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View Structure Prediction Details

Protein: RRG9
Organism: Saccharomyces cerevisiae
Length: 214 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRG9.

Description E-value Query
Range
Subject
Range
RRG9_YEAS2 - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain JAY291)...
RRG9_YEAS6 - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain AWRI163...
RRG9_YEAS1 - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain RM11-1a...
RRG9_YEAST - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 20...
RRG9_YEAS8 - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain Lalvin ...
RRG9_YEAS7 - Required for respiratory growth protein 9, mitochondrial OS=Saccharomyces cerevisiae (strain YJM789)...
RRG9 - Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the au...
1.0E-98 [1..214] [1..214]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-30 [59..148] [195..284]
gi|13278462 - gi|13278462|gb|AAH04034.1| Ngrn protein [Mus musculus]
3.0E-27 [66..140] [6..80]
NGRN - neugrin, neurite outgrowth associated
2.0E-25 [70..140] [1..71]
CG4553-PA - This gene is referred to in FlyBase by the symbol Dmel\CG4553 (CG4553, FBgn0039336). It is a protein...
1.0E-17 [78..139] [94..157]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILRIACRS FHCLRCGPLL NENRGWSSKK IIKLVNKSSL SNKEFTEKVR DGTKDIPEWK  60
   61 KQKMAVRKKL QGQRWNPPKK ISQEQMEALR LLKFNFPELT ASDLADRFKI SPEAVRRILK 120
  121 SNWKRTDEEN NNTYERWKRR GERIKEMY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.251 0.035 mitochondrion organization a.74.1 Cyclin-like
View Download 0.253 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.52037235769064 bayes_pls_golite062009
nucleic acid binding 3.26601886211701 bayes_pls_golite062009
DNA binding 3.24659040730132 bayes_pls_golite062009
transcription factor activity 2.70611942641509 bayes_pls_golite062009
binding 1.78064857180719 bayes_pls_golite062009
sequence-specific DNA binding 1.51287971227547 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.34461031960924 bayes_pls_golite062009
transcription repressor activity 1.02090023542008 bayes_pls_golite062009
transcription activator activity 0.9113397633272 bayes_pls_golite062009
catalytic activity 0.794231598246996 bayes_pls_golite062009
protein binding 0.64696728529788 bayes_pls_golite062009
transcription factor binding 0.525225093153448 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.134558516082252 bayes_pls_golite062009
chromatin binding 0.0850288412922495 bayes_pls_golite062009
transcription cofactor activity 0.043605800048317 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [149-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRKEDADFVS NQIVTSRKII LGSNSNSPEL IARNVRTFKP FKPNNSTPEK KNTNKLYILK  60
   61 HLGSKQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.482 a.4.1 Homeodomain-like
View Download 0.356 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.482 a.4.1 Homeodomain-like
View Download 0.407 f.14.1 Voltage-gated potassium channels
View Download 0.417 a.144.1 PABC (PABP) domain
View Download 0.356 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.407 f.14.1 Voltage-gated potassium channels
View Download 0.417 a.144.1 PABC (PABP) domain
View Download 0.400 a.112.1 Description not found.
View Download 0.400 a.112.1 Description not found.
View Download 0.323 a.21.1 HMG-box
View Download 0.295 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.289 a.4.5 "Winged helix" DNA-binding domain
View Download 0.251 a.28.1 ACP-like
View Download 0.246 a.3.1 Cytochrome c
View Download 0.244 a.2.3 Chaperone J-domain
View Download 0.242 a.112.1 Description not found.
View Download 0.240 a.3.1 Cytochrome c
View Download 0.230 f.14.1 Voltage-gated potassium channels
View Download 0.229 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.226 a.4.5 "Winged helix" DNA-binding domain
View Download 0.221 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.207 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.200 a.28.2 Colicin E immunity proteins


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