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View Structure Prediction Details

Protein: YOR022C
Organism: Saccharomyces cerevisiae
Length: 715 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOR022C.

Description E-value Query
Range
Subject
Range
YOR22_YEAST - Probable phospholipase YOR022C, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
YOR022C - Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in...
0.0 [1..715] [1..715]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [296..705] [521..989]
YDK2_SCHPO - Probable phospholipase C20G8.02, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
SPAC20G8.02 - phospholipase
0.0 [314..699] [316..757]
CG8552-PA - This gene is referred to in FlyBase by the symbol Dmel\CG8552 (CG8552, FBgn0031990). It is a protein...
0.0 [313..698] [1510..1980]
gi|12697955 - gi|12697955|dbj|BAB21796.1| KIAA1705 protein [Homo sapiens]
3.0E-64 [316..519] [1..181]
DDHD1_BOVIN - Phospholipase DDHD1 OS=Bos taurus GN=DDHD1 PE=1 SV=1
3.0E-63 [318..519] [380..558]
gi|6755304, gi|5... - gi|6755304|ref|NP_035386.1| phosphatidylinositol transfer protein, membrane-associated 2 [Mus muscul...
8.0E-62 [518..706] [700..900]

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Predicted Domain #1
Region A:
Residues: [1-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRFTHRGLP SSTRFRNIFV RLNHIYVPWF YAIDVPNSKP YLPTYQTLHS PKKFKPFSVD  60
   61 DSNRLEKASK RQERRPVLVN EDYLFKVDLS HMELSPTYWE GPTYQVRRGV WFDSSNQPLS 120
  121 SDLTSEIEGL YKQLKFDDSN DDPTTTPPAE SQDIFRLKGK YPVDKENEGE QKNGSSNKDE 180
  181 NESTFKFILF ANKQTAFLLS DLDGGKLQLA FLRSNLAQSL PINATMITRS YKYSSSATTK 240
  241 QTSTSFKAAK TPQTEVADGS N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.429945198807351 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [262-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSRSIETK LEKKVSNLFN LSDFLQLFNG NASKDQDDAQ SLEKQMETDY NNADNSQGAN  60
   61 ASSKIEDGKN SGASDRQIRS NRRDVDNLIL CVHGIGQTLG KKYEYVNFAH TVNLLRSNMK 120
  121 KIYNNSEKLQ SLNTAPDYKS NCNVQVLPIT WRHSISFQTD AKEENI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [428-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPDLPTLSQ VTVNGVLPLR KLLADGLLDI LLYVEPYYQD MILQQVTSQL NKTYRIFKEF  60
   61 NPEF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
catalytic activity 0.531942688196759 bayes_pls_golite062009
hydrolase activity 0.464324757821572 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [492-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGKVHLVGHS LGSMILFDIL SKQKKYELEF QVDNLFFIGS PIGLLKLIQR TKIGDRPEFP  60
   61 NDLERKLTVQ RPQCKDIYNV YHVCDPISYR MEPLVSKEMA HYEQTYLPHC SEAYGLTSKV 120
  121 LEFGENIWKD LPGTDENNLQ SKKTSPEKKE VKLSENLTRM LTGLNYTGRL DYAMSPSLLE 180
  181 VDFISAIKSH VSYFEEPDIA AFILKEILSK HENASEIYVK RKTG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 89.568636
Match: PF02862
Description: DDHD domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle