| Protein: | SPTLC2 |
| Organism: | Homo sapiens |
| Length: | 562 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPTLC2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..562] | [1..560] |
|
|
0.0 | [1..562] | [48..609] |
|
|
0.0 | [1..562] | [1..560] |
|
|
0.0 | [1..562] | [334..893] |
|
|
0.0 | [1..562] | [1..560] |
|
|
0.0 | [1..562] | [130..691] |
|
|
0.0 | [1..562] | [116..677] |
|
|
1.0E-99 | [1..552] | [107..655] |
|
Region A: Residues: [1-122] |
1 11 21 31 41 51
| | | | | |
1 MRPEPGGCCC RRTVRANGCV ANGEVRNGYV RSSAAAAAAA AAGQIHHVTQ NGGLYKRPFN 60
61 EAFEETPMLV AVLTYVGYGV LTLFGYLRDF LRYWRIEKCH HATEREEQKD FVSLYQDFEN 120
121 FY
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [123-562] |
1 11 21 31 41 51
| | | | | |
1 TRNLYMRIRD NWNRPICSVP GARVDIMERQ SHDYNWSFKY TGNIIKGVIN MGSYNYLGFA 60
61 RNTGSCQEAA AKVLEEYGAG VCSTRQEIGN LDKHEELEEL VARFLGVEAA MAYGMGFATN 120
121 SMNIPALVGK GCLILSDELN HASLVLGARL SGATIRIFKH NNMQSLEKLL KDAIVYGQPR 180
181 TRRPWKKILI LVEGIYSMEG SIVRLPEVIA LKKKYKAYLY LDEAHSIGAL GPTGRGVVEY 240
241 FGLDPEDVDV MMGTFTKSFG ASGGYIGGKK ELIDYLRTHS HSAVYATSLS PPVVEQIITS 300
301 MKCIMGQDGT SLGKECVQQL AENTRYFRRR LKEMGFIIYG NEDSPVVPLM LYMPAKIGAF 360
361 GREMLKRNIG VVVVGFPATP IIESRARFCL SAAHTKEILD TALKEIDEVG DLLQLKYSRH 420
421 RLVPLLDRPF DETTYEETED
|
| Detection Method: | |
| Confidence: | 62.69897 |
| Match: | 1fc4A |
| Description: | 2-amino-3-ketobutyrate CoA ligase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| serine C-palmitoyltransferase activity | 9.1839236553858 | bayes_pls_golite062009 |
| C-palmitoyltransferase activity | 9.1839236553858 | bayes_pls_golite062009 |
| C-acyltransferase activity | 4.29379571948906 | bayes_pls_golite062009 |
| 5-aminolevulinate synthase activity | 3.15163480353521 | bayes_pls_golite062009 |
| L-aspartate:2-oxoglutarate aminotransferase activity | 2.82458180884712 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| N-succinyltransferase activity | 1.81799375593294 | bayes_pls_golite062009 |
| threonine aldolase activity | 1.80396420390785 | bayes_pls_golite062009 |
| adenosylmethionine-8-amino-7-oxononanoate transaminase activity | 1.74778109525713 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 1.46601963907552 | bayes_pls_golite062009 |
| glycine dehydrogenase (decarboxylating) activity | 1.46601963907552 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| transcription regulator activity | 1.07873942461292 | bayes_pls_golite062009 |
| glycine C-acetyltransferase activity | 0.935794708043259 | bayes_pls_golite062009 |
| DNA binding | 0.886628214497634 | bayes_pls_golite062009 |
| nucleic acid binding | 0.814403324199462 | bayes_pls_golite062009 |
| structural molecule activity | 0.811208803619077 | bayes_pls_golite062009 |
| transferase activity | 0.737426388870721 | bayes_pls_golite062009 |
| carbon-sulfur lyase activity | 0.698312655247044 | bayes_pls_golite062009 |
| binding | 0.661198018681765 | bayes_pls_golite062009 |
| intramolecular transferase activity, transferring amino groups | 0.659071155545801 | bayes_pls_golite062009 |
| transcription factor activity | 0.615294010373048 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 0.319452731970428 | bayes_pls_golite062009 |
| cystathionine beta-lyase activity | 0.15938456446406 | bayes_pls_golite062009 |
| sulfurtransferase activity | 0.0450490929307473 | bayes_pls_golite062009 |
