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View Structure Prediction Details

Protein: gi|29735974
Organism: Homo sapiens
Length: 128 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29735974.

Description E-value Query
Range
Subject
Range
gi|68432331 - gi|68432331|ref|XP_690287.1| PREDICTED: similar to ReO_6 [Danio rerio]
2.0E-52 [1..126] [288..411]
gi|114595343 - gi|114595343|ref|XP_517363.2| PREDICTED: hypothetical protein [Pan troglodytes]
3.0E-48 [2..128] [272..398]
gi|109066680 - gi|109066680|ref|XP_001093992.1| PREDICTED: similar to H2A histone family, member V isoform 1 [Macac...
8.0E-48 [1..127] [187..313]
gi|74004252 - gi|74004252|ref|XP_545426.2| PREDICTED: similar to Histone H2A.l (H2A/l) [Canis familiaris]
3.0E-47 [1..125] [50..172]
gi|109500010 - gi|109500010|ref|XP_001065720.1| PREDICTED: similar to H2A histone family, member V isoform 1 [Rattu...
5.0E-47 [1..127] [136..262]
gi|76612869 - gi|76612869|ref|XP_871733.1| PREDICTED: similar to histone H2A [Bos taurus]
2.0E-46 [1..127] [61..185]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGGKAGKDS GKAKTKAVSR CQRAGLQFPV GRIHLHLKSR TTNHGRVGAT AAVYSAAILK  60
   61 YLTAEVLELA GNASKDLKVK RSTTGHLQLA IRGDEELDSL IKATIAGGGV IPHIHKSLTG 120
  121 KKGQQKTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1f66C
Description: Histone H2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 4.57339366278729 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.71983173426562 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
DNA binding 2.84801656088633 bayes_pls_golite062009
nucleic acid binding 2.73664032839239 bayes_pls_golite062009
transcription regulator activity 2.30478015157761 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.21819833304707 bayes_pls_golite062009
protein binding 1.07873333188144 bayes_pls_golite062009
centromeric DNA binding 1.03586371237592 bayes_pls_golite062009
transcription factor activity 1.01889555697279 bayes_pls_golite062009
transcription initiation factor activity 0.725138319268162 bayes_pls_golite062009
transferase activity 0.424228486183795 bayes_pls_golite062009
histone binding 0.218942897869955 bayes_pls_golite062009
transcription factor binding 0.20278000165075 bayes_pls_golite062009
transcription activator activity 0.16305156761639 bayes_pls_golite062009
transcription cofactor activity 0.0427278296123499 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle