| Protein: | SMN2, SMN1 |
| Organism: | Homo sapiens |
| Length: | 294 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMN2, SMN1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..294] | [1..294] |
|
|
0.0 | [2..294] | [1..293] |
|
|
0.0 | [1..294] | [1..294] |
|
|
0.0 | [1..294] | [1..297] |
|
|
0.0 | [10..291] | [1..281] |
|
|
0.0 | [12..291] | [8..285] |
|
|
0.0 | [1..291] | [1..288] |
|
Region A: Residues: [1-72] |
1 11 21 31 41 51
| | | | | |
1 MAMSSGGSGG GVPEQEDSVL FRRGTGQSDD SDIWDDTALI KAYDKAVASF KHALKNGDIC 60
61 ETSGKPKTTP KR
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.229 | 0.074 | spliceosome assembly | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.235 | 0.008 | spliceosome assembly | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.227 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
|
Region A: Residues: [73-166] |
1 11 21 31 41 51
| | | | | |
1 KPAKKNKSQK KNTAASLQQW KVGDKCSAIW SEDGCIYPAT IASIDFKRET CVVVYTGYGN 60
61 REEQNLSDLL SPICEVANNI EQNAQENENE SQVS
|
| Detection Method: | |
| Confidence: | 28.30103 |
| Match: | 1g5vA |
| Description: | Survival motor neuron protein 1, smn |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.8914433770482 | bayes_pls_golite062009 |
| transcription regulator activity | 2.23645140702533 | bayes_pls_golite062009 |
| protein binding | 1.97653343528228 | bayes_pls_golite062009 |
| DNA binding | 1.38254179968032 | bayes_pls_golite062009 |
| nucleic acid binding | 1.29663886491206 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.85415557686977 | bayes_pls_golite062009 |
| transcription repressor activity | 0.81676066297927 | bayes_pls_golite062009 |
| transcription factor binding | 0.77325691466894 | bayes_pls_golite062009 |
| transcription factor activity | 0.567394926956068 | bayes_pls_golite062009 |
| N-methyltransferase activity | 0.53946303154276 | bayes_pls_golite062009 |
| chromatin binding | 0.25107231011304 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 0.223495463070134 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.21258120552184 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.0304922925916231 | bayes_pls_golite062009 |
| histone binding | 0.0149490634137095 | bayes_pls_golite062009 |
|
Region A: Residues: [167-294] |
1 11 21 31 41 51
| | | | | |
1 TDESENSRSP GNKSDNIKPK SAPWNSFLPP PPPMPGPRLG PGKPGLKFNG PPPPPPPPPP 60
61 HLLSCWLPPF PSGPPIIPPP PPICPDSLDD ADALGSMLIS WYMSGYHTGY YMGFRQNQKE 120
121 GRCSHSLN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
