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View Structure Prediction Details

Protein: gi|1082336, gi|5...
Organism: Homo sapiens
Length: 707 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1082336, gi|5....

Description E-value Query
Range
Subject
Range
gi|114623636 - gi|114623636|ref|XP_001135994.1| PREDICTED: regulatory factor X3 isoform 2 [Pan troglodytes]
900.0 [0..1] [707..1]
gi|73946688 - gi|73946688|ref|XP_533540.2| PREDICTED: similar to regulatory factor X3 isoform b isoform 1 [Canis f...
864.0 [0..1] [660..1]
RFX3_MACFA - Transcription factor RFX3 OS=Macaca fascicularis GN=RFX3 PE=2 SV=1
862.0 [0..1] [660..1]
gi|109111667 - gi|109111667|ref|XP_001086729.1| PREDICTED: similar to regulatory factor X3 isoform b isoform 6 [Mac...
862.0 [0..1] [660..1]
RFX3 - regulatory factor X, 3 (influences HLA class II expression)
861.0 [0..1] [660..1]
RFX3_MOUSE - Transcription factor RFX3 OS=Mus musculus GN=Rfx3 PE=1 SV=2
861.0 [0..1] [660..1]
gi|111305724 - gi|111305724|gb|AAI21501.1| Rfx3 protein [Xenopus tropicalis]
832.0 [0..1] [660..35]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTSETGSDT GSTVTLQTSV ASQAAVPTQV VQQVPVQQQV QQVQTVQQVQ HVYPAQVQYV  60
   61 EGSDTVYTNG AIRTTTYPYT ETQMYSQNTG GNYFDTQGSS AQVTTVVSSH SMVGTGGIQM 120
  121 GVTGGQLISS SGGTYLIGNS MENSGHSVTH TTRASPATIE MAIETLQKSD GL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 91.055517
Match: PF04589.3
Description: No description for PF04589.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [173-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STHRSSLLNS HLQWLLDNYE TAEGVSLPRS TLYNHYLRHC QEHKLDPVNA ASFGKLIRSI  60
   61 FMGLRTRRLG TRGNSKYHYY GIRVKPDSPL NRLQEDMQYM AMRQQPMQQK QRYKPMQKVD 120
  121 GVADGFTGSG QQTGTSVEQT VIAQSQHHQQ FLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 1dp7P
Description: Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [326-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASRALPEFGE VEISSLPDGT TFEDIKSLQS LYREHCEAIL DVVVNLQFSL IEKLWQTFWR  60
   61 YSPSTPTDGT TITESS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.781 a.118.8 TPR-like
View Download 0.756 a.118.8 TPR-like
View Download 0.748 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.743 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.714 a.118.8 TPR-like
View Download 0.639 a.8.11 Description not found.
View Download 0.629 a.8.11 Description not found.
View Download 0.553 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.523 a.112.1 Description not found.
View Download 0.521 a.112.1 Description not found.
View Download 0.430 a.59.1 PAH2 domain
View Download 0.411 a.4.1 Homeodomain-like
View Download 0.332 a.4.12 TrpR-like
View Download 0.321 a.16.1 S15/NS1 RNA-binding domain
View Download 0.306 d.58.4 Dimeric alpha+beta barrel

Predicted Domain #4
Region A:
Residues: [402-608]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSEIESRLP KAKLITLCKH ESILKWMCNC DHGMYQALVE ILIPDVLRPI PSALTQAIRN  60
   61 FAKSLEGWLS NAMNNIPQRM IQTKVAAVSA FAQTLRRYTS LNHLAQAARA VLQNTSQINQ 120
  121 MLSDLNRVDF ANVQEQASWV CQCDDNMVQR LETDFKMTLQ QQSTLEQWAA WLDNVMMQAL 180
  181 KPYEGRPSFP KAARQFLLKW SFYSSMV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [609-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRDLTLRSAA SFGSFHLIRL LYDEYMFYLV EHRVAQATGE TPIAVMGEVR EAERAVTHWV  60
   61 IKNKPELHFS LNTLLIKTMV PNQVSLRARR DCGVIARVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.969 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.929 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.798 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.793 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.779 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.758 N/A N/A a.2.17 Description not found.
View Download 0.726 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.670 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.608 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.501 N/A N/A a.8.9 Description not found.
View Download 0.380 N/A N/A d.68.8 Description not found.
View Download 0.327 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.279 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.252 N/A N/A d.52.7 Ribosome-binding factor A, RbfA


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle