YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: TAS2R7
Organism: Homo sapiens
Length: 318 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAS2R7.

Description E-value Query
Range
Subject
Range
gi|73953906 - gi|73953906|ref|XP_853735.1| PREDICTED: similar to Opsin-4 (Melanopsin) [Canis familiaris]
1.0E-52 [6..304] [97..390]
gi|114602683 - gi|114602683|ref|XP_527068.2| PREDICTED: adrenergic, beta-2-, receptor, surface [Pan troglodytes]
4.0E-52 [4..308] [338..655]
OPN4_BRABE - Melanopsin OS=Branchiostoma belcheri GN=OPN4 PE=1 SV=1
8.0E-52 [2..311] [81..394]
gi|68370558 - gi|68370558|ref|XP_692751.1| PREDICTED: similar to Galanin receptor type 2 (GAL2-R) (GALR2) [Danio r...
3.0E-51 [4..302] [371..658]
gi|110764421 - gi|110764421|ref|XP_395084.3| PREDICTED: similar to Neuropeptide Y receptor-like CG5811-PA [Apis mel...
1.0E-49 [3..303] [379..678]
gi|21951818 - gi|21951818|gb|AAM82355.1|AF311307_1 somatostatin receptor type 3 [Carassius auratus]
2.0E-49 [7..316] [58..354]
gi|10121075, gi|... - gi|10121076|pdb|1F88|B Chain B, Crystal Structure Of Bovine Rhodopsin, gi|10121075|pdb|1F88|A Chain ...
3.0E-48 [3..313] [34..334]
OPSD1_MIZYE - Rhodopsin, GQ-coupled OS=Mizuhopecten yessoensis GN=SCOP1 PE=1 SV=1
4.0E-48 [4..317] [49..364]

Back

Predicted Domain #1
Region A:
Residues: [1-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKVQTTLL FLAVGEFSVG ILGNAFIGLV NCMDWVKKRK IASIDLILTS LAISRICLLC  60
   61 VILLDCFILV LYPDVYATGK EMRIIDFFWT LTNHLSIWFA TCLSIYYFFK IGNFFHPLFL 120
  121 WMKWRIDRVI SWILLGCVVL SVFISLPATE NLNADFRFCV KAKRKTNLTW SCRVNKTQHA 180
  181 STKLFLNLAT LLPFCVCLMS FFLLILSLRR HIRRMQLSAT GCRDPSTEAH VRALKAVISF 240
  241 LLLFIAYYLS FLIATSSYFM PETELAVIFG ESIALIYPSS HSFILILGNN KLRHASLKVI 300
  301 WKVMSILKGR KFQQHKQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 8.71814901383196 bayes_pls_golite062009
receptor activity 7.06055966221158 bayes_pls_golite062009
transmembrane receptor activity 7.01539599282724 bayes_pls_golite062009
peptide receptor activity, G-protein coupled 6.12541205240173 bayes_pls_golite062009
molecular transducer activity 6.05267963238754 bayes_pls_golite062009
signal transducer activity 6.05267963238754 bayes_pls_golite062009
peptide receptor activity 6.04856799440486 bayes_pls_golite062009
neuropeptide binding 5.46057090687513 bayes_pls_golite062009
neuropeptide receptor activity 5.46057090687513 bayes_pls_golite062009
neurotransmitter receptor activity 5.35616101960681 bayes_pls_golite062009
olfactory receptor activity 5.32566921415386 bayes_pls_golite062009
neurotransmitter binding 5.22191968259492 bayes_pls_golite062009
photoreceptor activity 4.88623417946763 bayes_pls_golite062009
peptide binding 4.8780653006611 bayes_pls_golite062009
G-protein coupled photoreceptor activity 4.74437083278777 bayes_pls_golite062009
G-protein coupled amine receptor activity 3.93706716877289 bayes_pls_golite062009
binding 2.36534865182258 bayes_pls_golite062009
tachykinin receptor activity 1.92904295303979 bayes_pls_golite062009
11-cis retinal binding 1.82770762956867 bayes_pls_golite062009
somatostatin receptor activity 1.6896410144458 bayes_pls_golite062009
protein-hormone receptor activity 1.64635966454507 bayes_pls_golite062009
opioid receptor activity 1.63541566951702 bayes_pls_golite062009
galanin receptor activity 0.89794875509843 bayes_pls_golite062009
cytokine binding 0.89442507280303 bayes_pls_golite062009
retinal binding 0.74510266827654 bayes_pls_golite062009
adrenoceptor activity 0.669607596430449 bayes_pls_golite062009
growth hormone secretagogue receptor activity 0.661292626326209 bayes_pls_golite062009
allatostatin receptor activity 0.57306858576999 bayes_pls_golite062009
amine binding 0.54996394505819 bayes_pls_golite062009
growth hormone-releasing hormone receptor activity 0.54640132962575 bayes_pls_golite062009
protein binding 0.516440306486999 bayes_pls_golite062009
peptide hormone binding 0.28920851380115 bayes_pls_golite062009
passive transmembrane transporter activity 0.242205396709226 bayes_pls_golite062009
channel activity 0.242205396709226 bayes_pls_golite062009
substrate-specific channel activity 0.220852744545477 bayes_pls_golite062009
receptor binding 0.210677048019125 bayes_pls_golite062009
ion channel activity 0.137820007538405 bayes_pls_golite062009
gated channel activity 0.121740107050698 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle