| Protein: | MBD3 |
| Organism: | Homo sapiens |
| Length: | 291 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MBD3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..291] | [1..291] |
|
|
0.0 | [1..267] | [1..267] |
|
|
0.0 | [1..291] | [1..291] |
|
|
0.0 | [1..260] | [1..260] |
|
|
0.0 | [1..262] | [1..262] |
|
|
0.0 | [1..270] | [1..269] |
|
Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MERKRWECPA LPQGWEREEV PRRSGLSAGH RDVFYYSPSG KKFRSKPQLA RYLGGSMDLS 60
61 TFDFRTGKML MSKMNKSR
|
| Detection Method: |  |
| Confidence: | 26.522879 |
| Match: | 1d9nA |
| Description: | Methylation-dependent transcriptional repressor MBD1/PCM1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| methyl-CpG binding | 4.54540676267869 | bayes_pls_golite062009 |
| DNA binding | 4.42562920230852 | bayes_pls_golite062009 |
| nucleic acid binding | 4.33195028920652 | bayes_pls_golite062009 |
| double-stranded methylated DNA binding | 4.13704647712557 | bayes_pls_golite062009 |
| unmethylated CpG binding | 4.11290155206252 | bayes_pls_golite062009 |
| transcription repressor activity | 3.19559870959168 | bayes_pls_golite062009 |
| binding | 3.0325775548747 | bayes_pls_golite062009 |
| chromatin binding | 2.99247237408109 | bayes_pls_golite062009 |
| transcription regulator activity | 2.97633361410339 | bayes_pls_golite062009 |
| transcription corepressor activity | 2.70291730403476 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.42722575436746 | bayes_pls_golite062009 |
| transcription factor activity | 2.27540830787547 | bayes_pls_golite062009 |
| transcription factor binding | 1.67549684739333 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.53919976183276 | bayes_pls_golite062009 |
| protein binding | 1.48651016577672 | bayes_pls_golite062009 |
| DNA secondary structure binding | 1.40804604506756 | bayes_pls_golite062009 |
| four-way junction DNA binding | 1.09532938985367 | bayes_pls_golite062009 |
| nucleotide binding | 0.409742306544047 | bayes_pls_golite062009 |
| RNA binding | 0.33612198087066 | bayes_pls_golite062009 |
| mRNA binding | 0.28477406293958 | bayes_pls_golite062009 |
|
Region A: Residues: [79-196] |
1 11 21 31 41 51
| | | | | |
1 QRVRYDSSNQ VKGKPDLNTA LPVRQTASIF KQPVTKITNH PSNKVKSDPQ KAVDQPRQLF 60
61 WEKKLSGLNA FDIAEELVKT MDLPKGLQGV GPGCTDETLL SAIASALHTS TMPITGQL
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [197-291] |
1 11 21 31 41 51
| | | | | |
1 SAAVEKNPGV WLNTTQPLCK AFMVTDEDIR KQEELVQQVR KRLEEALMAD MLAHVEELAR 60
61 DGEAPLDKAC AEDDDEEDEE EEEEEPDPDP EMEHV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
