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View Structure Prediction Details

Protein: UTP23_MOUSE
Organism: Mus musculus
Length: 249 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP23_MOUSE.

Description E-value Query
Range
Subject
Range
gi|26335161 - gi|26335161|dbj|BAC31281.1| unnamed protein product [Mus musculus]
298.0 [0..1] [249..1]
UTP23 - UTP23, small subunit (SSU) processome component, homolog (yeast)
289.0 [0..1] [249..1]
gi|187282097, gi... - gi|187282097|ref|NP_001119738.1| UTP23, small subunit (SSU) processome component, homolog [Rattus no...
282.0 [0..1] [249..1]
gi|73974539 - gi|73974539|ref|XP_539141.2| PREDICTED: similar to CG17652-PA [Canis familiaris]
279.0 [0..1] [248..1]
UTP23_BOVIN - rRNA-processing protein UTP23 homolog OS=Bos taurus GN=UTP23 PE=2 SV=1
277.0 [0..1] [249..1]
gi|44981453, gi|... - gi|45185698|ref|NP_983414.1| ACR011Cp [Ashbya gossypii ATCC 10895], gi|44981453|gb|AAS51238.1| ACR01...
gi|44981453 - gi|44981453|gb|AAS51238.1| ACR011Cp [Ashbya gossypii ATCC 10895]
246.0 [0..1] [248..1]
gi|50731881 - gi|50731881|ref|XP_418400.1| PREDICTED: hypothetical protein [Gallus gallus]
241.0 [0..1] [222..1]
UTP23_SCHPO - rRNA-processing protein utp23 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=utp23 PE=3 S...
SPCC18.12c - rRNA processing protein
234.0 [0..1] [222..1]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKITRQKHAK KHLGFFRNNF GVREPYQILL DGTFCQAALR GRIQLRDQLP RYLMGETQLC  60
   61 TTRCVLKELE TLGKELYGAK LIAQKCQVRN CPHFKSPVSG SECLLSMVDE GNPHHYFVAT 120
  121 QDQNLSVKVK RTPGIPLMFI IQNTIVLDKP SPRTVAFVKA VE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1o4wA
Description: Hypothetical protein AF0591
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nuclease activity 2.9643999717473 bayes_pls_golite062009
exonuclease activity 2.73966722455965 bayes_pls_golite062009
DNA binding 2.08813762501061 bayes_pls_golite062009
nucleic acid binding 1.94354032094901 bayes_pls_golite062009
flap endonuclease activity 1.93047867791632 bayes_pls_golite062009
binding 1.92045449238153 bayes_pls_golite062009
endonuclease activity 1.76157945742159 bayes_pls_golite062009
endodeoxyribonuclease activity 1.70282544747112 bayes_pls_golite062009
5'-3' exonuclease activity 1.66809858159343 bayes_pls_golite062009
deoxyribonuclease activity 1.62584843390946 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.54085341767512 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.5104333947608 bayes_pls_golite062009
hydrolase activity 1.46573209130672 bayes_pls_golite062009
catalytic activity 1.37534898662234 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.0761952249864 bayes_pls_golite062009
protein binding 0.696235153462548 bayes_pls_golite062009
3'-5' exonuclease activity 0.50487165366129 bayes_pls_golite062009
exodeoxyribonuclease activity 0.421194877842092 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.404818231616342 bayes_pls_golite062009
5'-3' exodeoxyribonuclease activity 0.34527101309477 bayes_pls_golite062009
double-stranded DNA specific exodeoxyribonuclease activity 0.123105804280941 bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity 0.120278857913627 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [163-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGQLVSVHEK QSIKQLKEEQ GLVRNPDLRR RRRKKKKVGG PNPLSCLKKK KKAQDTKSPA  60
   61 SEKKRKRKRI RNRSTLKVSS EQQGAEG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle