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View Structure Prediction Details

Protein: gi|113194754, gi...
Organism: Drosophila melanogaster
Length: 1148 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|113194754, gi....

Description E-value Query
Range
Subject
Range
gi|114691994 - gi|114691994|ref|XP_001140926.1| PREDICTED: similar to NLGN4 isoform 5 [Pan troglodytes verus]
gi|114691898 - gi|114691898|ref|XP_001144736.1| PREDICTED: similar to NLGN4 isoform 4 [Pan troglodytes]
763.0 [0..128] [1050..18]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMLLSKRQL PPSAATRTRR KVPPTRRRST WALSSLLALV VLDICIARCL AAGISYSSNS  60
   61 GNLSTSQKSP SSANNGGLVL IGSSSATSSS VPSLSLTSSS SAGLSSPGSS SSSSSSSTST 120
  121 SGSNSNRSSR PTSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [135-797]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSNSNSNYSP NHDQLPAQLS SRIINTRNGA ISGVIVQLDG RHLDPVEAYR GIPYASPPVG  60
   61 NLRFMPPVSA AMWSGVKKAD RFSPVCPQRL PDIHNETAAL ERMPKGRLEY LKRLLPYLQN 120
  121 QSEDCLYLNI YVPIQVGSRD SSGSSSSSSA GSSSSGSGGS SSSSSSSSTS SSSAGSGSPA 180
  181 KYPVLVFVHG ESYEWNSGNP YDGSVLASYG QILVVTINYR LGVLGFLNAN TDRYSKLPAN 240
  241 YGLMDIIAAL HWLKENIAAF GGDPNSITLA GHGTGAACVH FLISSMAVPE GLLFNRAILM 300
  301 SGSGLAPWSL VSNPAKYAAI VAHHVNCASD LPHAHLMKCL REKTLDQLLS VPIRPPEFGF 360
  361 AFGPSIDGVV IDGGDYVPPA PGSPAAQAQA QASTAAGNGL GGEAGIAAAG GWGTPGQLEN 420
  421 IGRYDLMAGV TRAEAFFSFN SGDVQYGIEA DRRSRILKAY VRNTYTFHLN EIFATIVNEY 480
  481 TDWERPVQHP INIRDETLEA LSDAQVVAPA AQTVDLHSAD HRNSYLYVFD YQTRFGDYPQ 540
  541 RQGCIHGEDL PYIFGAPLVG GFNHFTRNYT KTEISLSEVV MFYWSNFVRT GNPNEQMETE 600
  601 HGSRQERSRY KTIEWTAYES VHKKYLNFDT KPKLKNHYRA HRLSFWLNLI PDLHKPGGDN 660
  661 VPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.0
Match: 2pm8A
Description: No description for 2pm8A was found.

Predicted functions:

Term Confidence Notes
acetylcholinesterase activity 6.01557374116734 bayes_pls_golite062009
cholinesterase activity 3.53190978140684 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.29226913183273 bayes_pls_golite062009
triglyceride lipase activity 2.74157075059569 bayes_pls_golite062009
laminin-1 binding 2.61620056180634 bayes_pls_golite062009
choline binding 2.44944581139315 bayes_pls_golite062009
acetylcholine binding 2.15366394064412 bayes_pls_golite062009
carboxylesterase activity 2.10340684157921 bayes_pls_golite062009
lipase activity 1.95656432876646 bayes_pls_golite062009
hydrolase activity 1.89798820741335 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 1.63586830236611 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
sterol esterase activity 1.21262745914703 bayes_pls_golite062009
binding 0.978846093152455 bayes_pls_golite062009
phospholipase A1 activity 0.952103709202781 bayes_pls_golite062009
peptidase activity 0.946698616106528 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.92549140936125 bayes_pls_golite062009
protein binding 0.890384359682543 bayes_pls_golite062009
receptor binding 0.845720597560984 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.786172015267385 bayes_pls_golite062009
serine hydrolase activity 0.527527404338 bayes_pls_golite062009
acylglycerol lipase activity 0.345658974420231 bayes_pls_golite062009
serine-type peptidase activity 0.33062249657108 bayes_pls_golite062009
phospholipase activity 0.1336535306364 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.105057344027402 bayes_pls_golite062009
juvenile hormone epoxide hydrolase activity 0.0481017624758091 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [798-934]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHHQLHDDDD EDNNIPSDAS VKPLNPPYIS RAANAAAMAN FTIFTNQVFS LLNLSSPSSS  60
   61 LQRNGTRYGG GKIYPDDMMD GDHAGGAASA SQDSDGFAAY STALSVTIAI GCSLLILNVL 120
  121 IFAGVYYQRD KTRLSEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [935-1056]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPQTKLKRQE NGQMPNNICG DLETLTIHAK SDPATILSHH HAMQHHQLPP PEFADIPHRA  60
   61 PPPPKHMKSL QDPGGGGSVS GAVGVSGVVQ MPPPHALQVM GNQCGTLTKK SCMKQTQAQA 120
  121 QQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1057-1148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSPAQQQQQQ QQQQQQHVVT HQQHLQNHHN QSMTTVLTTA GGLVVPTPPT VPVIVASTTQ  60
   61 HQQHQQQHQQ QQHQQQQQQQ QQQHPLMDEL RV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle