMIVSGSAI MRSDDPRAVI NLLRNVCSEA AQKRSLDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1h1yA
Description:	D-ribulose-5-phosphate 3-epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribulose-phosphate 3-epimerase activity	3.28372503209224	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.86158562896415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.36492964250879	bayes_pls_golite062009
isomerase activity	0.935800409577999	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.764608070506109	bayes_pls_golite062009
orotidine-5'-phosphate decarboxylase activity	0.758594564254247	bayes_pls_golite062009
binding	0.595171555788202	bayes_pls_golite062009
racemase and epimerase activity	0.288948763149344	bayes_pls_golite062009
carboxy-lyase activity	0.1100847613283	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: