| Protein: | BRF1 |
| Organism: | Homo sapiens |
| Length: | 677 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BRF1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..677] | [1..676] |
|
|
0.0 | [1..677] | [1..676] |
|
|
0.0 | [1..677] | [1..675] |
|
|
5.0E-97 | [56..677] | [198..819] |
|
|
2.0E-92 | [62..677] | [22..637] |
|
|
4.0E-92 | [1..675] | [1..659] |
|
|
3.0E-89 | [6..677] | [4..661] |
|
Region A: Residues: [1-290] |
1 11 21 31 41 51
| | | | | |
1 MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL 60
61 DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR 120
121 HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVNV YVLGKTFLLL ARELCINAPA 180
181 IDPCLYIPRF AHLLEFGEKN HEVSMTALRL LQRMKRDWMH TGRRPSGLCG AALLVAARMH 240
241 DFRRTVKEVI SVVKVCESTL RKRLTEFEDT PTSQLTIDEF MKIDLEEECD
|
| Detection Method: |  |
| Confidence: | 37.154902 |
| Match: | 2g9xB |
| Description: | No description for 2g9xB was found. |
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 6.34389570239956 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase regulator activity | 3.19553060844126 | bayes_pls_golite062009 |
| protein kinase regulator activity | 2.87088741581791 | bayes_pls_golite062009 |
| transcription regulator activity | 2.795846725429 | bayes_pls_golite062009 |
| binding | 2.4204867358489 | bayes_pls_golite062009 |
| nucleic acid binding | 2.04886889839181 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.00665312545368 | bayes_pls_golite062009 |
| DNA binding | 1.94297811210385 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 1.69439693414478 | bayes_pls_golite062009 |
| kinase regulator activity | 1.65109787211976 | bayes_pls_golite062009 |
| protein binding | 1.47106731485576 | bayes_pls_golite062009 |
| transcription factor activity | 1.21921365719206 | bayes_pls_golite062009 |
| RNA binding | 1.02001545745027 | bayes_pls_golite062009 |
| transcription factor binding | 0.749278791251235 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.729629809946521 | bayes_pls_golite062009 |
| positive transcription elongation factor activity | 0.42590121577004 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.138191616709499 | bayes_pls_golite062009 |
| transcription activator activity | 0.0696060248241566 | bayes_pls_golite062009 |
|
Region A: Residues: [291-385] |
1 11 21 31 41 51
| | | | | |
1 PPSYTAGQRK LRMKQLEQVL SKKLEEVEGE ISSYQDAIEI ELENSRPKAK GGLASLAKDG 60
61 STEDTASSLC GEEDTEDEEL EAAASHLNKD LYREL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.818 | a.64.1 | Saposin |
|
Region A: Residues: [386-489] |
1 11 21 31 41 51
| | | | | |
1 LGGAPGSSEA AGSPEWGGRP PALGSLLDPL PTAASLGISD SIRECISSQS SDPKDASGDG 60
61 ELDLSGIDDL EIDRYILNES EARVKAELWM RENAEYLREQ REKE
|
| Detection Method: | |
| Confidence: | 2.69 |
| Match: | 1ngmB |
| Description: | TBP-binding domain of the transcription factor IIIb Brf1 subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [490-677] |
1 11 21 31 41 51
| | | | | |
1 ARIAKEKELG IYKEHKPKKS CKRREPIQAS TAREAIEKML EQKKISSKIN YSVLRGLSSA 60
61 GGGSPHREDA QPEHSASARK LSRRRTPASR SGADPVTSVG KRLRPLVSTQ PAKKVATGEA 120
121 LLPSSPTLGA EPARPQAVLV ESGPVSYHAD EEADEEEPDE EDGEPCVSAL QMMGSNDYGC 180
181 DGDEDDGY
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
