| Protein: | PUF2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1075 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUF2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1075] | [1..1075] |
|
|
0.0 | [24..867] | [101..948] |
|
|
0.0 | [64..867] | [252..1031] |
|
Region A: Residues: [1-279] |
1 11 21 31 41 51
| | | | | |
1 MDNKRLYNGN LSNIPEVIDP GITIPIYEED IRNDTRMNTN ARSVRVSDKR GRSSSTSPQK 60
61 IGSYRTRAGR FSDTLTNLLP SISAKLHHSK KSTPVVVVPP TSSTPDSLNS TTYAPRVSSD 120
121 SFTVATPLSL QSTTTRTRTR NNTVSSQITA SSSLTTDVGN ATSANIWSAN AESNTSSSPL 180
181 FDYPLATSYF EPLTRFKSTD NYTLPQTAQL NSFLEKNGNP NIWSSAGNSN TDHLNTPIVN 240
241 RQRSQSQSTT NRVYTDAPYY QQPAQNYQVQ VPPRVPKST
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [280-454] |
1 11 21 31 41 51
| | | | | |
1 SISPVILDDV DPASINWITA NQKVPLVNQI SALLPTNTIS ISNVFPLQPT QQHQQNAVNL 60
61 TSTSLATLCS QYGKVLSART LRGLNMALVE FSTVESAICA LEALQGKELS KVGAPSTVSF 120
121 ARVLPMYEQP LNVNGFNNTP KQPLLQEQLN HGVLNYQLQQ SLQQPELQQQ PTSFN
|
| Detection Method: | |
| Confidence: | 3.040959 |
| Match: | PF00076 |
| Description: | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [455-511] |
1 11 21 31 41 51
| | | | | |
1 QPNLTYCNPT QNLSHLQLSS NENEPYPFPL PPPSLSDSKK DILHTISSFK LEYDHLE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.539 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.414 | b.40.6 | MOP-like |
| View | Download | 0.414 | c.55.4 | Translational machinery components |
| View | Download | 0.587 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.414 | d.68.7 | R3H domain |
| View | Download | 0.383 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.324 | d.10.1 | DNA-binding domain |
| View | Download | 0.312 | d.93.1 | SH2 domain |
| View | Download | 0.309 | d.58.17 | Metal-binding domain |
| View | Download | 0.289 | d.93.1 | SH2 domain |
| View | Download | 0.281 | d.58.17 | Metal-binding domain |
| View | Download | 0.273 | d.10.1 | DNA-binding domain |
| View | Download | 0.270 | d.93.1 | SH2 domain |
| View | Download | 0.247 | b.40.6 | MOP-like |
| View | Download | 0.246 | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.241 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.228 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.228 | d.58.17 | Metal-binding domain |
| View | Download | 0.228 | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.218 | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.217 | d.68.4 | YhbY-like |
| View | Download | 0.208 | c.10.2 | L domain-like |
|
Region A: Residues: [512-650] |
1 11 21 31 41 51
| | | | | |
1 LNHLLQNALK NKGVSDTNYF GPLPEHNSKV PKRKDTFDAP KLRELRKQFD SNSLSTIEME 60
61 QLAIVMLDQL PELSSDYLGN TVIQKLFENS SNIIRDIMLR KCNKYLTSMG VHKNGTWVCQ 120
121 KIIKMANTPR QINLVTSGV
|
| Detection Method: | |
| Confidence: | 200.0103 |
| Match: | 1ib2A_ |
| Description: | Pumilio 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| RNA binding | 4.2310970544603 | bayes_pls_golite062009 |
| mRNA binding | 3.1237691117539 | bayes_pls_golite062009 |
| nucleic acid binding | 2.87272982027282 | bayes_pls_golite062009 |
| binding | 2.24760917108348 | bayes_pls_golite062009 |
| 1.12277203340218 | bayes_pls_golite062009 | |
| single-stranded RNA binding | 1.08300488237934 | bayes_pls_golite062009 |
| protein binding | 0.361619805766015 | bayes_pls_golite062009 |
| hydrolase activity | 0.181856784298799 | bayes_pls_golite062009 |
| poly-pyrimidine tract binding | 0.137774615811754 | bayes_pls_golite062009 |
| transcription regulator activity | 0.0600612010525731 | bayes_pls_golite062009 |
| DNA binding | 0.0239003246213715 | bayes_pls_golite062009 |
| mRNA 3'-UTR binding | 0.00441912341140061 | bayes_pls_golite062009 |
|
Region A: Residues: [651-751] |
1 11 21 31 41 51
| | | | | |
1 SDYCTPLFND QFGNYVIQGI LKFGFPWNSF IFESVLSHFW TIVQNRYGSR AVRACLEADS 60
61 IITQCQLLTI TSLIIVLSPY LATDTNGTLL ITWLLDTCTL P
|
| Detection Method: | |
| Confidence: | 200.0103 |
| Match: | 1ib2A_ |
| Description: | Pumilio 1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [752-899] |
1 11 21 31 41 51
| | | | | |
1 NKNLILCDKL VNKNLVKLCC HKLGSLTVLK ILNLRGGEEE ALSKNKIIHA IFDGPISSDS 60
61 ILFQILDEGN YGPTFIYKVL TSRILDNSVR DEAITKIRQL ILNSNINLQS RQLLEEVGLS 120
121 SAGISPKQSS KNHRKQHPQG FHSPGRAR
|
| Detection Method: | |
| Confidence: | 200.0103 |
| Match: | 1ib2A_ |
| Description: | Pumilio 1 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| RNA binding | 2.11573661150436 | bayes_pls_golite062009 |
| binding | 1.83406697369076 | bayes_pls_golite062009 |
| protein binding | 1.04044934052933 | bayes_pls_golite062009 |
| nucleic acid binding | 0.967597910409065 | bayes_pls_golite062009 |
| mRNA binding | 0.73831124805124 | bayes_pls_golite062009 |
| hydrolase activity | 0.0579816100130538 | bayes_pls_golite062009 |
| transcription regulator activity | 0.022274123463527 | bayes_pls_golite062009 |
|
Region A: Residues: [900-1075] |
1 11 21 31 41 51
| | | | | |
1 GVSVSSVRSS NSRHNSVIQM NNAGPTPALN FNPAPMSEIN SYFNNQQVVY SGNQNQNQNG 60
61 NSNGLDELNS QFDSFRIANG TNLSLPIVNL PNVSNNNNNY NNSGYSSQMN PLSRSVSHNN 120
121 NNNTNNYNNN DNDNNNNNNN NNNNNNNNNN NNNNSNNSNN NNNNDTSLYR YRSYGY
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
