| Protein: | XRN1_SCHPO |
| Organism: | Schizosaccharomyces pombe 972h- |
| Length: | 1328 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XRN1_SCHPO.
| Description | E-value | Query Range |
Subject Range |
|
|
1701.0 | [0..1] | [1257..1] |
|
|
1692.0 | [0..1] | [1265..1] |
|
|
1647.0 | [0..1] | [1256..1] |
|
|
1643.0 | [0..1] | [1258..1] |
|
|
1642.0 | [0..1] | [1264..1] |
|
|
1632.0 | [0..1] | [1258..1] |
|
|
1620.0 | [0..1] | [1258..1] |
|
|
1617.0 | [0..1] | [1299..1] |
|
|
1613.0 | [0..1] | [1299..1] |
|
Region A: Residues: [1-483] |
1 11 21 31 41 51
| | | | | |
1 MGIPKFFRWM SERYPLCSQL IENDRIPEFD NLYLDMNGIL HNCTHKNDDH SSPPLPEEEM 60
61 YIAIFNYIEH LFEKIKPKKL LYMAVDGCAP RAKMNQQRSR RFRTAKDAHD ARLKAERNGE 120
121 DFPEEQFDSN CITPGTTFME RVSRQLYYFI HKKVTNDSQW QNIEVIFSGH DCPGEGEHKI 180
181 MEYIRTQKAQ PSYNPNTRHC LYGLDADLIM LGLLSHDPHF CLLREEVTFG PASRNRSKEL 240
241 AHQKFYLLHL SLLREYLEFE FQECRSTFTF KYDLEKILDD FILLAFFVGN DFLPHLPGLH 300
301 INEGALALMF SIYKKVMPSA GGYINEKGVI NMARLELILL ELENFEKEIF KAEVSETKNN 360
361 GNSDKPSFDF LKYITESTND IKAMTGEQKN YFLQIKKFLS SREPFIDFSA NISSVDQRFL 420
421 RRLCNDLHLS FSKIIKVDGT HLLRITFRDL EFNDEDEDEI EQDEIERVLQ KYDNIPLLNE 480
481 EQA
|
| Detection Method: |  |
| Confidence: | 1.15 |
| Match: | 1ul1X |
| Description: | Crystal structure of the human FEN1-PCNA complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| endonuclease activity | 2.8669665385948 | bayes_pls_golite062009 |
| hydrolase activity | 2.47801245425307 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.24517620525137 | bayes_pls_golite062009 |
| nuclease activity | 2.0989149357263 | bayes_pls_golite062009 |
| exonuclease activity | 1.76587867909916 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 1.74349203224875 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 1.68760157046614 | bayes_pls_golite062009 |
| ribonuclease activity | 1.49206381939599 | bayes_pls_golite062009 |
| catalytic activity | 1.27951740231695 | bayes_pls_golite062009 |
| DNA binding | 1.02247981478192 | bayes_pls_golite062009 |
| nucleic acid binding | 0.991719217031501 | bayes_pls_golite062009 |
| binding | 0.829502253184465 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.79417076649627 | bayes_pls_golite062009 |
| flap endonuclease activity | 0.405877291452351 | bayes_pls_golite062009 |
| 5'-3' exonuclease activity | 0.371408632109349 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.267787854683683 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 0.260397221344929 | bayes_pls_golite062009 |
| protein binding | 0.256860561043644 | bayes_pls_golite062009 |
| ribonuclease H activity | 0.234391225960316 | bayes_pls_golite062009 |
| endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.158336939964254 | bayes_pls_golite062009 |
| endoribonuclease activity | 0.097472492148219 | bayes_pls_golite062009 |
|
Region A: Residues: [484-549] |
1 11 21 31 41 51
| | | | | |
1 LKEKNVEKDF IQWKDDYYRS KVGFSYYDEE ALKAMAERYV EGLQWVLFYY YRGCQSWGWY 60
61 YNYHFA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [550-780] |
1 11 21 31 41 51
| | | | | |
1 PKISDVLKGL DVKIDFKMGT PFRPFEQLMA VLPARSQALV PPCFRDLMVN SESPIIDFYP 60
61 ENFALDQNGK TASWEAVVII PFIDETRLID ALASKDKFLT EEERKRNSFN APTVFSLAED 120
121 YTSFYPSSLP SLFPDLVTRC IQKPYSLPSM EGKEYLVGLC PGVFLGAFGM VGFPSFHTLK 180
181 HKAELVYHGI NVFGNESRNP SVIVNVEDVK SALTSEQIAM QYVGKRIFVD W
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [781-870] |
1 11 21 31 41 51
| | | | | |
1 PYLREAYVES AMDESYMYLA SNSTIEKRDL AEIEKSQWGR KCSHKIREYS KRFGVLFGDI 60
61 SLLLQVRPIK GLEYTREGAL VKIFNESVLE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [871-1043] |
1 11 21 31 41 51
| | | | | |
1 DYPAQLVVEK IAIDDPRFTE REAPPVEVEY PPGTKAFHLG EYNYGRPAQI TGCKDNKLII 60
61 WLSTAPGLDA QWGRVLVNDS KSKEKYYPSY IVAKLLNIHP LLLSKITSSF LISNGTKREN 120
121 IGLNLKFDAR NQKVLGFSRK STKGWEFSNK TVALVKEYIN TFPQLFNILT THA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1044-1217] |
1 11 21 31 41 51
| | | | | |
1 TKDNLTVKDC FPKDDTQQLA AVKHWIKEKG INSLTRVSLD EDALDSDIIK LIEEKASTID 60
61 STYQVPKKVF GVPRYALLKP SQTRGILHSQ EFALGDRVVY VQDSGKVPIA AYGTVVGIML 120
121 HHLDVVFDLP FMSGTTLDGR CSPYHGMQVE VSMVLNVTNP QFVVNTRAGK NRKT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1218-1328] |
1 11 21 31 41 51
| | | | | |
1 NVSANNVSQG TDSRLVTKPT STFPSPPSPP SSSVWNKREH HPKPFSLHQV PPPESLIHKS 60
61 KSKFSKGNHH STNGTQSIRG RGGKRGKPLR SKELNRKHDH IVQPMGKLQI N
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
