| Protein: | THI21 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 551 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THI21.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..551] | [23..572] |
|
|
0.0 | [3..548] | [14..536] |
|
|
0.0 | [24..550] | [7..520] |
|
|
0.0 | [21..546] | [9..506] |
|
|
0.0 | [8..550] | [198..736] |
|
|
0.0 | [21..518] | [9..500] |
|
|
4.0E-99 | [12..550] | [21..587] |
|
Region A: Residues: [1-319] |
1 11 21 31 41 51
| | | | | |
1 MTYSTVNINT PPPYLALASN EKLPTVLSIA GTDPSGGAGV EADVKTITAH RCYAMTCITA 60
61 LNAQTPVKVY SINNTPKEVV SQILDANLQD MKCDVIKTGM LTTAAIEVLH EKLLQLGENR 120
121 PKLVVDPVLV ATSGSSLAGK DIASLITEKI APFADILTPN IPECFKLLGE DREISKLRDI 180
181 FEVAKDLAKI TKCSNILVKG GHIPWNDEEG KYITDVLYLG AEQRFITFKG NFVNTTHTHG 240
241 TGCTLASAIA SNLARGYSLP QSVYGGIEYV QNAVAIGCDV TKETVKDNGP INHVYAIEIP 300
301 LEKMLSDECF TASDAVHKK
|
| Detection Method: |  |
| Confidence: | 364.512579 |
| Match: | 1jxhA_ |
| Description: | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphomethylpyrimidine kinase activity | 3.972577109569 | bayes_pls_golite062009 |
| kinase activity | 2.74755351135221 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.43969902311075 | bayes_pls_golite062009 |
| carbohydrate kinase activity | 2.34445983129813 | bayes_pls_golite062009 |
| thiaminase activity | 2.33383885490808 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31951903725366 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 2.29466565429735 | bayes_pls_golite062009 |
| transferase activity | 2.15883296431019 | bayes_pls_golite062009 |
| nucleic acid binding | 2.14277879659132 | bayes_pls_golite062009 |
| DNA binding | 1.96007866678724 | bayes_pls_golite062009 |
| catalytic activity | 1.74474587246986 | bayes_pls_golite062009 |
| binding | 1.4216897826135 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.37866801006693 | bayes_pls_golite062009 |
| hydroxyethylthiazole kinase activity | 1.28568044601242 | bayes_pls_golite062009 |
| thiamin-phosphate diphosphorylase activity | 1.27602595951972 | bayes_pls_golite062009 |
| transcription factor activity | 1.22047633822494 | bayes_pls_golite062009 |
| phosphofructokinase activity | 0.37205329607884 | bayes_pls_golite062009 |
| pyridoxal kinase activity | 0.217863391052366 | bayes_pls_golite062009 |
| protein binding | 0.117280046908929 | bayes_pls_golite062009 |
|
Region A: Residues: [320-551] |
1 11 21 31 41 51
| | | | | |
1 PVKSSLNKIP GGSFYKYLIN HPKVKPHWDS YVNHDFVRKV ADGSLEPKKF QFFIEQDYLY 60
61 LVNYARISCI AGSKSPCLED LEKELVIVEC VRNGLCQHER RLREEFGIKD PDYLQKIQRG 120
121 PALRAYCRYF NDVSRRGNWQ ELVIALNPCL MGYVHALTKI KDEVTAAEGS VYREWCETYS 180
181 SSWCHEAMLE GEKLLNHILE TYPPEKLDTL VTIYAEVCEL EANFWTAALE YE
|
| Detection Method: | |
| Confidence: | 98.481486 |
| Match: | PF03070 |
| Description: | TENA/THI-4/PQQC family |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 2.47421036599568 | bayes_pls_golite062009 |
| binding | 1.80342520508546 | bayes_pls_golite062009 |
| transcription activator activity | 0.765671114434415 | bayes_pls_golite062009 |
| catalytic activity | 0.476060647762462 | bayes_pls_golite062009 |
| protein binding | 0.438212622992804 | bayes_pls_golite062009 |
