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Protein Overview: PUF2_YEAST

General Information:
Name(s) found: PUF2_YEAST [Swiss-Prot]
Description(s) found:
  • mRNA-binding protein PUF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUF2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1075 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNKRLYNGN LSNIPEVIDP GITIPIYEED IRNDTRMNTN ARSVRVSDKR GRSSSTSPQK  60
   61 IGSYRTRAGR FSDTLTNLLP SISAKLHHSK KSTPVVVVPP TSSTPDSLNS TTYAPRVSSD 120
  121 SFTVATPLSL QSTTTRTRTR NNTVSSQITA SSSLTTDVGN ATSANIWSAN AESNTSSSPL 180
  181 FDYPLATSYF EPLTRFKSTD NYTLPQTAQL NSFLEKNGNP NIWSSAGNSN TDHLNTPIVN 240
  241 RQRSQSQSTT NRVYTDAPYY QQPAQNYQVQ VPPRVPKSTS ISPVILDDVD PASINWITAN 300
  301 QKVPLVNQIS ALLPTNTISI SNVFPLQPTQ QHQQNAVNLT STSLATLCSQ YGKVLSARTL 360
  361 RGLNMALVEF STVESAICAL EALQGKELSK VGAPSTVSFA RVLPMYEQPL NVNGFNNTPK 420
  421 QPLLQEQLNH GVLNYQLQQS LQQPELQQQP TSFNQPNLTY CNPTQNLSHL QLSSNENEPY 480
  481 PFPLPPPSLS DSKKDILHTI SSFKLEYDHL ELNHLLQNAL KNKGVSDTNY FGPLPEHNSK 540
  541 VPKRKDTFDA PKLRELRKQF DSNSLSTIEM EQLAIVMLDQ LPELSSDYLG NTVIQKLFEN 600
  601 SSNIIRDIML RKCNKYLTSM GVHKNGTWVC QKIIKMANTP RQINLVTSGV SDYCTPLFND 660
  661 QFGNYVIQGI LKFGFPWNSF IFESVLSHFW TIVQNRYGSR AVRACLEADS IITQCQLLTI 720
  721 TSLIIVLSPY LATDTNGTLL ITWLLDTCTL PNKNLILCDK LVNKNLVKLC CHKLGSLTVL 780
  781 KILNLRGGEE EALSKNKIIH AIFDGPISSD SILFQILDEG NYGPTFIYKV LTSRILDNSV 840
  841 RDEAITKIRQ LILNSNINLQ SRQLLEEVGL SSAGISPKQS SKNHRKQHPQ GFHSPGRARG 900
  901 VSVSSVRSSN SRHNSVIQMN NAGPTPALNF NPAPMSEINS YFNNQQVVYS GNQNQNQNGN 960
  961 SNGLDELNSQ FDSFRIANGT NLSLPIVNLP NVSNNNNNYN NSGYSSQMNP LSRSVSHNNN1020
 1021 NNTNNYNNND NDNNNNNNNN NNNNNNNNNN NNNSNNSNNN NNNDTSLYRY RSYGY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..279] MSA 15.438997 View MSA. No confident structure predictions are available.
    2 View Details [280..454] Pfam 3.040959 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) No confident structure predictions are available.
    3 View Details [455..511] deduced N/A No confident structure predictions are available.
    4 View Details [512..650] PSI-BLAST 200.0103 Pumilio 1
    5 View Details [651..751] PSI-BLAST 200.0103 Pumilio 1
    6 View Details [752..899] PSI-BLAST 200.0103 Pumilio 1
    7 View Details [900..1075] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  4.2310970544603 bayes_pls_golite062009
  • mRNA binding
    		•  3.1237691117539 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.87272982027282 bayes_pls_golite062009
  • binding
    		•  2.24760917108348 bayes_pls_golite062009
    		• 1.12277203340218 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.08300488237934 bayes_pls_golite062009
  • protein binding
    		•  0.361619805766015 bayes_pls_golite062009
  • hydrolase activity
    		•  0.181856784298799 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.137774615811754 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0600612010525731 bayes_pls_golite062009
  • DNA binding
    		•  0.0239003246213715 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.00441912341140061 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • RNA binding
    		•  2.11573661150436 bayes_pls_golite062009
  • binding
    		•  1.83406697369076 bayes_pls_golite062009
  • protein binding
    		•  1.04044934052933 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.967597910409065 bayes_pls_golite062009
  • mRNA binding
    		•  0.73831124805124 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0579816100130538 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.022274123463527 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle