YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|165937197, gi...
Organism:	Yersinia pestis biovar Orientalis str. IP275
Length:	505 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|165937197, gi....

Description	E-value	Query Range	Subject Range
gi\|238718693, gi... - gi\|77960842\|ref\|ZP_00824697.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Yers...	0.0	[1..505]	[1..505]
gi\|238785198, gi... - gi\|77957376\|ref\|ZP_00821434.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Yers...	0.0	[1..505]	[1..505]
gi\|238795096, gi... - gi\|77976973\|ref\|ZP_00832436.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Yers...	0.0	[1..505]	[1..505]
gi\|238723277, gi... - gi\|77975505\|ref\|ZP_00831040.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Yers...	0.0	[1..505]	[1..505]
gi\|49612501, gi\|... - gi\|50121975\|ref\|YP_051142.1\| amidophosphoribosyltransferase [Pectobacterium atrosepticum SCRI1043], ...	0.0	[1..505]	[1..505]
gi\|115513626, gi... - gi\|117624502\|ref\|YP_853415.1\| amidophosphoribosyltransferase [Escherichia coli APEC O1], gi\|11551362... gi\|187771012, gi... - gi\|187771012\|gb\|EDU34856.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4196], g... gi\|91073182, gi\|... - gi\|91211608\|ref\|YP_541594.1\| amidophosphoribosyltransferase [Escherichia coli UTI89], gi\|91073182\|gb... gi\|168767942, gi... - gi\|189362890\|gb\|EDU81309.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4486], g... gi\|15832450, gi\|... - gi\|15832450\|ref\|NP_311223.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. Sakai], g... gi\|189372889, gi... - gi\|189372889\|gb\|EDU91305.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC869], gi... gi\|110642516, gi... - gi\|110642516\|ref\|YP_670246.1\| amidophosphoribosyltransferase [Escherichia coli 536], gi\|110344108\|gb... gi\|168780171, gi... - gi\|189001887\|gb\|EDU70873.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4076], g... gi\|195935691 - gi\|195935691\|ref\|ZP_03081073.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4024... gi\|189378916, gi... - gi\|189378916\|gb\|EDU97332.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC508], gi... gi\|208813534, gi... - gi\|208813534\|ref\|ZP_03254863.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4045... gi\|208809191, gi... - gi\|208809191\|ref\|ZP_03251528.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4206... gi\|188017294, gi... - gi\|188017294\|gb\|EDU55416.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4113], g... gi\|189368340, gi... - gi\|189368340\|gb\|EDU86756.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501], g... gi\|168755068, gi... - gi\|189357748\|gb\|EDU76167.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4401], g... gi\|83570132, gi\|... - gi\|83570132\|ref\|ZP_00921579.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Shig... gi\|75243123, gi\|... - gi\|75243123\|ref\|ZP_00726829.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|227887370, gi... - gi\|227887370\|ref\|ZP_04005175.1\| amidophosphoribosyltransferase [Escherichia coli 83972], gi\|22783572... gi\|188495078, gi... - gi\|75515677\|ref\|ZP_00737812.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|254794205, gi... - gi\|254794205\|ref\|YP_003079042.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. TW143... gi\|209158630, gi... - gi\|209397230\|ref\|YP_002271721.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC411... gi\|208821678, gi... - gi\|208821678\|ref\|ZP_03261998.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4042... gi\|217327559, gi... - gi\|217327559\|ref\|ZP_03443642.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 str. TW1458... gi\|215265597, gi... - gi\|215487525\|ref\|YP_002329956.1\| amidophosphoribosyltransferase [Escherichia coli O127:H6 str. E2348... gi\|218690472, gi... - gi\|218690472\|ref\|YP_002398684.1\| amidophosphoribosyltransferase [Escherichia coli ED1a], gi\|21842803... gi\|218365994, gi... - gi\|218559225\|ref\|YP_002392138.1\| amidophosphoribosyltransferase [Escherichia coli S88], gi\|218365994... gi\|218432939, gi... - gi\|218705842\|ref\|YP_002413361.1\| amidophosphoribosyltransferase [Escherichia coli UMN026], gi\|218432... gi\|218370774, gi... - gi\|218700788\|ref\|YP_002408417.1\| amidophosphoribosyltransferase [Escherichia coli IAI39], gi\|2183707... gi\|26248700, gi\|... - gi\|26248700\|ref\|NP_754740.1\| amidophosphoribosyltransferase [Escherichia coli CFT073], gi\|26109105\|g... gi\|209764850, gi... - pir\|\|E85872 amidophosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|12516671, gi\|... - gi\|15802859\|ref\|NP_288886.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7 EDL933], gi\|12... gi\|15832450, gi\|... - gi\|15832450\|ref\|NP_311223.1\| amidophosphoribosyltransferase [Escherichia coli O157:H7], gi\|13362666\|...	0.0	[1..505]	[1..505]
gi\|213852683 - gi\|213852683\|ref\|ZP_03382215.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|16761287 - gi\|16761287\|ref\|NP_456904.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|213426983 - gi\|213426983\|ref\|ZP_03359733.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213161329 - gi\|213161329\|ref\|ZP_03347039.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213646795 - gi\|213646795\|ref\|ZP_03376848.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213582920 - gi\|213582920\|ref\|ZP_03364746.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|25286956, gi\|... - gi\|25286956\|pir\|\|AH0801 amidophosphoribosyltransferase (EC 2.4.2.14) [imported] - Salmonella enteric... gi\|29141017, gi\|... - gi\|29141017\|ref\|NP_804359.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser...	0.0	[1..505]	[1..505]
gi\|224583149, gi... - gi\|224583149\|ref\|YP_002636947.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|206709583, gi... - gi\|207857780\|ref\|YP_002244431.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205273256, gi... - gi\|205353475\|ref\|YP_002227276.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|204321519, gi... - gi\|204928975\|ref\|ZP_03220118.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|199605838, gi... - gi\|200388740\|ref\|ZP_03215352.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|198242494, gi... - gi\|198242494\|ref\|YP_002216435.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197361675, gi... - gi\|197361675\|ref\|YP_002141311.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197262622, gi... - gi\|197262622\|ref\|ZP_03162696.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|197212987, gi... - gi\|197249284\|ref\|YP_002147323.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|62128567, gi\|... - gi\|62180934\|ref\|YP_217351.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194734420, gi... - gi\|194734420\|ref\|YP_002115433.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|194471463, gi... - gi\|194471463\|ref\|ZP_03077447.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|194409186, gi... - gi\|194450882\|ref\|YP_002046418.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|56126998, gi\|... - gi\|56412741\|ref\|YP_149816.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194444570, gi... - gi\|194444570\|ref\|YP_002041626.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205344727, gi... - gi\|205344727\|gb\|EDZ31491.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168465927, gi... - gi\|195631420\|gb\|EDX49980.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205349326, gi... - gi\|205349326\|gb\|EDZ35957.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205338382, gi... - gi\|205338382\|gb\|EDZ25146.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|197289640, gi... - gi\|197289640\|gb\|EDY29003.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168229738, gi... - gi\|205335611\|gb\|EDZ22375.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|161612903, gi... - gi\|161612903\|ref\|YP_001586868.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|238912359 - gi\|238912359\|ref\|ZP_04656196.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ...	0.0	[1..505]	[1..505]
lcl\|NC_016856.1_... - [gene=purF] [protein=amidophosphoribosyltransferase] [protein_id=YP_005238444.1] [location=complemen... gi\|16420905, gi\|... - gi\|16765689\|ref\|NP_461304.1\| amidophosphoribosyltransferase [Salmonella typhimurium LT2], gi\|1642090... gi\|167993050, gi... - gi\|205328827\|gb\|EDZ15591.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero...	0.0	[1..505]	[1..505]
EG10794 - amidophosphoribosyltransferase / Amidophosphoribosyltransferase, purine synthesis; also known as glu... gi\|124526477, gi... - gi\|124526477\|ref\|ZP_01698430.1\| amidophosphoribosyltransferase [Escherichia coli B], gi\|124501948\|gb... gi\|253974222, gi... - gi\|254162321\|ref\|YP_003045429.1\| amidophosphoribosyltransferase [Escherichia coli B str. REL606], gi... gi\|24052752, gi\|... - gi\|24113684\|ref\|NP_708194.1\| amidophosphoribosyltransferase [Shigella flexneri 2a str. 301], gi\|2405... gi\|253323808, gi... - gi\|254289082\|ref\|YP_003054830.1\| amidophosphoribosyltransferase [Escherichia coli BL21(DE3)], gi\|253... gi\|30041993, gi\|... - gi\|30063738\|ref\|NP_837909.1\| amidophosphoribosyltransferase [Shigella flexneri 2a str. 2457T], gi\|30... gi\|242377945, gi... - gi\|251785672\|ref\|YP_002999976.1\| hypothetical protein B21_02197 [Escherichia coli BL21], gi\|24237794... gi\|238859974, gi... - gi\|238901487\|ref\|YP_002927283.1\| amidophosphoribosyltransferase [Escherichia coli BW2952], gi\|238859... gi\|89109132, gi\|... - gi\|89109132\|ref\|AP_002912.1\| amidophosphoribosyltransferase [Escherichia coli str. K-12 substr. W311... gi\|157156919, gi... - gi\|75187094\|ref\|ZP_00700361.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|195183051 - gi\|195183051\|dbj\|BAG66611.1\| amidophosphoribosyltransferase [Escherichia coli O111:H-] gi\|194429427, gi... - gi\|75209299\|ref\|ZP_00709539.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|83588295, gi\|... - gi\|83588295\|ref\|ZP_00926920.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|187427752, gi... - gi\|75177899\|ref\|ZP_00697961.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Shig... gi\|193062290, gi... - gi\|75259771\|ref\|ZP_00731073.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|74312829, gi\|... - gi\|74312829\|ref\|YP_311248.1\| amidophosphoribosyltransferase [Shigella sonnei Ss046], gi\|73856306\|gb\|... gi\|191169476, gi... - gi\|75227192\|ref\|ZP_00713996.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... gi\|193068153, gi... - gi\|75238095\|ref\|ZP_00722100.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Esch... PUR1_SHIFL - Amidophosphoribosyltransferase OS=Shigella flexneri GN=purF PE=3 SV=2 PUR1_ECOLI - Amidophosphoribosyltransferase (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase... gi\|170019379, gi... - gi\|170019379\|ref\|YP_001724333.1\| amidophosphoribosyltransferase [Escherichia coli ATCC 8739], gi\|169... EG10794 - amidophosphoribosyltransferase / Amidophosphoribosyltransferase, purine synthesis; also known as glu... gi\|169889763, gi... - gi\|170081928\|ref\|YP_001731248.1\| amidophosphoribosyltransferase [Escherichia coli str. K-12 substr. ... gi\|218554867, gi... - gi\|218554867\|ref\|YP_002387780.1\| amidophosphoribosyltransferase [Escherichia coli IAI1], gi\|21836163...	0.0	[1..505]	[1..505]

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Predicted Domain #1

Region A:
Residues: [1-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIVGIAGF TPVNQSIYDA LMVLQHRGQD AAGIVTIDAH NGFRLRKANG LVKDVFETRH  60
   61 MLRLQGNMGI GHVRYPTAGS SSASEAQPFY VNSPFGITLA HNGNLTNAHQ LRKKLFEVSR 120
  121 RHVNTTSDSE ILLNIFASEL DRFQHYPLES DNIFAAVAAT HQLIRGAYAC VAMIIGHGMV 180
  181 AFRDPNGIRP LVIGKRTLAD GRNEYMVASE SVALDTLDFE FLRDVAPGEA VYITEKGQLF 240
  241 TRQCAENPKY NPCLFEYVYF ARPDSFMDKI SVYSARVRMG QKLGTKIAKQ WEDMDIDVVI 300
  301 PIPETSCDIA LEIARILDKP YRQGFVKNRY VGRTFIMPGQ QERRKSVRRK LNANRAEFRG 360
  361 KNVLLVDDSI VRGTTSEQIV EMAREAGAKK VYFASAAPEI RFPNVYGIDM PSANELIAHG 420
  421 REVDEIRQLI GADALIFQDL TDLIDAVRED NPDITQFECS VFNGIYVTKD VDQSYLEYLE 480
  481 SLRNDDAQAL RSHNEAENLE MHNEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	119.0
Match:	1ecbA
Description:	Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.21367942706564	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	0.985266832225609	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	0.625087274084001	bayes_pls_golite062009
ligase activity	0.204093345072151	bayes_pls_golite062009
nucleic acid binding	0.202128134374461	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009
endopeptidase activity	0.0940838340168359	bayes_pls_golite062009
peptidase activity	0.0898497842822991	bayes_pls_golite062009
transcription regulator activity	0.057753538747651	bayes_pls_golite062009
binding	0.0515528196477861	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.012663147802059	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: