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View Structure Prediction Details

Protein: TRIM2, TRMT2B
Organism: Homo sapiens
Length: 744 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRIM2, TRMT2B.

Description E-value Query
Range
Subject
Range
gi|23128312, gi|... - gi|23128312|ref|ZP_00110163.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668169...
5.0E-91 [286..741] [626..1089]
gi|37521534, gi|... - gi|37521534|ref|NP_924911.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35212...
1.0E-89 [254..743] [604..1101]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
2.0E-89 [213..743] [902..1440]
gi|75908842, gi|... - gi|75908842|ref|YP_323138.1| Fis family transcriptional regulator [Anabaena variabilis ATCC 29413], ...
8.0E-89 [286..742] [623..1051]
gi|116200089, gi... - gi|88179479|gb|EAQ86947.1| hypothetical protein CHGG_08200 [Chaetomium globosum CBS 148.51], gi|1162...
6.0E-88 [227..741] [921..1443]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEGTNIPS PVVRQIDKQF LICSICLERY KNPKVLPCLH TFCERCLQNY IPAHSLTLSC  60
   61 PVCRQTSILP EKGVAALQNN FFITNLMDVL QRTPGSNAEE SSILETVTAV AAGKPLSCPN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 2cklB
Description: No description for 2cklB was found.

Predicted Domain #2
Region A:
Residues: [121-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDGNVMEFYC QSCETAMCRE CTEGEHAEHP TVPLKDVVEQ HKASLQVQLD AVNKRLPEID  60
   61 SALQFISEII HQLTNQKASI VDDIHSTFDE LQKTLNVRKS VLLMELEVNY G

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.54
Match: 2djaA
Description: No description for 2djaA was found.

Predicted functions:

Term Confidence Notes
binding 1.40795253804896 bayes_pls_golite062009
protein binding 1.25958462602675 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [232-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKHKVLQSQL DTLLQGQESI KSCSNFTAQA LNHGTETEVL LVKKQMSEKL NELADQDFPL  60
   61 HPRENDQLDF I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [303-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VETEGLKKSI HNLGTILTTN AVASETVATG EGLRQTIIGQ PMSVTITTKD KDGELCKTGN  60
   61 AYLTAELSTP DGSVADGEIL DNKNGTYEFL YTVQKEGDFT LSLRLYDQHI RGSPFKLKVI 120
  121 RSADVSPTTE GVKRRVKSPG SGHVKQKAVK RPASMYSTGK RKENPIEDDL IFRVGTKGRN 180
  181 KGEFTNLQGV AASTNGKILI ADSNNQCVQI FSNDGQFKSR FGIRGRSPGQ LQRPTGVAVH 240
  241 PSGDIIIADY DNKWVSIFSS DGKFKTKIGS GKLMGPKGVS VDRNGHIIVV DNKACCVFIF 300
  301 QPNGKIVTRF GSRGNGDRQF AGPHFAAVNS NNEIIITDFH NHSVKVFNQE GEFMLKFGSN 360
  361 GEGNGQFNAP TGVAVDSNGN IIVADWGNSR IQVFDGSGSF LSYINTSADP LYGPQGLALT 420
  421 SDGHVVVADS GNHCFKVYRY LQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.09691
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.34904600386994 bayes_pls_golite062009
protein binding 1.24173112731149 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle