YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: BZZ1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 642 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BZZ1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
229.0 [0..1] [496..2143]
gi|39972033, gi|... - gi|39972033|ref|XP_367407.1| hypothetical protein MGG_07332 [Magnaporthe grisea 70-15], gb|EAA56977....
208.0 [0..8] [641..10]
orf19.1699 - orf19.1699 CGDID:CAL0000193 Assembly 19, Contig19-10123 (206016, 207878) CDS, translated using codon...
gi|68468423, gi|... - gi|68468423|ref|XP_721771.1| potential actin filament organization protein Bzz1p [Candida albicans S...
198.0 [0..1] [642..1]
gi|49068338, gi|... - gi|71004648|ref|XP_756990.1| hypothetical protein UM00843.1 [Ustilago maydis 521], ref|XP_398458.1| ...
195.0 [0..1] [642..25]
BZZ1 - SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polym...
BZZ1_YEAST - Protein BZZ1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BZZ1 PE=1 SV=1
194.0 [0..7] [640..6]
gi|46137691, gi|... - gi|46137691|ref|XP_390537.1| hypothetical protein FG10361.1 [Gibberella zeae PH-1], gi|42544303|gb|E...
193.0 [0..8] [642..10]
gi|119191604, gi... - gi|90305194|gb|EAS34825.1| hypothetical protein CIMG_00179 [Coccidioides immitis RS], gi|119191604|r...
192.0 [0..8] [640..10]
gi|114189625, gi... - gi|115433272|ref|XP_001216773.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
189.0 [0..25] [640..18]

Back

Predicted Domain #1
Region A:
Residues: [1-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLETYKFSD ELHDDFKVVD SWINNGAKWL EDIQLYYKER SSIEKEYAQK LASLSNKYGE  60
   61 KKSRKSSALS VGDTPAMSAG SLECASLTTW SKILDELTRS SKTHQKLSDD YSLDIAEKLK 120
  121 KLESHIEALR KVYDDLYKKF SSEKETLLNS VKRAKVSYHE ACDDLESARQ KNDKYREQKT 180
  181 QRNLKLSESD MLDKKNKYLL RMLVYNAHKQ KFYNETLPTL LNHMQVLNEY RVSNLNEIWC 240
  241 NSFSIEKSLH DTLSQRTVEI QSEIAKNEPV LDSAMFGRHN SKNWALPADL HFEPSPIWHD 300
  301 TDALVV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 2eflA
Description: No description for 2eflA was found.

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 2.86582611923959 bayes_pls_golite062009
binding 2.2879693624429 bayes_pls_golite062009
protein binding 2.08046860800611 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.533946913012306 bayes_pls_golite062009
pyrophosphatase activity 0.492863553428448 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.48203970262288 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.481384553079895 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [307-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSCKNYLRN LLVHSKNDLG KQKGELVSLD SQLEGLRVDD PNSANQSFES KKASINLEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [366-513]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KELMVKARIE DLEVRINKIT SVANNLEEGG RFHDFKHVSF KLPTSCSYCR EIIWGLSKRG  60
   61 CVCKNCGFKC HARCELLVPA NCKNGEPEVA DDDAVDTSVT ATDDFDASAS SSNAYESYRN 120
  121 TYTDDMDSSS IYQTSLSNVK TEETTPAE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.85
Match: 1tbnA
Description: NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.13567713176414 bayes_pls_golite062009
protein binding 1.417409982197 bayes_pls_golite062009
GTPase regulator activity 0.852428113024117 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.590904037542168 bayes_pls_golite062009
myosin heavy chain kinase activity 0.433378144372842 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.36934922714234 bayes_pls_golite062009
diacylglycerol binding 0.161261456004319 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.117036271102062 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [514-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASKVDGVVL YDFTGEHEGV ITASEGQEFT LLEPDDGSGW VRVKIDGTDG LIPASYVKLN  60
   61 DELNTSVTLD GDSSYVKALY AYTAQSDMEL SIQEGDIIQV TNRNAGNGWS EGILNGVTGQ 120
  121 FPANYVTDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 4.94949685871786 bayes_pls_golite062009
cytoskeletal protein binding 4.41722924924158 bayes_pls_golite062009
actin filament binding 3.69427077755816 bayes_pls_golite062009
binding 2.55003340159545 bayes_pls_golite062009
protein binding 2.35325421236395 bayes_pls_golite062009
structural constituent of muscle 1.44117328570973 bayes_pls_golite062009
structural constituent of cytoskeleton 0.371928447183203 bayes_pls_golite062009
protein binding, bridging 0.230308623372106 bayes_pls_golite062009
molecular adaptor activity 0.211510977251932 bayes_pls_golite062009
transporter activity 0.0502941720831361 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle