YRC Public Data Repository - Protein Structure Prediction

Protein:	PMT1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	893 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PMT1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|85118928 - gi\|85118928\|ref\|XP_965543.1\| hypothetical protein NCU01912 [Neurospora crassa OR74A] gi\|32417248, gi\|... - gi\|32417248\|ref\|XP_329102.1\| hypothetical protein [Neurospora crassa], gi\|28927353\|gb\|EAA36307.1\| hy...	906.0	[0..9]	[886..49]
gi\|42548795, gi\|... - gi\|46130662\|ref\|XP_389111.1\| hypothetical protein FG08935.1 [Gibberella zeae PH-1], gi\|42548795\|gb\|E...	874.0	[0..11]	[838..52]
gi\|38100606, gi\|... - gi\|86196682\|gb\|EAQ71320.1\| hypothetical protein MGCH7_ch7g727 [Magnaporthe grisea 70-15], gi\|3997097...	857.0	[0..9]	[892..42]
gi\|88182545, gi\|... - gi\|88182545\|gb\|EAQ90013.1\| hypothetical protein CHGG_06632 [Chaetomium globosum CBS 148.51], gi\|1161...	844.0	[0..4]	[874..21]
gi\|49094874, gi\|... - gi\|67537182\|ref\|XP_662365.1\| hypothetical protein AN4761.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	843.0	[0..3]	[872..29]
gi\|159127974 - gi\|159127974\|gb\|EDP53089.1\| protein mannosyltransferase 1 [Aspergillus fumigatus A1163] gi\|66852598, gi\|... - gi\|71000555\|ref\|XP_754961.1\| protein mannosyltransferase 1 [Aspergillus fumigatus Af293], gi\|6685259...	831.0	[0..50]	[859..74]
gi\|111070562 - gi\|111070562\|gb\|EAT91682.1\| hypothetical protein SNOG_00187 [Phaeosphaeria nodorum SN15]	823.0	[0..50]	[878..90]
gi\|83773212 - gi\|83773212\|dbj\|BAE63339.1\| unnamed protein product [Aspergillus oryzae] gi\|169780016 - gi\|169780016\|ref\|XP_001824472.1\| hypothetical protein [Aspergillus oryzae RIB40]	817.0	[0..32]	[832..56]
PMT1 - Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to prote... PMT1_YEAST - Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 2...	812.0	[0..8]	[787..23]
gi\|115402577, gi... - gi\|115402577\|ref\|XP_001217365.1\| hypothetical protein ATEG_08779 [Aspergillus terreus NIH2624], gi\|1...	808.0	[0..46]	[864..70]

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Predicted Domain #1

Region A:
Residues: [1-144]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKQSTFQDP KEKHRIQRDV KLSRPRKRFS FLDYVVVIFL TVVAFCVRAQ RLMNPAKVVF  60
   61 EELRYYNYAV DYVNNKLLMD VYPPLGKLLF SLVAALTGNK YELNTLDEPG QQYPFTDVAY 120
  121 SMRLFTCLLG SLLVPLMYGT VYFP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [145-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKSKTAASLA ALFVIFDNGL ITMSRYIMIE IPALYFMSLT AFYWSVYEAQ QKRPFSLRWH  60
   61 TSLLSTGVAL GLALSTKLSA MFTFGWLLIL AAFHLWNLLG DLSVPMYRIV KHLFSYIFYL 120
  121 IGVPITVYLA VFAVHSHIAY KASVADAFLP PEHRHALAGN RFDDQFADVA YG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1e6dM
Description:	M (medium) subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [317-512]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLVTIRNAIP EHGYLHSSEL LYPEGTEQQI ISLVDEPNQN ALWIIEHEHS QDNNRSNIEL  60
   61 LKDGSVVRLR HVMTGRALHS HEHKPIVSNN DWQLEASAYG GFGFEGDAND LFRIQILEKK 120
  121 SKHATSNGTV ETLNTKFRLI HVFANCELMS SHRRFPDWGD YQREVTCCRN CVERSTTWFI 180
  181 ESNYHDGLPS DSRKIT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.522879
Match:	1t9fA
Description:	Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dolichyl-phosphate-mannose-protein mannosyltransferase activity	7.33543412640964	bayes_pls_golite062009
mannosyltransferase activity	6.32966341675541	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.60661923349025	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.57555885876017	bayes_pls_golite062009
receptor activity	1.98562812678228	bayes_pls_golite062009
binding	1.71578680186328	bayes_pls_golite062009
cation channel activity	1.66500687404195	bayes_pls_golite062009
ion channel activity	1.61859406934521	bayes_pls_golite062009
substrate-specific channel activity	1.57127083095499	bayes_pls_golite062009
passive transmembrane transporter activity	1.55374970486978	bayes_pls_golite062009
channel activity	1.55374970486978	bayes_pls_golite062009
inositol-1,4,5-trisphosphate receptor activity	1.54960024640698	bayes_pls_golite062009
molecular transducer activity	1.01765765844557	bayes_pls_golite062009
signal transducer activity	1.01765765844557	bayes_pls_golite062009
transferase activity	0.981084601370981	bayes_pls_golite062009
calcium channel activity	0.85901349040585	bayes_pls_golite062009
catalytic activity	0.659936859803906	bayes_pls_golite062009
calcium-release channel activity	0.65133561512386	bayes_pls_golite062009
gated channel activity	0.53737429019655	bayes_pls_golite062009
ligand-gated ion channel activity	0.52162184692236	bayes_pls_golite062009
ligand-gated channel activity	0.52162184692236	bayes_pls_golite062009
protein binding	0.428075756729427	bayes_pls_golite062009
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	0.152598505509111	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [513-714]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRKPGFLESF VEHNKLMWLK DRKMGDGHVY ESSALTWPLL LGPLRFFYEQ HLQVFFMGNP  60
   61 FVWYSVISLV AFFVIVQIFC LARWNLGYND FGPSAFHYNY NIGKFVVAWL LHWAPYILET 120
  121 DRVFLYHYLP ALYFGIAALG VSWSFLGNAV FGNRTAYKAL SVIIMALMFL VYRLYSPFTY 180
  181 MTTLTKSSCR ALELKGSWNF HC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [715-802]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTYLDNLSDY KFSSDAGETY FEKAAPHPFV YSEDTAKKSE GDTPLNKNLN DYYPSWDQRV  60
   61 EAGYKLAAQQ KAEQEAREAA EKAASEAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.39794
Match:	1w9rA
Description:	Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [803-893]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERSSSEAAAS SSSESVAAAS VEAERLAMEA DEFNGASETV DGASVEAERS AMEAAALNNA  60
   61 AESTEVVGSS PESVASEQEE NVAESAQARV E

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: