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View Structure Prediction Details

Protein: YOR022C
Organism: Saccharomyces cerevisiae
Length: 715 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOR022C.

Description E-value Query
Range
Subject
Range
YOR22_YEAST - Probable phospholipase YOR022C, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
YOR022C - Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in...
0.0 [1..715] [1..715]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [296..705] [521..989]
YDK2_SCHPO - Probable phospholipase C20G8.02, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
SPAC20G8.02 - phospholipase
0.0 [314..699] [316..757]
CG8552-PA - This gene is referred to in FlyBase by the symbol Dmel\CG8552 (CG8552, FBgn0031990). It is a protein...
0.0 [313..698] [1510..1980]
gi|12697955 - gi|12697955|dbj|BAB21796.1| KIAA1705 protein [Homo sapiens]
3.0E-64 [316..519] [1..181]
DDHD1_BOVIN - Phospholipase DDHD1 OS=Bos taurus GN=DDHD1 PE=1 SV=1
3.0E-63 [318..519] [380..558]
gi|6755304, gi|5... - gi|6755304|ref|NP_035386.1| phosphatidylinositol transfer protein, membrane-associated 2 [Mus muscul...
8.0E-62 [518..706] [700..900]

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Predicted Domain #1
Region A:
Residues: [1-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRFTHRGLP SSTRFRNIFV RLNHIYVPWF YAIDVPNSKP YLPTYQTLHS PKKFKPFSVD  60
   61 DSNRLEKASK RQERRPVLVN EDYLFKVDLS HMELSPTYWE GPTYQVRRGV WFDSSNQPLS 120
  121 SDLTSEIEGL YKQLKFDDSN DDPTTTPPAE SQDIFRLKGK YPVDKENEGE QKNGSSNKDE 180
  181 NESTFKFILF ANKQTAFLLS DLDGGKLQLA FLRSNLAQSL PINATMITRS YKYSSSATTK 240
  241 QTSTSFKAAK TPQTEVADGS N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.429945198807351 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [262-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSRSIETK LEKKVSNLFN LSDFLQLFNG NASKDQDDAQ SLEKQMETDY NNADNSQGAN  60
   61 ASSKIEDGKN SGASDRQIRS NRRDVDNLIL CVHGIGQTLG KKYEYVNFAH TVNLLRSNMK 120
  121 KIYNNSEKLQ SLNTAPDYKS NCNVQVLPIT WRHSISFQTD AKEENI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [428-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPDLPTLSQ VTVNGVLPLR KLLADGLLDI LLYVEPYYQD MILQQVTSQL NKTYRIFKEF  60
   61 NPEF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.668 a.77.1 DEATH domain
View Download 0.536 f.13.1 Family A G protein-coupled receptor-like
View Download 0.525 a.60.2 RuvA domain 2-like
View Download 0.534 a.30.1 ROP protein
View Download 0.713 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.500 f.13.1 Family A G protein-coupled receptor-like
View Download 0.500 f.13.1 Family A G protein-coupled receptor-like
View Download 0.499 a.64.1 Saposin
View Download 0.489 g.2.2 Neurotoxin B-IV
View Download 0.484 a.2.3 Chaperone J-domain
View Download 0.472 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.468 a.140.1 LEM domain
View Download 0.464 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.450 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.446 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.433 d.6.1 Prion-like
View Download 0.429 f.17.1 F1F0 ATP synthase subunit C
View Download 0.420 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.419 f.13.1 Family A G protein-coupled receptor-like
View Download 0.417 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.410 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.407 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.398 a.140.1 LEM domain
View Download 0.395 f.13.1 Family A G protein-coupled receptor-like
View Download 0.393 a.30.1 ROP protein
View Download 0.392 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.392 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.389 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.387 a.30.1 ROP protein
View Download 0.387 a.30.1 ROP protein
View Download 0.386 f.13.1 Family A G protein-coupled receptor-like
View Download 0.383 d.29.1 Ribosomal protein L31e
View Download 0.382 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.379 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.374 d.80.1 Tautomerase/MIF
View Download 0.373 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.359 a.4.5 "Winged helix" DNA-binding domain
View Download 0.351 a.4.11 RNA polymerase subunit RPB10
View Download 0.348 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.348 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.342 a.144.1 PABC (PABP) domain
View Download 0.340 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.340 a.156.1 S13-like H2TH domain
View Download 0.339 f.13.1 Family A G protein-coupled receptor-like
View Download 0.338 a.2.3 Chaperone J-domain
View Download 0.335 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.335 f.13.1 Family A G protein-coupled receptor-like
View Download 0.334 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.331 f.13.1 Family A G protein-coupled receptor-like
View Download 0.329 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.323 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.323 a.64.1 Saposin
View Download 0.318 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.311 f.13.1 Family A G protein-coupled receptor-like
View Download 0.309 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.309 a.64.1 Saposin
View Download 0.307 a.156.1 S13-like H2TH domain
View Download 0.305 a.4.1 Homeodomain-like
View Download 0.305 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.303 a.64.1 Saposin
View Download 0.299 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.298 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.298 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.297 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.293 a.4.5 "Winged helix" DNA-binding domain
View Download 0.293 a.4.5 "Winged helix" DNA-binding domain
View Download 0.290 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.288 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.286 d.58.48 MTH1187-like
View Download 0.285 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.284 a.6.1 Putative DNA-binding domain
View Download 0.281 a.4.1 Homeodomain-like
View Download 0.280 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.275 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.274 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.267 a.4.5 "Winged helix" DNA-binding domain
View Download 0.266 a.144.1 PABC (PABP) domain
View Download 0.266 a.29.4 RecG, N-terminal domain
View Download 0.265 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.263 a.112.1 Description not found.
View Download 0.263 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.261 a.4.5 "Winged helix" DNA-binding domain
View Download 0.259 a.4.5 "Winged helix" DNA-binding domain
View Download 0.258 a.24.17 Group V grass pollen allergen
View Download 0.257 a.140.2 SAP domain
View Download 0.255 a.4.8 Ribosomal protein S18
View Download 0.252 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.252 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.251 f.30.1 Photosystem I reaction center subunit X, PsaK
View Download 0.248 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.248 a.112.1 Description not found.
View Download 0.248 f.17.1 F1F0 ATP synthase subunit C
View Download 0.246 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.243 f.17.1 F1F0 ATP synthase subunit C
View Download 0.242 a.77.1 DEATH domain
View Download 0.242 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.242 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.241 a.112.1 Description not found.
View Download 0.239 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.237 a.77.1 DEATH domain
View Download 0.237 a.140.3 Rho termination factor, N-terminal domain
View Download 0.236 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.235 a.6.1 Putative DNA-binding domain
View Download 0.235 a.64.1 Saposin
View Download 0.234 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.233 a.24.17 Group V grass pollen allergen
View Download 0.233 a.24.17 Group V grass pollen allergen
View Download 0.231 a.64.1 Saposin
View Download 0.230 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.230 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.229 a.144.2 Ribosomal protein L20
View Download 0.227 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.226 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.225 g.57.1 Serine proteinase inhibitor lekti
View Download 0.224 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.221 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.220 a.112.1 Description not found.
View Download 0.219 a.157.1 Skp1 dimerisation domain-like
View Download 0.219 f.15.1 Small-conductance potassium channel
View Download 0.219 a.64.1 Saposin
View Download 0.218 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.217 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.215 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.215 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.211 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.210 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.208 a.156.1 S13-like H2TH domain
View Download 0.208 a.64.1 Saposin
View Download 0.206 a.2.3 Chaperone J-domain
View Download 0.205 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.203 a.5.6 Hypothetical protein MTH1615
View Download 0.201 a.144.1 PABC (PABP) domain
View Download 0.200 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain

Predicted functions:

Term Confidence Notes
catalytic activity 0.531942688196759 bayes_pls_golite062009
hydrolase activity 0.464324757821572 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [492-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGKVHLVGHS LGSMILFDIL SKQKKYELEF QVDNLFFIGS PIGLLKLIQR TKIGDRPEFP  60
   61 NDLERKLTVQ RPQCKDIYNV YHVCDPISYR MEPLVSKEMA HYEQTYLPHC SEAYGLTSKV 120
  121 LEFGENIWKD LPGTDENNLQ SKKTSPEKKE VKLSENLTRM LTGLNYTGRL DYAMSPSLLE 180
  181 VDFISAIKSH VSYFEEPDIA AFILKEILSK HENASEIYVK RKTG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 89.568636
Match: PF02862
Description: DDHD domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle