YRC Public Data Repository - Protein Structure Prediction

Protein:	TFH47_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	421 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFH47_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|3327882 - gi\|3327882\|dbj\|BAA31745.1\| SSL1 [Schizosaccharomyces pombe]	415.0	[0..30]	[421..1]
SSL1_YEAST - Suppressor of stem-loop protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSL1 P... gi\|190406046 - gi\|190406046\|gb\|EDV09313.1\| suppressor of stem-loop protein 1 [Saccharomyces cerevisiae RM11-1a] SSL1 - Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kina...	399.0	[0..12]	[418..48]
gi\|49643519 - gi\|49643519\|emb\|CAG99471.1\| KLLA0E09615p [Kluyveromyces lactis] gi\|49643519, gi\|... - gi\|50308759\|ref\|XP_454384.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643519\|emb\|CAG9947...	390.0	[0..2]	[418..47]
gi\|45188211, gi\|... - gi\|45188211\|ref\|NP_984434.1\| ADR338Cp [Ashbya gossypii ATCC 10895], gi\|44983055\|gb\|AAS52258.1\| ADR33... gi\|44983055 - gi\|44983055\|gb\|AAS52258.1\| ADR338Cp [Ashbya gossypii ATCC 10895]	388.0	[0..34]	[418..80]
gi\|42552804, gi\|... - gi\|46123249\|ref\|XP_386178.1\| hypothetical protein FG06002.1 [Gibberella zeae PH-1], gi\|42552804\|gb\|E...	368.0	[0..10]	[418..19]
gi\|49525847 - gi\|49525847\|emb\|CAG59466.1\| unnamed protein product [Candida glabrata] gi\|50288221, gi\|... - gi\|50288221\|ref\|XP_446539.1\| unnamed protein product [Candida glabrata], gi\|49525847\|emb\|CAG59466.1\|...	366.0	[0..29]	[418..44]
gi\|169776637 - gi\|169776637\|ref\|XP_001822785.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83771520 - gi\|83771520\|dbj\|BAE61652.1\| unnamed protein product [Aspergillus oryzae]	366.0	[0..6]	[418..2]
gi\|39977611, gi\|... - gi\|39977611\|ref\|XP_370193.1\| hypothetical protein MGG_06690 [Magnaporthe grisea 70-15], gb\|EAA55033....	365.0	[0..25]	[418..39]
TF2H2_RAT - General transcription factor IIH subunit 2 OS=Rattus norvegicus GN=Gtf2h2 PE=1 SV=1	363.0	[0..29]	[416..2]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNENQKSFDS DKSESEDEQK NGRVKVRSRK TDDNEGYTWE GEYQRSWDIV QEDAEGSLVG  60
   61 VIAGLIQSGK RKRLLRDTTP LQRGIIRHMV LVLDLSNSME ERDFHHKRFD LQIKYASEFV 120
  121 LEFFEQNPIS QLSIIGVMDG IAHRITDLHG NPQSHIQKLK SLRDCSGNFS LQNALEMARA 180
  181 SLSHIASHGT REVLIIFGSI LSSDPGDIFK TIDALVHDSI RVRIVGLAAE VAICKEICNK 240
  241 TNSSTKNAYG VVISEQHFRE LLLESTIPPA TDSAKTTDAS LVMMGFPSKV VEQLPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	2ok5A
Description:	No description for 2ok5A was found.

Predicted functions:

Term	Confidence	Notes
binding	2.55976325410124	bayes_pls_golite062009
DNA binding	1.67175195853604	bayes_pls_golite062009
nucleic acid binding	1.66804415166051	bayes_pls_golite062009
protein binding	1.4332924081006	bayes_pls_golite062009
protein complex binding	0.68878168136573	bayes_pls_golite062009
hydrolase activity	0.564965244474085	bayes_pls_golite062009
structure-specific DNA binding	0.450760554291027	bayes_pls_golite062009
protein dimerization activity	0.4223194470523	bayes_pls_golite062009
protein heterodimerization activity	0.32921284315242	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [297-421]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LCACHSIPSR GGFHCPRCKA KVCTLPIECP SCSLVLILST HLARSYHHLF PLKNWSEIPW  60
   61 SANPKSTHCF ACQLPFPKPP VSPFDESTSS MRYACPSCKN HFCLDCDVFA HEQLHECYGC 120
  121 QCSGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.0
Match:	1z60A
Description:	Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: