YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PNO1
Organism: Saccharomyces cerevisiae
Length: 274 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNO1.

Description E-value Query
Range		 Subject
Range
PNO1_YEAST - Pre-rRNA-processing protein PNO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PNO1 PE...
PNO1 - Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA ...
 1.0E-49 [1..274] [1..274]
PNO1_MOUSE - RNA-binding protein PNO1 OS=Mus musculus GN=Pno1 PE=1 SV=1
 3.0E-47 [50..274] [27..248]
PNO1 - partner of NOB1 homolog (S. cerevisiae)
 1.0E-46 [32..274] [2..252]
FUBP2_CHICK - Far upstream element-binding protein 2 OS=Gallus gallus GN=KHSRP PE=1 SV=1
 8.0E-46 [1..252] [200..454]
gi|19115426 - gi|19115426|ref|NP_594514.1| hypothetical protein SPAC2C4.11c [Schizosaccharomyces pombe 972h-]
rbp28 - RNA-binding protein Rbp28
 4.0E-43 [1..273] [1..257]
FUBP2_RAT - Far upstream element-binding protein 2 OS=Rattus norvegicus GN=Khsrp PE=1 SV=1
 8.0E-42 [1..252] [138..392]

Back

Predicted Domain #1
Region A:
Residues: [1-86] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAPTALKKA TVTPVSGQDG GSSRIIGINN TESIDEDDDD DVLLDDSDNN TAKEEVEGEE  60
   61 GSRKTHESKT VVVDDQGKPR FTSASK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-181] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQGNKIKFES RKIMVPPHRM TPLRNSWTKI YPPLVEHLKL QVRMNLKTKS VELRTNPKFT  60
   61 TDPGALQKGA DFIKAFTLGF DLDDSIALLR LDDLY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1j4wA_
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.07437653952404 bayes_pls_golite062009
mRNA binding 4.07599584461947 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 3.31174833550232 bayes_pls_golite062009
1.56143840583911 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
protein binding 1.37279927568272 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
poly-pyrimidine tract binding 0.9296581376632 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
single-stranded RNA binding 0.3686746342524 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [182-274] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IETFEVKDVK TLTGDHLSRA IGRIAGKDGK TKFAIENATR TRIVLADSKI HILGGFTHIR  60
   61 MARESVVSLI LGSPPGKVYG NLRTVASRLK ERY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1j4wA_
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle