| Protein: | PIP2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 996 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIP2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..996] | [1..996] |
|
|
7.0E-77 | [3..667] | [51..629] |
|
|
5.0E-74 | [6..665] | [21..581] |
|
|
3.0E-67 | [7..663] | [35..582] |
|
Region A: Residues: [1-111] |
1 11 21 31 41 51
| | | | | |
1 MYFTDESSPA MNRVGKKRNR LSFVCQACRK AKTKCDQEKP RCGRCTKQNL FCIYDVARQA 60
61 APRNPNKDAT IARLKKEIRY WRNKTVDLTQ EKKDFYTALK RPTEELAARR T
|
| Detection Method: |  |
| Confidence: | 59.68867 |
| Match: | 1hwtD_ |
| Description: | Hap1 (Cyp1); HAP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.56444258780502 | bayes_pls_golite062009 |
| DNA binding | 4.26146437716972 | bayes_pls_golite062009 |
| nucleic acid binding | 3.86871420827942 | bayes_pls_golite062009 |
| transcription factor activity | 3.049435548132 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.98081393153291 | bayes_pls_golite062009 |
| binding | 2.91929847152301 | bayes_pls_golite062009 |
| transcription activator activity | 2.24483536326713 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.03201524223606 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.86200506906385 | bayes_pls_golite062009 |
|
Region A: Residues: [112-250] |
1 11 21 31 41 51
| | | | | |
1 CKSLQENSFP ISLYKTHPRL IMTKVMKREI NPLSEKYLIF QDTFLKTLIA SVLLSCSRNS 60
61 MIPALNADIS RSRTQPCVKN NVVKMREVLL KNSKYESQRK SINEFTDRLL QRKNPEEQIA 120
121 VNKVISLLYS NRESSYLED
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.387 | a.118.8 | TPR-like |
| View | Download | 0.371 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.490 | a.79.1 | Antitermination factor NusB |
| View | Download | 0.361 | a.152.1 | Antioxidant defence protein AhpD |
| View | Download | 0.424 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.326 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.320 | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.300 | a.25.1 | Ferritin-like |
| View | Download | 0.296 | b.81.1 | Trimeric LpxA-like enzymes |
| View | Download | 0.283 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.283 | d.224.1 | SufE-like |
| View | Download | 0.271 | a.1.1 | Globin-like |
| View | Download | 0.263 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.258 | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.251 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.249 | a.95.1 | Influenza virus matrix protein M1 |
| View | Download | 0.242 | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.240 | e.20.1 | Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment |
| View | Download | 0.230 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.228 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.218 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.209 | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.209 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.207 | a.118.1 | ARM repeat |
| View | Download | 0.206 | d.224.1 | SufE-like |
| View | Download | 0.205 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
|
Region A: Residues: [251-575] |
1 11 21 31 41 51
| | | | | |
1 TCPTENDYSD LLKGYINEIE KTLPPKAIIE QYLSHFFEHI FHLIPFASKE MLEESIHTTV 60
61 QYNELGEVRL SMGTTLIRNK MENLCILLLI LRIAYISLTF IEDKIEDYSP YITKEMLEQY 120
121 PIQSEVIFLA QQILASENWC ACANENTISC LLYIWCAFVF SPTEGDFLLE QPSDVIINLV 180
181 ILIGTSIGLH RDPSDFPALN HPEASDKRLL NLRRIQWLSI ISMATLESSL KGRLLVSPLS 240
241 MIDLFIDVRD PNCVEIYKKR VKKDLTGSES DEQLLEIHEI FFHRAQLALF LSDLNNITIS 300
301 YSGSVPMDTL ETLRVKANEL LKNKF
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [576-996] |
1 11 21 31 41 51
| | | | | |
1 QLRSVDINIY DEEKTFQKLT FNSILNSISL SGQILGKLMM LRASIALMLY FETLAMERSE 60
61 CLSFFYKYFF QCCADTISLI RFFFLYFNGS YEKVLSSLVC FITTKVIQLA VPTTMFTLLV 120
121 IIMRVELAKN MLLVKCNECN ARGDISDLPE IKEKIKSLDT IKENFERLLL EVYLLASQNL 180
181 RFKYFYIFKM LTLFDVFIQR LRKGQLFSGL FVKVDKDLTT KKIATMLELT LGINLDKSDH 240
241 LIDRLKGKNL TVNFTLDQLY QIIKEFDRIK NIGVADPQNS LNPSKPNMKD NTPTIELLLN 300
301 SSVENESVPP YSSSNDPTNV GNASTYSLAH NISNQNNEEN MPPSIGSSES NRAAPNLNFM 360
361 PINNNYNNSG SNINNNDNVK LPSNFKNYYD PPMSSLDISM DVPDIFGSLD FFDYDLLFQN 420
421 D
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [664-752] |
1 11 21 31 41 51
| | | | | |
1 GSYEKVLSSL VCFITTKVIQ LAVPTTMFTL LVIIMRVELA KNMLLVKCNE CNARGDISDL 60
61 PEIKEKIKSL DTIKENFERL LLEVYLLAS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [753-996] |
1 11 21 31 41 51
| | | | | |
1 QNLRFKYFYI FKMLTLFDVF IQRLRKGQLF SGLFVKVDKD LTTKKIATML ELTLGINLDK 60
61 SDHLIDRLKG KNLTVNFTLD QLYQIIKEFD RIKNIGVADP QNSLNPSKPN MKDNTPTIEL 120
121 LLNSSVENES VPPYSSSNDP TNVGNASTYS LAHNISNQNN EENMPPSIGS SESNRAAPNL 180
181 NFMPINNNYN NSGSNINNND NVKLPSNFKN YYDPPMSSLD ISMDVPDIFG SLDFFDYDLL 240
241 FQND
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
