| Protein: | OPHN1 |
| Organism: | Homo sapiens |
| Length: | 802 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OPHN1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..802] | [1..802] |
|
|
0.0 | [1..802] | [1..802] |
|
|
0.0 | [1..802] | [1..802] |
|
|
0.0 | [1..802] | [1..802] |
|
|
0.0 | [1..802] | [1..802] |
|
|
0.0 | [1..796] | [1..816] |
|
Region A: Residues: [1-361] |
1 11 21 31 41 51
| | | | | |
1 MGHPPLEFSD CYLDSPDFRE RLKCYEQELE RTNKFIKDVI KDGNALISAM RNYSSAVQKF 60
61 SQTLQSFQFD FIGDTLTDDE INIAESFKEF AELLNEVENE RMMMVHNASD LLIKPLENFR 120
121 KEQIGFTKER KKKFEKDGER FYSLLDRHLH LSSKKKESQL QEADLQVDKE RHNFFESSLD 180
181 YVYQIQEVQE SKKFNIVEPV LAFLHSLFIS NSLTVELTQD FLPYKQQLQL SLQNTRNHFS 240
241 STREEMEELK KRMKEAPQTC KLPGQPTIEG YLYTQEKWAL GISWVKYYCQ YEKETKTLTM 300
301 TPMEQKPGAK QGPLDLTLKY CVRRKTESID KRFCFDIETN ERPGTITLQA LSEANRRLWM 360
361 E
|
| Detection Method: |  |
| Confidence: | 55.221849 |
| Match: | 2elbA |
| Description: | No description for 2elbA was found. |
| Term | Confidence | Notes |
| actin binding | 4.76659069034376 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.48744511411671 | bayes_pls_golite062009 |
| binding | 3.29080729281876 | bayes_pls_golite062009 |
| actin filament binding | 2.99963220150463 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| molecular transducer activity | 1.55319485371003 | bayes_pls_golite062009 |
| signal transducer activity | 1.55319485371003 | bayes_pls_golite062009 |
| profilin binding | 0.91195854193678 | bayes_pls_golite062009 |
| protein domain specific binding | 0.90578029954417 | bayes_pls_golite062009 |
| transporter activity | 0.882299675921716 | bayes_pls_golite062009 |
| receptor binding | 0.50127063593663 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.35466574267734 | bayes_pls_golite062009 |
| receptor activity | 0.353510125274044 | bayes_pls_golite062009 |
| transcription regulator activity | 0.324566338715835 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.276130226777911 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.2237168095091 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.207829786337892 | bayes_pls_golite062009 |
| DNA binding | 0.136435190086451 | bayes_pls_golite062009 |
| nucleic acid binding | 0.118897432176337 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.10105990547756 | bayes_pls_golite062009 |
|
Region A: Residues: [362-576] |
1 11 21 31 41 51
| | | | | |
1 AMDGKEPIYH SPITKQQEME LNEVGFKFVR KCINIIETKG IKTEGLYRTV GSNIQVQKLL 60
61 NAFFDPKCPG DVDFHNSDWD IKTITSSLKF YLRNLSEPVM TYRLHKELVS AAKSDNLDYR 120
121 LGAIHSLVYK LPEKNREMLE LLIRHLVNVC EHSKENLMTP SNMGVIFGPT LMRAQEDTVA 180
181 AMMNIKFQNI VVEILIEHFG KIYLGPPEES AAPPV
|
| Detection Method: | |
| Confidence: | 47.0 |
| Match: | 1f7cA |
| Description: | Graf |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| actin binding | 4.17357159737697 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.42802398019084 | bayes_pls_golite062009 |
| GTPase regulator activity | 3.22858435052736 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.20644605106099 | bayes_pls_golite062009 |
| GTPase activator activity | 3.18597454327808 | bayes_pls_golite062009 |
| microfilament motor activity | 2.96155001519594 | bayes_pls_golite062009 |
| enzyme activator activity | 2.92839426561878 | bayes_pls_golite062009 |
| enzyme regulator activity | 2.87900480746065 | bayes_pls_golite062009 |
| small GTPase regulator activity | 2.8055856880102 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 2.79506512079992 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 2.58359112320183 | bayes_pls_golite062009 |
| actin filament binding | 2.45667344398622 | bayes_pls_golite062009 |
| binding | 2.26769740280417 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 1.74529419104576 | bayes_pls_golite062009 |
| motor activity | 1.7327021907162 | bayes_pls_golite062009 |
| tubulin binding | 1.56332747753627 | bayes_pls_golite062009 |
| signal transducer activity | 1.42814294153578 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42814294153578 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 1.35032386782255 | bayes_pls_golite062009 |
| protein binding | 1.21496582666968 | bayes_pls_golite062009 |
| microtubule binding | 0.648232426961013 | bayes_pls_golite062009 |
| ADP binding | 0.56346827542888 | bayes_pls_golite062009 |
| transcription regulator activity | 0.534597007915358 | bayes_pls_golite062009 |
| receptor activity | 0.434186339265983 | bayes_pls_golite062009 |
| nucleic acid binding | 0.400842733744238 | bayes_pls_golite062009 |
| Rho GTPase binding | 0.33949271618205 | bayes_pls_golite062009 |
| DNA binding | 0.313042678225127 | bayes_pls_golite062009 |
|
Region A: Residues: [577-802] |
1 11 21 31 41 51
| | | | | |
1 PPPRVTARRH KPITISKRLL RERTVFYTSS LDESEDEIQH QTPNGTITSS IEPPKPPQHP 60
61 KLPIQRSGET DPGRKSPSRP ILDGKLEPCP EVDVGKLVSR LQDGGTKITP KATNGPMPGS 120
121 GPTKTPSFHI KRPAPRPLAH HKEGDADSFS KVRPPGEKPT IIRPPVRPPD PPCRAATPQK 180
181 PEPKPDIVAG NAGEITSSVV ASRTRFFETA SRKTGSSQGR LPGDES
|
| Detection Method: | |
| Confidence: | 3.69897 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
