| Protein: | THI22 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 572 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THI22.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..572] | [1..572] |
|
|
0.0 | [46..569] | [36..536] |
|
|
0.0 | [44..567] | [10..506] |
|
|
0.0 | [27..571] | [195..736] |
|
|
0.0 | [46..571] | [7..520] |
|
|
0.0 | [44..539] | [10..500] |
|
|
3.0E-97 | [44..571] | [31..587] |
|
Region A: Residues: [1-320] |
1 11 21 31 41 51
| | | | | |
1 MVIILLGLCT LGFPRTAFCP SIMTNSTVSI NTPPPYLTLA CNEKLPTVMS IAGSDSSGGA 60
61 GVEADIKTIT AHRCYAMTCV TTLTAQTPVK VYGAHNIPKK MVSQILDANL QDMKCNVIKT 120
121 GMLTVDAIEV LHEKLLQLGE NRPKLVIDPV LCAASDSSPT GKDVVSLIIE KISPFADILT 180
181 PNISDCFMLL GENREVSKLQ DVLEIAKDLS RITNCSNILV KGGHIPCDDG KEKHITDVLY 240
241 LGAEQKFITF KGQFVNTTRT HGAGCTLASA IASNLARGYS LSQSVYGGIE YVQNAIAIGC 300
301 DVTKKAVKVG PINHVYAVEI
|
| Detection Method: |  |
| Confidence: | 308.9794 |
| Match: | 1jxhA_ |
| Description: | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphomethylpyrimidine kinase activity | 3.972577109569 | bayes_pls_golite062009 |
| kinase activity | 2.74755351135221 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.43969902311075 | bayes_pls_golite062009 |
| carbohydrate kinase activity | 2.34445983129813 | bayes_pls_golite062009 |
| thiaminase activity | 2.33383885490808 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31951903725366 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 2.29466565429735 | bayes_pls_golite062009 |
| transferase activity | 2.15883296431019 | bayes_pls_golite062009 |
| nucleic acid binding | 2.14277879659132 | bayes_pls_golite062009 |
| DNA binding | 1.96007866678724 | bayes_pls_golite062009 |
| catalytic activity | 1.74474587246986 | bayes_pls_golite062009 |
| binding | 1.4216897826135 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.37866801006693 | bayes_pls_golite062009 |
| hydroxyethylthiazole kinase activity | 1.28568044601242 | bayes_pls_golite062009 |
| thiamin-phosphate diphosphorylase activity | 1.27602595951972 | bayes_pls_golite062009 |
| transcription factor activity | 1.22047633822494 | bayes_pls_golite062009 |
| phosphofructokinase activity | 0.37205329607884 | bayes_pls_golite062009 |
| pyridoxal kinase activity | 0.217863391052366 | bayes_pls_golite062009 |
| protein binding | 0.117280046908929 | bayes_pls_golite062009 |
|
Region A: Residues: [321-572] |
1 11 21 31 41 51
| | | | | |
1 PLEKMLTDEC FTASDAVPKK PIEGSLDKIP GGSFFNYLIN HPKVKPHWDA YVNHEFVKRV 60
61 ADGTLERKKF QFFIEQDYLY LIDYVRVCCV TGSKSPTLED LEKDLVIADC ARNELNEHER 120
121 RLREEFGVKD PDYLQKIKRG PALRAYCRYL IDISRRGNWQ EIVVALNPCL MGYVYAVDKV 180
181 KDKITAAEGS IYSEWCDTCA SSFCYQAVLE GERLMNHILE TYPPDQLDSL VTIFARGCEL 240
241 ETNFWTAAME YE
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 2.47421036599568 | bayes_pls_golite062009 |
| binding | 1.80342520508546 | bayes_pls_golite062009 |
| transcription activator activity | 0.765671114434415 | bayes_pls_golite062009 |
| catalytic activity | 0.476060647762462 | bayes_pls_golite062009 |
| protein binding | 0.438212622992804 | bayes_pls_golite062009 |
