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Protein Overview: BEM3_YEAST

General Information:
Name(s) found: BEM3_YEAST [Swiss-Prot]
Description(s) found:
  • GTPase-activating protein BEM3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BEM3 PE=1 SV=3 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1128 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDNLTTTHG GSTTLELLAQ YNDHRSKKDK SIEHIEKGTC SGKERNPSYD EIFTENIKLK  60
   61 LQVQEYETEI ESLEKVIDML QKNREASLEV VLEQVQNDSR DSYVNDQSFV LPPRSAERKA 120
  121 HIKSLNLPIP TLSPPLQQGS DVALETSVTP TVPQIGVTSN TSISRKHLQN MILNDEIEAN 180
  181 SSFSSPKIIN RSVSSPTKIH SEQLASPAAS VTYTTSRITI KSPNKGSKSP LQERLRSPQN 240
  241 PNRMTAVINN HLHSPLKAST SNNLDELTES KSQQLTNDAI QKNDRVYSSI TSSAYTTGTP 300
  301 TSAAKSPSSL LEVKEGENKA LGFSPASKEK LDDFTQLLDS SFGEEDLVNT DSKDPLSIKS 360
  361 TINESLPPPP APPTFFSPTS SGNIKNSTPL SSHLASPVIL NKKDDNFGAQ SAKNLKKPVL 420
  421 TSSLPNLSTK LSTTSQNASL PPNPPVESSS KQKQLGETAS IHSTNTLNTF SSTPQGSLKT 480
  481 LRRPHASSVS TVKSVAQSLK SDIPLFVQPE DFGTIQIEVL STLYRDNEDD LSILIAIIDR 540
  541 KSGKEMFKFS KSIHKVRELD VYMKSHVPDL PLPTLPDRQL FQTLSPTKVD TRKNILNQYY 600
  601 TSIFSVPEFP KNVGLKIAQF ISTDTVMTPP MMDDNVKDGS LLLRRPKTLT GNSTWRVRYG 660
  661 ILRDDVLQLF DKNQLTETIK LRQSSIELIP NLPEDRFGTR NGFLITEHKK SGLSTSTKYY 720
  721 ICTETSKERE LWLSAFSDYI DPSQSLSLSS SRNANDTDSA SHLSAGTHHS KFGNATISAT 780
  781 DTPSYVTDLT QEYNNNNNIS NSSNNIANSD GIDSNPSSHS NFLASSSGNA EEEKDSRRAK 840
  841 MRSLFPFKKL TGPASAMNHI GITISNDSDS PTSPDSIIKS PSKKLMEVSS SSNSSTGPHV 900
  901 STAIFGSSLE TCLRLSSHKY QNVYDLPSVV YRCLEYLYKN RGIQEEGIFR LSGSSTVIKT 960
  961 LQERFDKEYD VDLCRYNESI EAKDDEASPS LYIGVNTVSG LLKLYLRKLP HLLFGDEQFL1020
 1021 SFKRVVDENH NNPVQISLGF KELIESGLVP HANLSLMYAL FELLVRINEN SKFNKMNLRN1080
 1081 LCIVFSPTLN IPISMLQPFI TDFACIFQGG EPVKEEEREK VDIHIPQV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] deduced N/A No confident structure predictions are available.
    2 View Details [156..511] MSA 3.030996 View MSA. No confident structure predictions are available.
    3 View Details [512..629] Pfam 11.309804 PX domain No confident structure predictions are available.
    4 View Details [630..748] Pfam 13.79588 PH domain No confident structure predictions are available.
    5 View Details [749..872] deduced N/A No confident structure predictions are available.
    6 View Details [873..1009] PSI-BLAST 108.383689 p50 RhoGAP domain
    7 View Details [1010..1128] PSI-BLAST 108.383689 p50 RhoGAP domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.28961137539184 bayes_pls_golite062009
  • protein binding
    		•  1.67421332231525 bayes_pls_golite062009
    5
    Term Confidence Notes
  • binding
    		•  2.52256824388179 bayes_pls_golite062009
  • protein binding
    		•  1.95763087285706 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.50594272418871 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.48917924547615 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.16730573804866 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.13267118951633 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.10613306581585 bayes_pls_golite062009
  • signal transducer activity
    		•  0.912168757889531 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.912168757889531 bayes_pls_golite062009
  • actin binding
    		•  0.901424255569633 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.578612934164552 bayes_pls_golite062009
  • small GTPase binding
    		•  0.268376608418386 bayes_pls_golite062009
  • GTPase binding
    		•  0.241736916131941 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.138736794703043 bayes_pls_golite062009
    6 No functions predicted.
    7
    Term Confidence Notes
  • GTPase regulator activity
    		•  5.23789256375467 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  5.21562004568462 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  4.91645234075732 bayes_pls_golite062009
  • GTPase activator activity
    		•  4.81440293338491 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  4.76400460221691 bayes_pls_golite062009
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • enzyme regulator activity
    		•  4.5322075775333 bayes_pls_golite062009
  • enzyme activator activity
    		•  4.29367232260052 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  3.29568423512865 bayes_pls_golite062009
  • binding
    		•  1.62780792681766 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.23364137263268 bayes_pls_golite062009
  • protein binding
    		•  1.21496582666968 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.821491422669847 bayes_pls_golite062009
  • signal transducer activity
    		•  0.821491422669847 bayes_pls_golite062009
  • actin binding
    		•  0.47049194149211 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.269263349894465 bayes_pls_golite062009
  • GTPase binding
    		•  0.240141218420366 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0713778754122761 bayes_pls_golite062009
  • kinase activity
    		•  0.0527660937670589 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle