YRC Public Data Repository - Protein Structure Prediction

Protein:	PGA2
Organism:	Saccharomyces cerevisiae
Length:	129 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGA2.

Description	E-value	Query Range	Subject Range
gi\|190409135 - gi\|190409135\|gb\|EDV12400.1\| hypothetical protein SCRG_03283 [Saccharomyces cerevisiae RM11-1a] PGA2_YEAST - Processing of GAS1 and ALP protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PGA... gi\|151944388 - gi\|151944388\|gb\|EDN62666.1\| processing of gas1p and alp [Saccharomyces cerevisiae YJM789] PGA2 - Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-f...	3.0E-46	[1..129]	[1..129]
PGA2_SCHPO - PGA2-homolog C27.01c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC27.01c PE=1 SV=1 SPBC27.01c - secretory pathway protein Pga2	4.0E-29	[16..129]	[9..132]
gi\|1236274 - gi\|1236274\|dbj\|BAA12198.1\| unnamed protein product [Schizosaccharomyces pombe]	1.0E-26	[16..117]	[9..115]
gi\|85102566 - gi\|85102566\|ref\|XP_961357.1\| hypothetical protein NCU03630 [Neurospora crassa OR74A] gi\|32404638, gi\|... - gi\|32404638\|ref\|XP_322932.1\| hypothetical protein [Neurospora crassa], gi\|28922901\|gb\|EAA32121.1\| pr...	0.001	[18..95]	[25..117]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVAETWVD TWMAKLVNYD YKHFIRLVII VGGYLLLRNI ASRELAKKQL AAQVEKDKRD  60
   61 KEEKRSKDLI DKPDDAATAE TTSFGWGKKT RRRVKRQQEL FENALEEAKR RNQGLDPDSD 120
  121 ADIEELLEE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pcons
Confidence:	1.55
Match:	1jgsA
Description:	Multiple antibiotic resistance repressor, MarR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.92638462203672	bayes_pls_golite062009
transcription regulator activity	2.22253996678636	bayes_pls_golite062009
nucleic acid binding	2.14288680048889	bayes_pls_golite062009
DNA binding	2.10600827813244	bayes_pls_golite062009
transcription factor activity	1.32901697252559	bayes_pls_golite062009
protein binding	1.2080702238979	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.436849299068334	bayes_pls_golite062009
structural molecule activity	0.241691756012358	bayes_pls_golite062009
sequence-specific DNA binding	0.215472749582216	bayes_pls_golite062009
structural constituent of ribosome	0.145583411541476	bayes_pls_golite062009
transcription activator activity	0.0101820413115041	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: