| Protein: | IL12A_MOUSE |
| Organism: | Mus musculus |
| Length: | 215 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL12A_MOUSE.
| Description | E-value | Query Range |
Subject Range |
|
|
355.0 | [0..23] | [215..345] |
|
|
354.0 | [0..1] | [215..35] |
|
|
350.0 | [0..1] | [215..1] |
|
|
347.0 | [0..1] | [215..1] |
|
|
346.0 | [0..1] | [215..1] |
|
|
346.0 | [0..1] | [215..35] |
|
Region A: Residues: [1-215] |
1 11 21 31 41 51
| | | | | |
1 MCQSRYLLFL ATLALLNHLS LARVIPVSGP ARCLSQSRNL LKTTDDMVKT AREKLKHYSC 60
61 TAEDIDHEDI TRDQTSTLKT CLPLELHKNE SCLATRETSS TTRGSCLPPQ KTSLMMTLCL 120
121 GSIYEDLKMY QTEFQAINAA LQNHNHQQII LDKGMLVAID ELMQSLNHNG ETLRQKPPVG 180
181 EADPYRVKMK LCILLHAFST RVVTINRVMG YLSSA
|
| Detection Method: |  |
| Confidence: | 92.69897 |
| Match: | 1f45B |
| Description: | Heterodimeric interleukin-12 alpha chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| interleukin-12 binding | 6.97623072079116 | bayes_pls_golite062009 |
| cytokine receptor binding | 6.47223189691244 | bayes_pls_golite062009 |
| interleukin-27 binding | 6.42738636095917 | bayes_pls_golite062009 |
| interleukin-12 beta subunit binding | 5.72528664872472 | bayes_pls_golite062009 |
| receptor binding | 5.3304255990112 | bayes_pls_golite062009 |
| cytokine activity | 5.22856893358132 | bayes_pls_golite062009 |
| growth factor activity | 4.92105782010612 | bayes_pls_golite062009 |
| interleukin-12 receptor binding | 4.74969286958651 | bayes_pls_golite062009 |
| protein binding | 3.26483713001551 | bayes_pls_golite062009 |
| binding | 2.48265117231403 | bayes_pls_golite062009 |
| prolactin receptor binding | 2.45721634350294 | bayes_pls_golite062009 |
| interleukin-6 receptor binding | 2.37535614986843 | bayes_pls_golite062009 |
| hormone activity | 2.25587306265428 | bayes_pls_golite062009 |
| growth hormone activity | 1.87531277315347 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 1.79326213321183 | bayes_pls_golite062009 |
| interleukin-2 receptor binding | 1.24568403220915 | bayes_pls_golite062009 |
| interleukin-10 receptor binding | 1.21666375770079 | bayes_pls_golite062009 |
| macrophage colony stimulating factor receptor binding | 1.01092937856314 | bayes_pls_golite062009 |
| interferon-alpha/beta receptor binding | 0.93290045827216 | bayes_pls_golite062009 |
| erythropoietin receptor binding | 0.77580300541347 | bayes_pls_golite062009 |
| transcription regulator activity | 0.486790888007408 | bayes_pls_golite062009 |
| catalytic activity | 0.246169290135575 | bayes_pls_golite062009 |
