| Protein: | BEM3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1128 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BEM3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1128] | [1..1128] |
|
|
0.0 | [12..1128] | [16..1013] |
|
|
0.0 | [23..1110] | [44..1249] |
|
|
0.0 | [55..1111] | [228..1312] |
|
|
0.0 | [265..1128] | [1069..1853] |
|
|
0.0 | [265..1128] | [1070..1855] |
|
|
0.0 | [570..1113] | [54..597] |
|
|
0.0 | [563..1108] | [5..546] |
|
Region A: Residues: [1-155] |
1 11 21 31 41 51
| | | | | |
1 MTDNLTTTHG GSTTLELLAQ YNDHRSKKDK SIEHIEKGTC SGKERNPSYD EIFTENIKLK 60
61 LQVQEYETEI ESLEKVIDML QKNREASLEV VLEQVQNDSR DSYVNDQSFV LPPRSAERKA 120
121 HIKSLNLPIP TLSPPLQQGS DVALETSVTP TVPQI
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [156-511] |
1 11 21 31 41 51
| | | | | |
1 GVTSNTSISR KHLQNMILND EIEANSSFSS PKIINRSVSS PTKIHSEQLA SPAASVTYTT 60
61 SRITIKSPNK GSKSPLQERL RSPQNPNRMT AVINNHLHSP LKASTSNNLD ELTESKSQQL 120
121 TNDAIQKNDR VYSSITSSAY TTGTPTSAAK SPSSLLEVKE GENKALGFSP ASKEKLDDFT 180
181 QLLDSSFGEE DLVNTDSKDP LSIKSTINES LPPPPAPPTF FSPTSSGNIK NSTPLSSHLA 240
241 SPVILNKKDD NFGAQSAKNL KKPVLTSSLP NLSTKLSTTS QNASLPPNPP VESSSKQKQL 300
301 GETASIHSTN TLNTFSSTPQ GSLKTLRRPH ASSVSTVKSV AQSLKSDIPL FVQPED
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [512-629] |
1 11 21 31 41 51
| | | | | |
1 FGTIQIEVLS TLYRDNEDDL SILIAIIDRK SGKEMFKFSK SIHKVRELDV YMKSHVPDLP 60
61 LPTLPDRQLF QTLSPTKVDT RKNILNQYYT SIFSVPEFPK NVGLKIAQFI STDTVMTP
|
| Detection Method: | |
| Confidence: | 11.309804 |
| Match: | PF00787 |
| Description: | PX domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [630-748] |
1 11 21 31 41 51
| | | | | |
1 PMMDDNVKDG SLLLRRPKTL TGNSTWRVRY GILRDDVLQL FDKNQLTETI KLRQSSIELI 60
61 PNLPEDRFGT RNGFLITEHK KSGLSTSTKY YICTETSKER ELWLSAFSDY IDPSQSLSL
|
| Detection Method: | |
| Confidence: | 13.79588 |
| Match: | PF00169 |
| Description: | PH domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.28961137539184 | bayes_pls_golite062009 |
| protein binding | 1.67421332231525 | bayes_pls_golite062009 |
|
Region A: Residues: [749-872] |
1 11 21 31 41 51
| | | | | |
1 SSSRNANDTD SASHLSAGTH HSKFGNATIS ATDTPSYVTD LTQEYNNNNN ISNSSNNIAN 60
61 SDGIDSNPSS HSNFLASSSG NAEEEKDSRR AKMRSLFPFK KLTGPASAMN HIGITISNDS 120
121 DSPT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.52256824388179 | bayes_pls_golite062009 |
| protein binding | 1.95763087285706 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.50594272418871 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.48917924547615 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.16730573804866 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.13267118951633 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.10613306581585 | bayes_pls_golite062009 |
| signal transducer activity | 0.912168757889531 | bayes_pls_golite062009 |
| molecular transducer activity | 0.912168757889531 | bayes_pls_golite062009 |
| actin binding | 0.901424255569633 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.578612934164552 | bayes_pls_golite062009 |
| small GTPase binding | 0.268376608418386 | bayes_pls_golite062009 |
| GTPase binding | 0.241736916131941 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.138736794703043 | bayes_pls_golite062009 |
|
Region A: Residues: [873-1009] |
1 11 21 31 41 51
| | | | | |
1 SPDSIIKSPS KKLMEVSSSS NSSTGPHVST AIFGSSLETC LRLSSHKYQN VYDLPSVVYR 60
61 CLEYLYKNRG IQEEGIFRLS GSSTVIKTLQ ERFDKEYDVD LCRYNESIEA KDDEASPSLY 120
121 IGVNTVSGLL KLYLRKL
|
| Detection Method: | |
| Confidence: | 108.383689 |
| Match: | 1am4A_ |
| Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1010-1128] |
1 11 21 31 41 51
| | | | | |
1 PHLLFGDEQF LSFKRVVDEN HNNPVQISLG FKELIESGLV PHANLSLMYA LFELLVRINE 60
61 NSKFNKMNLR NLCIVFSPTL NIPISMLQPF ITDFACIFQG GEPVKEEERE KVDIHIPQV
|
| Detection Method: | |
| Confidence: | 108.383689 |
| Match: | 1am4A_ |
| Description: | p50 RhoGAP domain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 5.23789256375467 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 5.21562004568462 | bayes_pls_golite062009 |
| small GTPase regulator activity | 4.91645234075732 | bayes_pls_golite062009 |
| GTPase activator activity | 4.81440293338491 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 4.76400460221691 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| enzyme regulator activity | 4.5322075775333 | bayes_pls_golite062009 |
| enzyme activator activity | 4.29367232260052 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 3.29568423512865 | bayes_pls_golite062009 |
| binding | 1.62780792681766 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.23364137263268 | bayes_pls_golite062009 |
| protein binding | 1.21496582666968 | bayes_pls_golite062009 |
| molecular transducer activity | 0.821491422669847 | bayes_pls_golite062009 |
| signal transducer activity | 0.821491422669847 | bayes_pls_golite062009 |
| actin binding | 0.47049194149211 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.269263349894465 | bayes_pls_golite062009 |
| GTPase binding | 0.240141218420366 | bayes_pls_golite062009 |
| small GTPase binding | 0.0713778754122761 | bayes_pls_golite062009 |
| kinase activity | 0.0527660937670589 | bayes_pls_golite062009 |
