YRC Public Data Repository - Protein Structure Prediction

Protein:	YF54_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	783 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YF54_SCHPO.

Description	E-value	Query Range	Subject Range
THI1_SCHPO - Thiamine repressible genes regulatory protein thi1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2... thi1 - transcription factor Thi1	316.0	[0..14]	[783..13]
gi\|499202 - gi\|499202\|gb\|AAA19010.1\| transcription factor [Schizosaccharomyces pombe]	295.0	[0..14]	[752..13]
gi\|85081614 - gi\|85081614\|ref\|XP_956755.1\| hypothetical protein NCU01478 [Neurospora crassa OR74A] gi\|28917831, gi\|... - gi\|32414875\|ref\|XP_327917.1\| hypothetical protein [Neurospora crassa], gi\|28917831\|gb\|EAA27519.1\| hy...	279.0	[0..28]	[782..57]
ASG1_YEAST - Activator of stress genes 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASG1 PE=1 SV... ASG1 - Zinc cluster protein proposed to function as a transcriptional regulator involved in the stress resp...	278.0	[0..21]	[768..2]
gi\|38566844 - gi\|38566844\|emb\|CAE76150.1\| related to transcriptional activator Mut3p [Neurospora crassa]	270.0	[0..28]	[782..57]
gi\|119194841, gi... - gi\|90306810\|gb\|EAS36441.1\| hypothetical protein CIMG_01795 [Coccidioides immitis RS], gi\|119194841\|r...	269.0	[0..2]	[775..31]
gi\|169775145 - gi\|169775145\|ref\|XP_001822040.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83769903 - gi\|83769903\|dbj\|BAE60038.1\| unnamed protein product [Aspergillus oryzae]	267.0	[0..2]	[780..33]
gi\|67536776, gi\|... - gi\|67536776\|ref\|XP_662162.1\| hypothetical protein AN4558.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	263.0	[0..2]	[780..33]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHEFSPENT AVLFEAMKQE QHNRRRRVPM ERRRRVVLAC FNCKARKVRC DGANPCKACA  60
   61 SNNLECTYPV KDEKEMDYSK DYFIDLSKRY KCLEYIVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.0
Match:	1zmeC
Description:	PUT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.56444258780502	bayes_pls_golite062009
DNA binding	4.26146437716972	bayes_pls_golite062009
nucleic acid binding	4.17369933547911	bayes_pls_golite062009
transcription factor activity	3.049435548132	bayes_pls_golite062009
sequence-specific DNA binding	2.98081393153291	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.93914501897006	bayes_pls_golite062009
binding	2.91929847152301	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	2.44382866473054	bayes_pls_golite062009
transcription activator activity	2.24483536326713	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [99-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLCSTKVSTY TTPSLIEVCN RISNQKSLLS SDVFSLNSES TNSQRDVDTL TQGALVCSQI  60
   61 QQDPTVVAED TNNGINADAS DQSVDEIMKL IGKIKVDSNG ESRYIGASAG EAFVDSVQSE 120
  121 LLVDPSFSEL SAYSHTHHSY PPNEH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.42
Match:	1pyiA
Description:	PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.34861813464065	bayes_pls_golite062009
DNA binding	4.03985756894684	bayes_pls_golite062009
nucleic acid binding	3.97978190843512	bayes_pls_golite062009
transcription factor activity	2.87348461329489	bayes_pls_golite062009
binding	2.82809978070212	bayes_pls_golite062009
sequence-specific DNA binding	2.77469997789536	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.70904317608141	bayes_pls_golite062009
transcription activator activity	2.1512787242583	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	2.08956709478484	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [244-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVNAVQKALS LLPPPEVSDF LIKSFYGHVQ ANFFFFHETL LRYRLNLIMS FQNPSVDPGF  60
   61 LCLLMMIFAL GSMFAHMEIR SASNPFDNPG KQFFDTARLL LPQVIQQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [351-441]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKPSLVQASI LMGLYLQSTL SQKSSYTYFG LSLSAAVANG LHRSCENPNI DPKTKELRNR  60
   61 LWWSVYTMDR LISIATGRPL SIADSECDAA L

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	34.080922
Match:	PF04082.9
Description:	No description for PF04082.9 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.699	0.197	transcription factor activity	a.118.8	TPR-like
View	Download	0.672	0.038	cytoplasm	a.24.3	Cytochromes
View	Download	0.833	0.034	cytoplasm	a.7.8	GAT domain
View	Download	0.746	0.008	zinc ion binding	a.26.1	4-helical cytokines
View	Download	0.744	N/A	N/A	a.26.1	4-helical cytokines

Predicted Domain #5

Region A:
Residues: [442-651]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTVVPELEIE GSASNVHNII SMSKIAKIMG KTMEQLYGTV NYKKNPINII ESLRADLEEW  60
   61 KRSLPPFQIL ENLDAEDPLF RANVHLHMTY DQAIIIMSRP VLLHKMKNAK NSPRVDRINE 120
  121 DCILAARHLI SLVHLLQNHS QLSCYSFFDY NYTFSSALVV LLHCVTEPCE EDDIAMQYAY 180
  181 SALDYMAEGN EAAKNCARVI RLFDAHLKGA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [652-783]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSDGNGNTSQ SGFMAWQRWI AEVSAKDEPE KLMSPYNKSI GGGRNSNSLT PNANLGADVS  60
   61 FFPTDDTSFL LDHSKLDDDL EKFASTLDPI KTTPDLANDS SLLNWANTDQ GMDIEGSWLG 120
  121 NMHPTWLDYV CP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.273	0.048	DNA binding	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: