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View Structure Prediction Details

Protein: PRE6
Organism: Saccharomyces cerevisiae
Length: 254 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRE6.

Description E-value Query
Range		 Subject
Range
PSA7_CICAR - Proteasome subunit alpha type-7 OS=Cicer arietinum GN=PAD1 PE=2 SV=1
 4.0E-82 [1..233] [1..228]
PSA7_SOLLC - Proteasome subunit alpha type-7 OS=Solanum lycopersicum GN=PAD1 PE=2 SV=1
 9.0E-82 [1..233] [1..228]
PSA7L_MOUSE - Proteasome subunit alpha type-7-like OS=Mus musculus GN=Psma8 PE=1 SV=1
 3.0E-81 [2..252] [3..249]
gi|14488821, gi|... - gi|14488821|pdb|1FNT|Q Chain Q, Crystal Structure Of The 20s Proteasome From Yeast In Complex With T...
 4.0E-80 [1..243] [1..243]
gi|2511580, gi|2... - gi|2511582|emb|CAA73623.1| multicatalytic endopeptidase [Arabidopsis thaliana], gi|2511580|emb|CAA73...
 7.0E-80 [1..239] [1..235]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 1.0E-79 [1..233] [1..228]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 7.0E-79 [2..233] [8..234]

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Predicted Domain #1
Region A:
Residues: [1-254] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGYDRALSI FSPDGHIFQV EYALEAVKRG TCAVGVKGKN CVVLGCERRS TLKLQDTRIT  60
   61 PSKVSKIDSH VVLSFSGLNA DSRILIEKAR VEAQSHRLTL EDPVTVEYLT RYVAGVQQRY 120
  121 TQSGGVRPFG VSTLIAGFDP RDDEPKLYQT EPSGIYSSWS AQTIGRNSKT VREFLEKNYD 180
  181 RKEPPATVEE CVKLTVRSLL EVVQTGAKNI EITVVKPDSD IVALSSEEIN QYVTQIEQEK 240
  241 QEQQEQDKKK KSNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1391.0
Match: 1g0uC_
Description: Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
binding 1.75265921676176 bayes_pls_golite062009
nucleic acid binding 1.39216781236247 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle