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View Structure Prediction Details

Protein: SEC8
Organism: Saccharomyces cerevisiae
Length: 1065 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC8.

Description E-value Query
Range
Subject
Range
SEC8_YEAST - Exocyst complex component SEC8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC8 PE=1...
gi|190407993 - gi|190407993|gb|EDV11258.1| exocyst complex component SEC8 [Saccharomyces cerevisiae RM11-1a]
SEC8 - Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p,...
0.0 [1..1065] [1..1065]
EXOC4_MOUSE - Exocyst complex component 4 OS=Mus musculus GN=Exoc4 PE=1 SV=2
0.0 [54..1012] [24..948]
EXOC4 - exocyst complex component 4
gi|117645680 - gi|117645680|emb|CAL38306.1| hypothetical protein [synthetic construct]
0.0 [54..1012] [24..947]
EXOC4_RAT - Exocyst complex component 4 OS=Rattus norvegicus GN=Exoc4 PE=1 SV=1
0.0 [54..1012] [24..948]
SEC8_NEUCR - Probable exocyst complex component sec8 OS=Neurospora crassa GN=sec-8 PE=3 SV=1
SEC8_NEUCR - Probable exocyst complex component sec8 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 7...
0.0 [5..976] [61..1017]
sec8 - exocyst complex subunit Sec8
SEC8_SCHPO - Exocyst complex component sec8 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sec8 PE=1 S...
0.0 [4..976] [21..1025]
sec8-PA - The gene sec8 is referred to in FlyBase by the symbol Dmel\sec8 (CG2095, FBgn0086685). It is a prote...
0.0 [56..996] [28..951]

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Predicted Domain #1
Region A:
Residues: [1-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYLKPAQKG RRRGLSINSL SETQQSAMNS SLDHLQNDLN RINLQWNRIL SDNTNPLELA  60
   61 LAFLDDTSVG LGHRYEEFNQ LKSQIGSHLQ DVVNEHSQVF NTNVASYGKA VSSIMQAQEQ 120
  121 TLNLKNCLKE ANEKITTDKG SLQELNDNNL KYTKMIDVLV NIEELLQIPE KIEENIRKEN 180
  181 FHQVQILLER GFILMNNKSL KTVEILKPIN QQLELQEHLL FNNLIEEIHD IMYSKSNKTN 240
  241 FTRVTNNDIF KIISISHNGF TSLENYLYNI VNIDIMEHSK TINKNLEQFI HDQSLNKGNI 300
  301 MLQENAATQA PLAPSRNQEN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [321-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGFNRIGFLL KTINNINKLP VAFNIITERA KEEIHNIIVK STESIRSKHP SLLKMATSLK  60
   61 NDNHFGLPVQ DILSIILREC FWEIFLKLLY AIQCHRAIFE MSNILQPTSS AKPAFKFNKI 120
  121 WGKLLDEIEL LLVRYINDPE LISSNNGSIK PINGATNNAP TLPKRKNPKI FSLEYNIEDN 180
  181 SSVKDQAFEL KALLKDIFPG FSVSSNMDLD SIYVKDESFE QDEPLVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [548-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVFNMKVIL DPFLLFTQST STIVPSVLTQ NTISSLTFFD DYMNKSFLPK IQMTMDYLFT  60
   61 VEVESNNPYA LELSDENHNI FKTALDFQRL FYNLLNVFNT ANTFREKISY CILDLLNHFY 120
  121 NYYLGLFNSL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.918 N/A N/A a.24.14 FAT domain of focal adhesion kinase

Predicted Domain #4
Region A:
Residues: [678-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGTSDRHLTR KIITAWLQNG ILMDQEQKIL NGDETLFHEE SIELFKEIPH FYQAGKGLSK  60
   61 SDLFNNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [745-1013]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLDTILQFSA SVLWILNWLP GLKKAINIDE VSQEPMLDAD RLRSSWTFSE SMDLNYSNPS  60
   61 SSPNSLGNLK ILLDDKASKK FDETIDGFKT LKFKLITILR FNIRALCIYD IGSFFQNTKI 120
  121 WNMDVGSIEL DQNIASLISE LRRTESKLKQ QLPEKEKNSI FIGLDIVNNY ALIKGAKSIK 180
  181 VLNHNGIKKM LRNVNVLQHA YRNLSSEPSK INMNVTMNFY SLCGSSEAEL FEYIKDNELP 240
  241 HCSVEDLKTI LRLQFSEEMH RQLKRQSTS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1014-1065]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STKGSIKPSN KRYTEALEKL SNLEKEQSKE GARTKIGKLK SKLNAVHTAN EK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle