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Protein Overview: gi|85397861, gi|...

General Information:
Name(s) found: gi|85397861 [NCBI NR]
gi|85397858 [NCBI NR]
gi|5923853 [NCBI NR]
gi|4323579 [NCBI NR]
gi|24430219 [NCBI NR]
gi|189234 [NCBI NR]
gi|119599062 [NCBI NR]
gi|1082548 [NCBI NR]
Description(s) found:
Found 32 descriptions.
SHOW ALL
  • gi|85397861|gb|AAI04985.1| Interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [Homo sapiens] [NCBI NR]
  • gi|85397858|gb|AAI04983.1| Interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [Homo sapiens] [NCBI NR]
  • gi|5923853|gb|AAD56385.1|AF180562_1 interleukin 12, P35 [Homo sapiens] [NCBI NR]
  • gi|4323579|gb|AAD16432.1| interleukin 12; natural killer cell stimulatory factor; cytotoxic lymphocyte maturation factor 35kDa subunit; p35 [Homo sapiens] [NCBI NR]
  • gi|24430219|ref|NP_000873.2| interleukin 12A precursor [Homo sapiens] [NCBI NR]
  • gi|189234|gb|AAA59937.1| natural killer cell stimulatory factor [Homo sapiens] [NCBI NR]
  • gi|119599062|gb|EAW78656.1| interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), isoform CRA_a [Homo sapiens] [NCBI NR]
  • pir||B38957 interleukin 12A precursor [validated] - human [NCBI NR]
    • Organism: Homo sapiens
    Length: 253 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWPPGSASQP PPSPAAATGL HPAARPVSLQ CRLSMCPARS LLLVATLVLL DHLSLARNLP  60
   61 VATPDPGMFP CLHHSQNLLR AVSNMLQKAR QTLEFYPCTS EEIDHEDITK DKTSTVEACL 120
  121 PLELTKNESC LNSRETSFIT NGSCLASRKT SFMMALCLSS IYEDLKMYQV EFKTMNAKLL 180
  181 MDPKRQIFLD QNMLAVIDEL MQALNFNSET VPQKSSLEEP DFYKTKIKLC ILLHAFRIRA 240
  241 VTIDRVMSYL NAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] PSI-BLAST 101.0 Heterodimeric interleukin-12 alpha chain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • interleukin-12 binding
    		•  6.97623072079116 bayes_pls_golite062009
  • cytokine receptor binding
    		•  6.47223189691244 bayes_pls_golite062009
  • interleukin-27 binding
    		•  6.42738636095917 bayes_pls_golite062009
  • interleukin-12 beta subunit binding
    		•  5.72528664872472 bayes_pls_golite062009
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • cytokine activity
    		•  5.22856893358132 bayes_pls_golite062009
  • growth factor activity
    		•  4.92105782010612 bayes_pls_golite062009
  • interleukin-12 receptor binding
    		•  4.74969286958651 bayes_pls_golite062009
  • protein binding
    		•  3.26483713001551 bayes_pls_golite062009
  • binding
    		•  2.48265117231403 bayes_pls_golite062009
  • prolactin receptor binding
    		•  2.45721634350294 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  2.37535614986843 bayes_pls_golite062009
  • hormone activity
    		•  2.25587306265428 bayes_pls_golite062009
  • growth hormone activity
    		•  1.87531277315347 bayes_pls_golite062009
  • ciliary neurotrophic factor receptor binding
    		•  1.79326213321183 bayes_pls_golite062009
  • interleukin-2 receptor binding
    		•  1.24568403220915 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  1.21666375770079 bayes_pls_golite062009
  • macrophage colony stimulating factor receptor binding
    		•  1.01092937856314 bayes_pls_golite062009
  • interferon-alpha/beta receptor binding
    		•  0.93290045827216 bayes_pls_golite062009
  • erythropoietin receptor binding
    		•  0.77580300541347 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.486790888007408 bayes_pls_golite062009
  • catalytic activity
    		•  0.246169290135575 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle