| Protein: | COT1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 439 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COT1.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-84 | [1..439] | [1..439] |
|
|
5.0E-57 | [5..436] | [6..442] |
|
|
4.0E-56 | [5..436] | [6..446] |
|
|
7.0E-56 | [5..393] | [86..467] |
|
|
2.0E-54 | [5..385] | [5..377] |
|
Region A: Residues: [1-439] |
1 11 21 31 41 51
| | | | | |
1 MKLGSKQVKI ISLLLLDTVF FGIEITTGYL SHSLALIADS FHMLNDIISL VVALWAVNVA 60
61 KNRNPDSTYT YGWKRAEILG ALINAVFLIA LCVSILIEAL QRIIAPPVIE NPKFVLYVGV 120
121 AGLISNTVGL FLFHDNDQEH GHGHGHSHGG IFADHEMHMP SSHTHTHAHV DGIENTTPMD 180
181 STDNISEIMP NAIVDSFMNE NTRLLTPENA SKTPSYSTSS HTIASGGNYT EHNKRKRSLN 240
241 MHGVFLHVLG DALGNIGVML SAFFIWKTDY SWKYYTDPLV SLIITGIIFS SALPLSCKAS 300
301 KILLQATPST LSGDQVEGDL LKIPGIIAIH DFHIWNLTES IFIASLHIQL DISPEQFTDL 360
361 AKIVRSKLHR YGIHSATLQP EFITREVTST ERAGDSQGDH LQNDPLSLRP KTYGTGISGS 420
421 TCLIDDAANC NTADCLEDH
|
| Detection Method: |  |
| Confidence: | 67.568636 |
| Match: | PF01545 |
| Description: | Cation efflux family |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| cation transmembrane transporter activity | 6.20443686476571 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 6.11479851651253 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 5.71521511150856 | bayes_pls_golite062009 |
| transporter activity | 3.98293753989079 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.88313530012213 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.86867537460555 | bayes_pls_golite062009 |
| cadmium ion transmembrane transporter activity | 3.15489440737786 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 2.61862894000527 | bayes_pls_golite062009 |
| transition metal ion transmembrane transporter activity | 2.19121021485065 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.14914871177232 | bayes_pls_golite062009 |
| cation channel activity | 1.78793567733454 | bayes_pls_golite062009 |
| efflux transmembrane transporter activity | 1.41612086977895 | bayes_pls_golite062009 |
| binding | 1.28505954375411 | bayes_pls_golite062009 |
| ion channel activity | 1.24140857317889 | bayes_pls_golite062009 |
| di-, tri-valent inorganic cation transmembrane transporter activity | 1.20401058605752 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 1.19443885425411 | bayes_pls_golite062009 |
| channel activity | 1.19443885425411 | bayes_pls_golite062009 |
| substrate-specific channel activity | 1.19404477926718 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.475232131680683 | bayes_pls_golite062009 |
| protein binding | 0.318355149027855 | bayes_pls_golite062009 |
| iron ion transmembrane transporter activity | 0.186398867523746 | bayes_pls_golite062009 |
|
Region A: Residues: [107-439] |
1 11 21 31 41 51
| | | | | |
1 PVIENPKFVL YVGVAGLISN TVGLFLFHDN DQEHGHGHGH SHGGIFADHE MHMPSSHTHT 60
61 HAHVDGIENT TPMDSTDNIS EIMPNAIVDS FMNENTRLLT PENASKTPSY STSSHTIASG 120
121 GNYTEHNKRK RSLNMHGVFL HVLGDALGNI GVMLSAFFIW KTDYSWKYYT DPLVSLIITG 180
181 IIFSSALPLS CKASKILLQA TPSTLSGDQV EGDLLKIPGI IAIHDFHIWN LTESIFIASL 240
241 HIQLDISPEQ FTDLAKIVRS KLHRYGIHSA TLQPEFITRE VTSTERAGDS QGDHLQNDPL 300
301 SLRPKTYGTG ISGSTCLIDD AANCNTADCL EDH
|
| Detection Method: | |
| Confidence: | 48.522879 |
| Match: | 2qfiA |
| Description: | No description for 2qfiA was found. |
| Term | Confidence | Notes |
| cation transmembrane transporter activity | 6.60087208506814 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 6.49419690808578 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.066906606566 | bayes_pls_golite062009 |
| transporter activity | 4.27173462293249 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.19993137135137 | bayes_pls_golite062009 |
| transmembrane transporter activity | 4.18558383943492 | bayes_pls_golite062009 |
| cadmium ion transmembrane transporter activity | 3.5658659940326 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 2.68106285271045 | bayes_pls_golite062009 |
| transition metal ion transmembrane transporter activity | 2.32644140472297 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.19343183150052 | bayes_pls_golite062009 |
| efflux transmembrane transporter activity | 2.11491587250012 | bayes_pls_golite062009 |
| cation channel activity | 1.89531256510168 | bayes_pls_golite062009 |
| ion channel activity | 1.33777369753101 | bayes_pls_golite062009 |
| di-, tri-valent inorganic cation transmembrane transporter activity | 1.31663166812163 | bayes_pls_golite062009 |
| substrate-specific channel activity | 1.28221434614717 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 1.27960450391272 | bayes_pls_golite062009 |
| channel activity | 1.27960450391272 | bayes_pls_golite062009 |
| binding | 1.27456652114636 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.490905558612378 | bayes_pls_golite062009 |
| iron ion transmembrane transporter activity | 0.376948884172728 | bayes_pls_golite062009 |
| protein binding | 0.311357063667067 | bayes_pls_golite062009 |
