| Protein: | ETS1 |
| Organism: | Homo sapiens |
| Length: | 441 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ETS1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..441] | [1..441] |
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0.0 | [1..441] | [1..441] |
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0.0 | [1..441] | [1..441] |
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0.0 | [1..441] | [1..441] |
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0.0 | [1..440] | [1..440] |
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|
0.0 | [1..441] | [1..441] |
|
|
0.0 | [1..441] | [1..441] |
|
Region A: Residues: [1-141] |
1 11 21 31 41 51
| | | | | |
1 MKAAVDLKPT LTIIKTEKVD LELFPSPDME CADVPLLTPS SKEMMSQALK ATFSGFTKEQ 60
61 QRLGIPKDPR QWTETHVRDW VMWAVNEFSL KGVDFQKFCM NGAALCALGK DCFLELAPDF 120
121 VGDILWEHLE ILQKEDVKPY Q
|
| Detection Method: |  |
| Confidence: | 40.0 |
| Match: | 2jv3A |
| Description: | No description for 2jv3A was found. |
|
Region A: Residues: [142-205] |
1 11 21 31 41 51
| | | | | |
1 VNGVNPAYPE SRYTSDYFIS YGIEHAQCVP PSEFSEPSFI TESYQTLHPI SSEELLSLKY 60
61 ENDY
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.487 | a.77.1 | DEATH domain |
| View | Download | 0.432 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.456 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.441 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.412 | a.76.1 | Iron-dependent represor protein, dimerization domain |
|
Region A: Residues: [206-441] |
1 11 21 31 41 51
| | | | | |
1 PSVILRDPLQ TDTLQNDYFA IKQEVVTPDN MCMGRTSRGK LGGQDSFESI ESYDSCDRLT 60
61 QSWSSQSSFN SLQRVPSYDS FDSEDYPAAL PNHKPKGTFK DYVRDRADLN KDKPVIPAAA 120
121 LAGYTGSGPI QLWQFLLELL TDKSCQSFIS WTGDGWEFKL SDPDEVARRW GKRKNKPKMN 180
181 YEKLSRGLRY YYDKNIIHKT AGKRYVYRFV CDLQSLLGYT PEELHAMLDV KPDADE
|
| Detection Method: | |
| Confidence: | 57.30103 |
| Match: | 1mdmB |
| Description: | ETS-1 transcription factor, residues 331-440 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| transcription activator activity | 3.70589483230587 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.58179858678904 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.60738445921725 | bayes_pls_golite062009 |
| transcription repressor activity | 2.22485867684613 | bayes_pls_golite062009 |
| protein binding | 1.80415286835431 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.2723726467408 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.66743181561551 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.23177057841536 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.0565989703351002 | bayes_pls_golite062009 |
