| Protein: | SEC8 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1065 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC8.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1065] | [1..1065] |
|
|
0.0 | [54..1012] | [24..948] |
|
|
0.0 | [54..1012] | [24..947] |
|
|
0.0 | [54..1012] | [24..948] |
|
|
0.0 | [5..976] | [61..1017] |
|
|
0.0 | [4..976] | [21..1025] |
|
|
0.0 | [56..996] | [28..951] |
|
Region A: Residues: [1-320] |
1 11 21 31 41 51
| | | | | |
1 MDYLKPAQKG RRRGLSINSL SETQQSAMNS SLDHLQNDLN RINLQWNRIL SDNTNPLELA 60
61 LAFLDDTSVG LGHRYEEFNQ LKSQIGSHLQ DVVNEHSQVF NTNVASYGKA VSSIMQAQEQ 120
121 TLNLKNCLKE ANEKITTDKG SLQELNDNNL KYTKMIDVLV NIEELLQIPE KIEENIRKEN 180
181 FHQVQILLER GFILMNNKSL KTVEILKPIN QQLELQEHLL FNNLIEEIHD IMYSKSNKTN 240
241 FTRVTNNDIF KIISISHNGF TSLENYLYNI VNIDIMEHSK TINKNLEQFI HDQSLNKGNI 300
301 MLQENAATQA PLAPSRNQEN
|
| Detection Method: |  |
| Confidence: | 12.69897 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [321-547] |
1 11 21 31 41 51
| | | | | |
1 EGFNRIGFLL KTINNINKLP VAFNIITERA KEEIHNIIVK STESIRSKHP SLLKMATSLK 60
61 NDNHFGLPVQ DILSIILREC FWEIFLKLLY AIQCHRAIFE MSNILQPTSS AKPAFKFNKI 120
121 WGKLLDEIEL LLVRYINDPE LISSNNGSIK PINGATNNAP TLPKRKNPKI FSLEYNIEDN 180
181 SSVKDQAFEL KALLKDIFPG FSVSSNMDLD SIYVKDESFE QDEPLVP
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [548-677] |
1 11 21 31 41 51
| | | | | |
1 PSVFNMKVIL DPFLLFTQST STIVPSVLTQ NTISSLTFFD DYMNKSFLPK IQMTMDYLFT 60
61 VEVESNNPYA LELSDENHNI FKTALDFQRL FYNLLNVFNT ANTFREKISY CILDLLNHFY 120
121 NYYLGLFNSL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.918 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.783 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.756 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.731 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.682 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.622 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.609 | N/A | N/A | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.597 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.577 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.575 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.570 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.569 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.548 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.546 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.521 | N/A | N/A | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.483 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.483 | N/A | N/A | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.477 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.443 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.423 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.413 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.406 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.401 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.390 | N/A | N/A | a.24.11 | Bacterial GAP domain |
| View | Download | 0.378 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.378 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.378 | N/A | N/A | a.48.2 | Transferrin receptor ectodomain, C-terminal domain |
| View | Download | 0.372 | N/A | N/A | c.92.2 | "Helical backbone" metal receptor |
| View | Download | 0.372 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.358 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.353 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.345 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.343 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.342 | N/A | N/A | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.339 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.333 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.328 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.326 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.323 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.321 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.317 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.309 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.309 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.306 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.301 | N/A | N/A | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.298 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.297 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.293 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.278 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.278 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.272 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.271 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.271 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.270 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.269 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.265 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.257 | N/A | N/A | c.14.1 | ClpP/crotonase |
| View | Download | 0.257 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.253 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.251 | N/A | N/A | a.123.1 | Nuclear receptor ligand-binding domain |
| View | Download | 0.245 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.238 | N/A | N/A | f.1.2 | Diphtheria toxin, middle domain |
| View | Download | 0.235 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.234 | N/A | N/A | a.87.1 | DBL homology domain (DH-domain) |
| View | Download | 0.232 | N/A | N/A | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.230 | N/A | N/A | a.19.1 | Fertilization protein |
| View | Download | 0.229 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.227 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.226 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.225 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.225 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.220 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.218 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.214 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.211 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.210 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.207 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
|
Region A: Residues: [678-744] |
1 11 21 31 41 51
| | | | | |
1 IGTSDRHLTR KIITAWLQNG ILMDQEQKIL NGDETLFHEE SIELFKEIPH FYQAGKGLSK 60
61 SDLFNNL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.685 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.664 | a.77.1 | DEATH domain |
| View | Download | 0.593 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.548 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.483 | d.58.49 | YajQ-like |
| View | Download | 0.443 | a.77.1 | DEATH domain |
| View | Download | 0.437 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.433 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.431 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) |
| View | Download | 0.416 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.413 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.407 | a.77.1 | DEATH domain |
| View | Download | 0.382 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.369 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.357 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.346 | d.68.3 | SirA-like |
| View | Download | 0.343 | a.4.1 | Homeodomain-like |
| View | Download | 0.328 | d.6.1 | Prion-like |
| View | Download | 0.321 | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.320 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.320 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.310 | a.3.1 | Cytochrome c |
| View | Download | 0.307 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.284 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.282 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.277 | a.3.1 | Cytochrome c |
| View | Download | 0.276 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.274 | a.4.1 | Homeodomain-like |
| View | Download | 0.274 | d.42.1 | POZ domain |
| View | Download | 0.272 | a.77.1 | DEATH domain |
| View | Download | 0.272 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.266 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.254 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.253 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.248 | d.48.1 | RecA protein, C-terminal domain |
| View | Download | 0.247 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.246 | a.3.1 | Cytochrome c |
| View | Download | 0.245 | a.3.1 | Cytochrome c |
| View | Download | 0.244 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.240 | a.4.1 | Homeodomain-like |
| View | Download | 0.232 | a.64.1 | Saposin |
| View | Download | 0.226 | a.140.1 | LEM domain |
| View | Download | 0.222 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.222 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.221 | a.65.1 | Annexin |
| View | Download | 0.217 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.216 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.210 | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.208 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.206 | a.83.1 | Guanido kinase N-terminal domain |
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Region A: Residues: [745-1013] |
1 11 21 31 41 51
| | | | | |
1 TLDTILQFSA SVLWILNWLP GLKKAINIDE VSQEPMLDAD RLRSSWTFSE SMDLNYSNPS 60
61 SSPNSLGNLK ILLDDKASKK FDETIDGFKT LKFKLITILR FNIRALCIYD IGSFFQNTKI 120
121 WNMDVGSIEL DQNIASLISE LRRTESKLKQ QLPEKEKNSI FIGLDIVNNY ALIKGAKSIK 180
181 VLNHNGIKKM LRNVNVLQHA YRNLSSEPSK INMNVTMNFY SLCGSSEAEL FEYIKDNELP 240
241 HCSVEDLKTI LRLQFSEEMH RQLKRQSTS
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1014-1065] |
1 11 21 31 41 51
| | | | | |
1 STKGSIKPSN KRYTEALEKL SNLEKEQSKE GARTKIGKLK SKLNAVHTAN EK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.733 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.674 | g.2.2 | Neurotoxin B-IV |
| View | Download | 0.599 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.481 | a.30.1 | ROP protein |
| View | Download | 0.398 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.397 | a.2.7 | tRNA-binding arm |
| View | Download | 0.384 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.363 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.346 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.324 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.318 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.307 | a.126.1 | Serum albumin-like |
| View | Download | 0.296 | a.4.1 | Homeodomain-like |
| View | Download | 0.293 | d.58.17 | Metal-binding domain |
| View | Download | 0.283 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.277 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.271 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.268 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.258 | a.2.3 | Chaperone J-domain |
| View | Download | 0.257 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.254 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.254 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.253 | a.2.7 | tRNA-binding arm |
| View | Download | 0.250 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.237 | a.112.1 | Description not found. |
| View | Download | 0.236 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.229 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.225 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.225 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.217 | f.30.1 | Photosystem I reaction center subunit X, PsaK |
| View | Download | 0.216 | a.31.1 | Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit |
| View | Download | 0.211 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
