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View Structure Prediction Details

Protein: SGT2
Organism: Saccharomyces cerevisiae
Length: 346 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGT2.

Description E-value Query
Range
Subject
Range
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
2.0E-61 [2..328] [137..495]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
5.0E-61 [2..328] [108..466]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
1.0E-60 [2..328] [98..456]
OGT - O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco...
gi|123993895, gi... - gi|224487755|dbj|BAH24112.1| O-linked N-acetylglucosamine (GlcNAc) transferase [synthetic construct]...
1.0E-60 [2..328] [98..456]
ogt-1 - status:Confirmed UniProt:O18158 protein_id:AAA62535.2
2.0E-57 [2..328] [212..570]
gi|17231265, gi|... - gi|17231265|ref|NP_487813.1| serine/threonine kinase [Nostoc sp. PCC 7120], gi|17132907|dbj|BAB75472...
gi|25533209 - pir||AF2277 serine/threonine kinase [imported] - Nostoc sp. (strain PCC 7120)
2.0E-55 [2..340] [348..707]
SEC_ARATH - Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC OS=Arabidopsis thalian...
7.0E-55 [2..325] [140..495]
gi|7459511 - pir||F69210 conserved hypothetical protein MTH83 - Methanobacterium thermoautotrophicum (strain Delt...
gi|2621120, gi|1... - gi|2621120|gb|AAB84589.1| O-linked GlcNAc transferase [Methanothermobacter thermautotrophicus str. D...
2.0E-50 [2..294] [69..353]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKEEIAA LIVNYFSSIV EKKEISEDGA DSLNVAMDCI SEAFGFEREA VSGILGKSEF  60
   61 K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.672 a.4.1 Homeodomain-like
View Download 0.646 a.4.1 Homeodomain-like
View Download 0.645 a.4.1 Homeodomain-like
View Download 0.626 a.159.2 FF domain
View Download 0.615 a.4.1 Homeodomain-like
View Download 0.603 a.4.1 Homeodomain-like
View Download 0.583 a.159.2 FF domain
View Download 0.556 a.4.1 Homeodomain-like
View Download 0.556 a.4.5 "Winged helix" DNA-binding domain
View Download 0.554 a.4.1 Homeodomain-like
View Download 0.539 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.528 a.112.1 Description not found.
View Download 0.522 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.511 a.112.1 Description not found.
View Download 0.500 d.102.1 Regulatory factor Nef
View Download 0.499 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.497 a.4.1 Homeodomain-like
View Download 0.491 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.491 f.13.1 Family A G protein-coupled receptor-like
View Download 0.490 a.2.7 tRNA-binding arm
View Download 0.488 a.112.1 Description not found.
View Download 0.488 a.4.1 Homeodomain-like
View Download 0.480 a.4.1 Homeodomain-like
View Download 0.476 a.4.1 Homeodomain-like
View Download 0.476 a.4.5 "Winged helix" DNA-binding domain
View Download 0.475 a.4.1 Homeodomain-like
View Download 0.446 f.13.1 Family A G protein-coupled receptor-like
View Download 0.445 a.112.1 Description not found.
View Download 0.440 a.4.5 "Winged helix" DNA-binding domain
View Download 0.436 a.51.1 Cytochrome c oxidase subunit h
View Download 0.432 a.4.1 Homeodomain-like
View Download 0.431 a.4.1 Homeodomain-like
View Download 0.431 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.425 a.4.5 "Winged helix" DNA-binding domain
View Download 0.422 a.4.5 "Winged helix" DNA-binding domain
View Download 0.422 a.3.1 Cytochrome c
View Download 0.418 a.4.5 "Winged helix" DNA-binding domain
View Download 0.418 a.2.7 tRNA-binding arm
View Download 0.413 a.39.1 EF-hand
View Download 0.406 a.112.1 Description not found.
View Download 0.398 a.16.1 S15/NS1 RNA-binding domain
View Download 0.390 a.159.2 FF domain
View Download 0.387 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.381 a.4.1 Homeodomain-like
View Download 0.378 a.60.2 RuvA domain 2-like
View Download 0.372 a.4.1 Homeodomain-like
View Download 0.370 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.369 a.159.2 FF domain
View Download 0.369 a.4.5 "Winged helix" DNA-binding domain
View Download 0.368 a.112.1 Description not found.
View Download 0.365 a.159.2 FF domain
View Download 0.364 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.359 a.4.1 Homeodomain-like
View Download 0.359 a.2.7 tRNA-binding arm
View Download 0.353 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.350 a.112.1 Description not found.
View Download 0.341 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.338 a.4.1 Homeodomain-like
View Download 0.338 a.159.2 FF domain
View Download 0.335 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.333 d.58.49 YajQ-like
View Download 0.332 a.4.1 Homeodomain-like
View Download 0.331 a.4.5 "Winged helix" DNA-binding domain
View Download 0.329 a.159.2 FF domain
View Download 0.323 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.317 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.316 a.2.7 tRNA-binding arm
View Download 0.316 a.2.7 tRNA-binding arm
View Download 0.316 a.112.1 Description not found.
View Download 0.312 a.112.1 Description not found.
View Download 0.306 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.306 a.4.1 Homeodomain-like
View Download 0.304 a.159.2 FF domain
View Download 0.303 a.16.1 S15/NS1 RNA-binding domain
View Download 0.303 d.54.1 Enolase N-terminal domain-like
View Download 0.301 a.4.5 "Winged helix" DNA-binding domain
View Download 0.300 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.300 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.298 d.58.49 YajQ-like
View Download 0.295 a.4.5 "Winged helix" DNA-binding domain
View Download 0.292 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.290 g.63.1 Mollusk pheromone
View Download 0.290 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.287 a.4.1 Homeodomain-like
View Download 0.281 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.281 a.4.5 "Winged helix" DNA-binding domain
View Download 0.280 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.278 a.17.1 p8-MTCP1
View Download 0.277 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.276 f.15.1 Small-conductance potassium channel
View Download 0.274 a.4.1 Homeodomain-like
View Download 0.272 a.112.1 Description not found.
View Download 0.272 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.272 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.270 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.268 a.4.5 "Winged helix" DNA-binding domain
View Download 0.266 a.159.2 FF domain
View Download 0.266 d.58.49 YajQ-like
View Download 0.264 a.4.1 Homeodomain-like
View Download 0.263 a.65.1 Annexin
View Download 0.261 a.36.1 Signal peptide-binding domain
View Download 0.260 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.260 a.4.1 Homeodomain-like
View Download 0.260 a.4.5 "Winged helix" DNA-binding domain
View Download 0.259 a.60.11 Hypothetical protein YjbJ
View Download 0.257 a.4.5 "Winged helix" DNA-binding domain
View Download 0.255 a.16.1 S15/NS1 RNA-binding domain
View Download 0.254 d.52.1 Alpha-lytic protease prodomain
View Download 0.251 g.63.1 Mollusk pheromone
View Download 0.246 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.244 a.65.1 Annexin
View Download 0.244 a.2.3 Chaperone J-domain
View Download 0.241 d.58.49 YajQ-like
View Download 0.239 d.52.1 Alpha-lytic protease prodomain
View Download 0.238 a.28.1 ACP-like
View Download 0.237 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.236 a.4.1 Homeodomain-like
View Download 0.235 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.235 d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.234 a.4.1 Homeodomain-like
View Download 0.233 a.112.1 Description not found.
View Download 0.233 d.58.17 Metal-binding domain
View Download 0.229 d.58.49 YajQ-like
View Download 0.229 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.229 a.161.1 beta-catenin-interacting protein ICAT
View Download 0.227 a.7.6 Ribosomal protein S20
View Download 0.226 a.159.2 FF domain
View Download 0.226 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.225 a.60.11 Hypothetical protein YjbJ
View Download 0.225 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.223 a.112.1 Description not found.
View Download 0.222 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.221 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.216 a.3.1 Cytochrome c
View Download 0.216 a.4.5 "Winged helix" DNA-binding domain
View Download 0.216 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.215 a.26.1 4-helical cytokines
View Download 0.215 d.58.4 Dimeric alpha+beta barrel
View Download 0.214 a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 a.51.1 Cytochrome c oxidase subunit h
View Download 0.214 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.214 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.212 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.212 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.210 a.112.1 Description not found.
View Download 0.209 a.3.1 Cytochrome c
View Download 0.207 d.58.49 YajQ-like
View Download 0.206 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.206 a.39.1 EF-hand
View Download 0.206 a.16.1 S15/NS1 RNA-binding domain
View Download 0.205 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.205 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.205 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.204 a.112.1 Description not found.
View Download 0.204 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.202 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.202 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.201 d.58.49 YajQ-like

Predicted Domain #2
Region A:
Residues: [62-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQHLADILNS ASRVPESNKK DDAENVEINI PEDDAETKAK AEDLKMQGNK AMANKDYELA  60
   61 INKYTEAIKV LPTNAIYYAN RAAAHSSLKE YDQAVKDAES AISIDPSYFR GYSRLGFAKY 120
  121 AQGKPEEALE AYKKVLDIEG DNATEAMKRD YESAKKKVEQ SLNLEKTVPE QSRDADVDAS 180
  181 QGASAGGLPD LGSLLGGGLG GLMNNPQLMQ AAQKMMSNPG AMQNIQKMMQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 173.9691
Match: 1a17__
Description: Protein phosphatase 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.12690485191789 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
heat shock protein binding 1.35268080101836 bayes_pls_golite062009
unfolded protein binding 1.03065657981002 bayes_pls_golite062009
nucleic acid binding 0.41706917101675 bayes_pls_golite062009
hydrolase activity 0.252678932946087 bayes_pls_golite062009
transcription regulator activity 0.194719472400022 bayes_pls_golite062009
DNA binding 0.17736976899009 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [292-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPSIRQMAEG FASGGGTPNL SDLMNNPALR NMAGNLFGGA GAQSTDETPD NENKQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.440 d.68.7 R3H domain
View Download 0.537 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.352 g.63.1 Mollusk pheromone
View Download 0.343 d.68.7 R3H domain
View Download 0.312 d.68.7 R3H domain
View Download 0.309 d.68.7 R3H domain
View Download 0.303 d.58.17 Metal-binding domain
View Download 0.282 d.68.7 R3H domain
View Download 0.259 d.68.3 SirA-like
View Download 0.254 a.64.2 Bacteriocin AS-48
View Download 0.238 d.68.7 R3H domain
View Download 0.230 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.227 a.4.1 Homeodomain-like
View Download 0.225 a.4.5 "Winged helix" DNA-binding domain
View Download 0.223 d.68.7 R3H domain
View Download 0.223 d.68.7 R3H domain
View Download 0.223 d.68.7 R3H domain
View Download 0.216 d.68.3 SirA-like
View Download 0.216 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.213 a.180.1 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
View Download 0.212 d.68.7 R3H domain
View Download 0.207 d.68.5 C-terminal domain of ProRS
View Download 0.204 d.68.5 C-terminal domain of ProRS


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle