YRC Public Data Repository - Protein Structure Prediction

Protein:	PSB3_MOUSE
Organism:	Mus musculus
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSB3_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|50760756 - gi\|50760756\|ref\|XP_418119.1\| PREDICTED: similar to Zgc:56374 [Gallus gallus]	199.0	[0..1]	[205..135]
gi\|56541012 - gi\|56541012\|gb\|AAH87457.1\| Unknown (protein for MGC:99279) [Xenopus laevis]	199.0	[0..1]	[205..1]
gi\|62858119, gi\|... - gi\|62858119\|ref\|NP_001016503.1\| proteasome (prosome, macropain) subunit, beta type 3 [Xenopus (Silur...	198.0	[0..1]	[205..1]
gi\|57091113 - gi\|57091113\|ref\|XP_537658.1\| PREDICTED: similar to Proteasome subunit beta type 3 (Proteasome theta ...	194.0	[0..1]	[205..1]
gi\|193788711, gi... - gi\|29124577\|gb\|AAH49010.1\| Psmb3 protein [Danio rerio], gi\|193788711\|ref\|NP_001123295.1\| proteasome ...	193.0	[0..1]	[205..1]
PSB3_RAT - Proteasome subunit beta type-3 OS=Rattus norvegicus GN=Psmb3 PE=1 SV=1 gi\|458731 - gi\|458731\|dbj\|BAA04824.1\| proteasome subunit RC10-II [Rattus sp.]	193.0	[0..1]	[205..1]
gi\|21465665, gi\|... - gi\|21465665\|pdb\|1IRU\|X Chain X, Crystal Structure Of The Mammalian 20s Proteasome At 2.75 A Resoluti... gi\|565647, gi\|10... - pir\|\|S55041 C 3.4.25.1 proteasome endopeptidase complex () beta chain C10-II - human, gi\|565647\|dbj...	193.0	[0..1]	[205..1]
PSB3_ONCMY - Proteasome subunit beta type-3 OS=Oncorhynchus mykiss GN=psmb3 PE=2 SV=1	193.0	[0..1]	[205..1]
gi\|109114735 - gi\|109114735\|ref\|XP_001084269.1\| PREDICTED: proteasome (prosome, macropain) subunit, beta type, 3 is... CCDS11328.1_1 - null	193.0	[0..1]	[205..1]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIMSYNGGA VMAMKGKNCV AIAADRRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV  60
   61 QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF 120
  121 ICSLDLIGCP MVTDDFVVSG TCSEQMYGMC ESLWEPNMDP EHLFETISQA MLNAVDRDAV 180
  181 SGMGVIVHVI EKDKITTRTL KARMD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1iruJ
Description:	Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	1.18139971903068	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: