| Protein: | PFKFB1 |
| Organism: | Homo sapiens |
| Length: | 471 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFKFB1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..471] | [1..471] |
|
|
0.0 | [1..471] | [1..471] |
|
|
0.0 | [1..471] | [119..589] |
|
|
0.0 | [1..471] | [1..471] |
|
|
0.0 | [1..471] | [1..471] |
|
|
0.0 | [1..471] | [1..470] |
|
|
0.0 | [5..471] | [4..469] |
|
Region A: Residues: [1-471] |
1 11 21 31 41 51
| | | | | |
1 MSPEMGELTQ TRLQKIWIPH SSGSSRLQRR RGSSIPQFTN SPTMVIMVGL PARGKTYIST 60
61 KLTRYLNWIG TPTKVFNLGQ YRREAVSYKN YEFFLPDNME ALQIRKQCAL AALKDVHNYL 120
121 SHEEGHVAVF DATNTTRERR SLILQFAKEH GYKVFFIESI CNDPGIIAEN IRQVKLGSPD 180
181 YIDCDREKVL EDFLKRIECY EVNYQPLDEE LDSHLSYIKI FDVGTRYMVN RVQDHIQSRT 240
241 VYYLMNIHVT PRSIYLCRHG ESELNIRGRI GGDSGLSVRG KQYAYALANF IQSQGISSLK 300
301 VWTSHMKRTI QTAEALGVPY EQWKALNEID AGVCEEMTYE EIQEHYPEEF ALRDQDKYRY 360
361 RYPKGESYED LVQRLEPVIM ELERQENVLV ICHQAVMRCL LAYFLDKSSD ELPYLKCPLH 420
421 TVLKLTPVAY GCKVESIYLN VEAVNTHREK PENVDITREP EEALDTVPAH Y
|
| Detection Method: |  |
| Confidence: | 159.0 |
| Match: | 3bifA |
| Description: | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 6-phosphofructo-2-kinase activity | 5.42792629395033 | bayes_pls_golite062009 |
| fructose-2,6-bisphosphate 2-phosphatase activity | 5.3758259177501 | bayes_pls_golite062009 |
| phosphofructokinase activity | 4.74681837647377 | bayes_pls_golite062009 |
| phosphoglycerate mutase activity | 3.38777226675734 | bayes_pls_golite062009 |
| fructose binding | 2.65431677206223 | bayes_pls_golite062009 |
| fructose-6-phosphate binding | 2.61827203165744 | bayes_pls_golite062009 |
| phosphatase activity | 2.20711859657073 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.0220580269993 | bayes_pls_golite062009 |
| carbohydrate kinase activity | 1.86382423322759 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.78167518994202 | bayes_pls_golite062009 |
| kinase activity | 1.67050219347378 | bayes_pls_golite062009 |
| carbohydrate phosphatase activity | 1.56016941506609 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.3848751235482 | bayes_pls_golite062009 |
| catalytic activity | 1.37714494241232 | bayes_pls_golite062009 |
| hydrolase activity | 1.32674664996211 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 1.24295845488314 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.08151102259045 | bayes_pls_golite062009 |
| nucleic acid binding | 0.974702705020209 | bayes_pls_golite062009 |
| intramolecular transferase activity, phosphotransferases | 0.916759493094631 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.867181425037322 | bayes_pls_golite062009 |
| binding | 0.864238150099353 | bayes_pls_golite062009 |
| transferase activity | 0.709223678750312 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.688993364310212 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.656009904481476 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.64416740142962 | bayes_pls_golite062009 |
| GTP binding | 0.643084645864898 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.561773791863863 | bayes_pls_golite062009 |
| DNA binding | 0.522586598136164 | bayes_pls_golite062009 |
| GTPase activity | 0.406399103964327 | bayes_pls_golite062009 |
| isomerase activity | 0.275500708652009 | bayes_pls_golite062009 |
| transcription regulator activity | 0.261132792329283 | bayes_pls_golite062009 |
| protein binding | 0.236742803345453 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.141310691160109 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.0935614991493088 | bayes_pls_golite062009 |
| protein kinase activity | 0.0646123847220056 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0137537621821964 | bayes_pls_golite062009 |
