YRC Public Data Repository - Protein Structure Prediction

Protein:	PSA5_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSA5_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|1498589 - gi\|1498589\|gb\|AAB93421.1\| 20S proteasome alpha subunit PSMA5 [Drosophila melanogaster]	271.0	[0..1]	[243..1]
gi\|218186097 - gi\|218186097\|gb\|EEC68524.1\| hypothetical protein OsI_36813 [Oryza sativa Indica Group] PSA5_ORYSJ - Proteasome subunit alpha type-5 OS=Oryza sativa subsp. japonica GN=PAE1 PE=2 SV=1 PSA5_ORYSA - Proteasome subunit alpha type 5 (EC 3.4.25.1) (20S proteasome alpha subunit E) (20S proteasome subun...	270.0	[0..1]	[242..1]
gi\|87248207, gi\|... - gi\|87248207\|gb\|ABD36156.1\| proteasome zeta subunit [Bombyx mori], gi\|114050993\|ref\|NP_001040146.1\| p...	269.0	[0..1]	[242..1]
PSA5A_ARATH - Proteasome subunit alpha type-5-A OS=Arabidopsis thaliana GN=PAE1 PE=1 SV=1	266.0	[0..1]	[242..1]
PSA5_SOYBN - Proteasome subunit alpha type-5 OS=Glycine max GN=PAE1 PE=2 SV=1	265.0	[0..1]	[242..1]
gi\|39971629, gi\|... - gi\|39971629\|ref\|XP_367205.1\| hypothetical protein MG07130.4 [Magnaporthe grisea 70-15], gb\|EAA56775....	265.0	[0..1]	[242..1]
gi\|32408341, gi\|... - gi\|32408341\|ref\|XP_324652.1\| hypothetical protein [Neurospora crassa], gi\|28923660\|gb\|EAA32830.1\| pr... gi\|85105938 - gi\|85105938\|ref\|XP_962066.1\| proteasome component PUP2 [Neurospora crassa OR74A]	264.0	[0..1]	[242..1]
gi\|16943777 - gi\|16943777\|emb\|CAD10778.1\| 20S proteasome subunit alpha V [Physcomitrella patens]	263.0	[0..1]	[242..1]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFMTRSEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGV KTKDAVVLGV EKRLTSPLME  60
   61 SHSVEKLFEI DSHIGCAISG LTADARTIIE HARVQTQNHR FTYDEPQGIE STTQSICDLA 120
  121 LRFGEGEDGE ERIMSRPFGV ALLIAGIDEH GPQLYHSEPS GTYFRYEAKA IGSGSEPAKS 180
  181 ELVKEFHKDM TLEEAEVLIL KVLRQVMEEK LDSKNVQLAK VTAEGGFHIY NDEEMADAVA 240
  241 REQQRMD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.522879
Match:	1iruE
Description:	Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
binding	1.75265921676176	bayes_pls_golite062009
nucleic acid binding	1.39216781236247	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: