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View Structure Prediction Details

Protein: C209D_MOUSE
Organism: Mus musculus
Length: 237 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C209D_MOUSE.

Description E-value Query
Range
Subject
Range
C209A_MOUSE - CD209 antigen-like protein A OS=Mus musculus GN=Cd209a PE=2 SV=1
183.0 [0..1] [237..1]
gi|157819491, gi... - gi|157819491|ref|NP_001102319.1| CD209d antigen [Rattus norvegicus], gi|149015587|gb|EDL74968.1| sim...
179.0 [0..1] [237..1]
gi|15383618 - gi|15383618|gb|AAK91865.1| sDC-SIGN2 type III isoform [Homo sapiens]
175.0 [0..1] [232..1]
209L2_MACMU - CD209 antigen-like protein 2 OS=Macaca mulatta GN=CD209L2 PE=1 SV=1
174.0 [0..1] [235..1]
gi|27356854 - gi|27356854|gb|AAL89535.1| putative CD209L1 protein [Pan troglodytes]
173.0 [0..5] [232..201]
gi|27356919 - gi|27356919|gb|AAL89543.1| putative CD209 protein [Gorilla gorilla]
CD209_GORGO - CD209 antigen OS=Gorilla gorilla gorilla GN=CD209 PE=3 SV=1
173.0 [0..4] [235..187]

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Predicted Domain #1
Region A:
Residues: [1-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSMESKTQ QVVIPEDEEC LMSGTRYSDI SSRLQTKFGI KSLAEYTKQS RNPLVLQLLS  60
   61 FLFLAGLLLI ILILVSKVPS SEVQNKIYQE LMQLKAEVHD GLCQPCARDW TFFNGSCYFF 120
  121 SKSQRNWHNS TTACQELGAQ LVIIETDEEQ TFLQQTSKAR GPTWMGLSDM HNEATWHWVD 180
  181 GSPLSPSFTR YWNRGEPNNV GDEDCAEFSG DGWNDLSCDK LLFWICKKVS TSSCTTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
monosaccharide binding 3.11313573656236 bayes_pls_golite062009
carbohydrate binding 2.63424321036563 bayes_pls_golite062009
receptor activity 2.50780218421666 bayes_pls_golite062009
transmembrane receptor activity 2.25703667932839 bayes_pls_golite062009
hyaluronic acid binding 2.24101091318298 bayes_pls_golite062009
molecular transducer activity 2.04530361540349 bayes_pls_golite062009
signal transducer activity 2.04530361540349 bayes_pls_golite062009
mannose binding 2.02769829616516 bayes_pls_golite062009
polysaccharide binding 2.00647699969727 bayes_pls_golite062009
pattern binding 1.93929977823971 bayes_pls_golite062009
fucose binding 1.84048523146965 bayes_pls_golite062009
binding 1.83602918816086 bayes_pls_golite062009
glycosaminoglycan binding 1.74017863387581 bayes_pls_golite062009
antigen binding 1.69692361913389 bayes_pls_golite062009
peptide antigen binding 1.21587238898951 bayes_pls_golite062009
sugar binding 1.08373701017943 bayes_pls_golite062009
calcium-dependent protein binding 1.03810546168048 bayes_pls_golite062009
zymosan receptor activity 0.943014275506551 bayes_pls_golite062009
MHC class Ib receptor activity 0.943014275506551 bayes_pls_golite062009
polysaccharide receptor activity 0.943014275506551 bayes_pls_golite062009
cell surface binding 0.847091868125047 bayes_pls_golite062009
protein binding 0.778335313480154 bayes_pls_golite062009
natural killer cell receptor activity 0.726020405011931 bayes_pls_golite062009
receptor binding 0.63610471733499 bayes_pls_golite062009
calcium ion binding 0.409714138901478 bayes_pls_golite062009
sialic acid binding 0.320555870924401 bayes_pls_golite062009
eukaryotic cell surface binding 0.21157949111795 bayes_pls_golite062009
natural killer cell lectin-like receptor binding 0.204348795793981 bayes_pls_golite062009
catalytic activity 0.10160549859022 bayes_pls_golite062009
0.0947750414934809 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle