YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1082336, gi\|5...
Organism:	Homo sapiens
Length:	707 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1082336, gi|5....

Description	E-value	Query Range	Subject Range
gi\|114623636 - gi\|114623636\|ref\|XP_001135994.1\| PREDICTED: regulatory factor X3 isoform 2 [Pan troglodytes]	900.0	[0..1]	[707..1]
gi\|73946688 - gi\|73946688\|ref\|XP_533540.2\| PREDICTED: similar to regulatory factor X3 isoform b isoform 1 [Canis f...	864.0	[0..1]	[660..1]
RFX3_MACFA - Transcription factor RFX3 OS=Macaca fascicularis GN=RFX3 PE=2 SV=1	862.0	[0..1]	[660..1]
gi\|109111667 - gi\|109111667\|ref\|XP_001086729.1\| PREDICTED: similar to regulatory factor X3 isoform b isoform 6 [Mac...	862.0	[0..1]	[660..1]
RFX3 - regulatory factor X, 3 (influences HLA class II expression)	861.0	[0..1]	[660..1]
RFX3_MOUSE - Transcription factor RFX3 OS=Mus musculus GN=Rfx3 PE=1 SV=2	861.0	[0..1]	[660..1]
gi\|111305724 - gi\|111305724\|gb\|AAI21501.1\| Rfx3 protein [Xenopus tropicalis]	832.0	[0..1]	[660..35]

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Predicted Domain #1

Region A:
Residues: [1-172]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTSETGSDT GSTVTLQTSV ASQAAVPTQV VQQVPVQQQV QQVQTVQQVQ HVYPAQVQYV  60
   61 EGSDTVYTNG AIRTTTYPYT ETQMYSQNTG GNYFDTQGSS AQVTTVVSSH SMVGTGGIQM 120
  121 GVTGGQLISS SGGTYLIGNS MENSGHSVTH TTRASPATIE MAIETLQKSD GL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	91.055517
Match:	PF04589.3
Description:	No description for PF04589.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [173-325]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STHRSSLLNS HLQWLLDNYE TAEGVSLPRS TLYNHYLRHC QEHKLDPVNA ASFGKLIRSI  60
   61 FMGLRTRRLG TRGNSKYHYY GIRVKPDSPL NRLQEDMQYM AMRQQPMQQK QRYKPMQKVD 120
  121 GVADGFTGSG QQTGTSVEQT VIAQSQHHQQ FLD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.522879
Match:	1dp7P
Description:	Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [326-401]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASRALPEFGE VEISSLPDGT TFEDIKSLQS LYREHCEAIL DVVVNLQFSL IEKLWQTFWR  60
   61 YSPSTPTDGT TITESS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [402-608]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSEIESRLP KAKLITLCKH ESILKWMCNC DHGMYQALVE ILIPDVLRPI PSALTQAIRN  60
   61 FAKSLEGWLS NAMNNIPQRM IQTKVAAVSA FAQTLRRYTS LNHLAQAARA VLQNTSQINQ 120
  121 MLSDLNRVDF ANVQEQASWV CQCDDNMVQR LETDFKMTLQ QQSTLEQWAA WLDNVMMQAL 180
  181 KPYEGRPSFP KAARQFLLKW SFYSSMV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [609-707]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRDLTLRSAA SFGSFHLIRL LYDEYMFYLV EHRVAQATGE TPIAVMGEVR EAERAVTHWV  60
   61 IKNKPELHFS LNTLLIKTMV PNQVSLRARR DCGVIARVP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.969	N/A	N/A	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits