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View Structure Prediction Details

Protein: SAF1
Organism: Saccharomyces cerevisiae
Length: 637 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAF1.

Description E-value Query
Range
Subject
Range
SAF1 - F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quies...
517.0 [0..1] [637..6]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVESREKE PDAGLSPDIV QATLPFLSSD DIKNLSQTNK YYNTLLDFDH SKILWHELFH  60
   61 KAFGTLKTND EPFQGRNSAE FKTCTETILR EAFPTLSWQE VYQLRAYDAK FYSWGYLKHG 120
  121 RLGYTASSNN ELVATSLNGP SPRFKYGVNT PTEVPWFNSR TTSRTSNFTP SEDPLSAIKK 180
  181 DGDEIIAQVS SGGFSFQILT ESGNLYSSGS TFSGGLKGPG PSGSQHDYNP FREMIHNMER 240
  241 SYPRITSRSN GSTVNTTGTF SGRRMSG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1a12A
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.01485857731423 bayes_pls_golite062009
small conjugating protein ligase activity 4.93236158049022 bayes_pls_golite062009
acid-amino acid ligase activity 4.21249056267986 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.40166727602209 bayes_pls_golite062009
ligase activity 1.84832719690603 bayes_pls_golite062009
binding 0.720895345637233 bayes_pls_golite062009
catalytic activity 0.277477143337075 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [268-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHPSTAYEPG NATTAQHITI DSGGAPAASP GGSHSGVPRT TMPSMGPHEN IYSQIEMLER  60
   61 SANKAVPGNN HIRRMFARNS FPLYSGRDEN LGSFNDIQFV AVSSGRSHFL AMDTDNNIYS 120
  121 WDSTESDQGV KIEFANLPSR ATNPILKIAS GWNFNCCYIY KVGLVAWKER DAIQKGESFA 180
  181 FAKYEIVPNT NDVNGDSRIV DFACLQDNCV FFINNNGDKL WKYHNGLNQI VDLNIVGKLC 240
  241 KINACFASLV LFTDTHCYTL KVTNGDVDKD SLTELDINEN VISVASGDYH TVALTERGHL 300
  301 YSWGIESQDC GCLGLGPSEK IVNELHIGNW EGQRNIRVVK PTKIELPEDY ICVSVTAGGW 360
  361 QTGALIIKKH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.69897
Match: 1a12A
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.074598603744 bayes_pls_golite062009
small conjugating protein ligase activity 4.98706956258248 bayes_pls_golite062009
acid-amino acid ligase activity 4.24569482624066 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.41677849112717 bayes_pls_golite062009
ligase activity 1.85186470582778 bayes_pls_golite062009
binding 0.714930161612764 bayes_pls_golite062009
catalytic activity 0.261970921089142 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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