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View Structure Prediction Details

Protein: OTU6B_MOUSE
Organism: Mus musculus
Length: 294 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OTU6B_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109476175, gi... - gi|157820311|ref|NP_001100109.1| OTU domain containing 6B [Rattus norvegicus], gi|149045466|gb|EDL98...
257.0 [0..1] [294..32]
gi|57108027 - gi|57108027|ref|XP_544171.1| PREDICTED: similar to CG7857-PA [Canis familiaris]
256.0 [0..17] [294..115]
gi|74186199, gi|... - gi|74186368|dbj|BAE42955.1| unnamed protein product [Mus musculus], gi|74186199|dbj|BAE42895.1| unna...
246.0 [0..1] [294..1]
gi|76630286 - gi|76630286|ref|XP_874339.1| PREDICTED: similar to CG7857-PA [Bos taurus]
243.0 [0..1] [294..1]
gi|109086925 - gi|109086925|ref|XP_001086186.1| PREDICTED: similar to OTU domain containing 6B [Macaca mulatta]
237.0 [0..1] [294..1]
OTUD6B - OTU domain containing 6B
232.0 [0..1] [294..1]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEVVAEELD DEEQLVRRHR KEKKELQAKI QGMKNAVPKN DKKRRKQLTE DVAKLEREME  60
   61 QKHREELEQL KQLTFKDSKI DSVAVNISNL VLENQPPRIS KAQKRREKKA ALEKEREERI 120
  121 AEAEIENLSG ARHLESEKLA QILAARELEI KQIPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [156-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGHCMYGALE DQLREQDCAL TVASLRRQTA EYMQTHSDDF LPFLTNPSTG DMYTPEEFGK  60
   61 YCDDIVNTAA WGGQLELRAL SHILQTPIEI LQADAPPIIV GEEYPRNPLV LVYMRHAYGL 120
  121 GEHYNSVTRL VNSATENCS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.40148357876466 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.21949433847862 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
hydrolase activity 2.29464693834116 bayes_pls_golite062009
endopeptidase activity 2.26699762664334 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
binding 0.586727415287325 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.500110970732392 bayes_pls_golite062009
protein binding 0.130065210618838 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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