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View Structure Prediction Details

Protein: OCA2
Organism: Saccharomyces cerevisiae
Length: 197 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCA2.

Description E-value Query
Range		 Subject
Range
OCA2 - Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluoresc...
OCA2_YEAST - Tyrosine-protein phosphatase-like protein OCA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
 9.0E-44 [1..197] [1..197]
vhp-1 - status:Partially_confirmed UniProt:Q10038 protein_id:AAK68300.1
 4.0E-38 [12..196] [125..297]
gi|18376661, gi|... - gi|239047441|ref|NP_001154802.1| slingshot 1 isoform 2 [Homo sapiens], gi|18376661|dbj|BAB84115.1| h...
 2.0E-33 [13..192] [310..481]
Y1500_ARATH - Probable tyrosine-protein phosphatase At1g05000 OS=Arabidopsis thaliana GN=At1g05000 PE=1 SV=1
 8.0E-32 [1..152] [51..199]
DUS1A_XENLA - Dual specificity protein phosphatase 1-A OS=Xenopus laevis GN=dusp1-a PE=1 SV=1
 3.0E-31 [10..165] [174..317]
gi|409977 - gi|409977|gb|AAB27882.1| nontransmembrane protein tyrosine phosphatase; ERP [Mus sp.]
DUS1_MOUSE - Dual specificity protein phosphatase 1 OS=Mus musculus GN=Dusp1 PE=1 SV=1
 7.0E-31 [10..169] [172..317]

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Predicted Domain #1
Region A:
Residues: [1-197] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYIPPLNFS PVVSTDVSLY RSGYPMPLNY SFIKHQLHLK TIIYIGDKDR PLEEYQSFLE  60
   61 SEKIKYYHIF MDSSRDEGIQ ERMNQVLHLV LDVRNYPILV HSNKGKHRVG VVVGIIRKLL 120
  121 QGWSTAGICQ EYGLFSGGMK DGVDLEFITM FETNLKIPRN VIPGFAKHCL YLNELEAAEG 180
  181 SDDESGSESI LTAKQPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.154902
Match: 1mkp__
Description: Mapk phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.30669036331612 bayes_pls_golite062009
phosphatase activity 6.6585143972081 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.44546424348532 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.56007278295923 bayes_pls_golite062009
protein tyrosine phosphatase activity 5.3097342170423 bayes_pls_golite062009
hydrolase activity 4.08088661270715 bayes_pls_golite062009
transmembrane receptor protein phosphatase activity 2.94635032478625 bayes_pls_golite062009
transmembrane receptor protein tyrosine phosphatase activity 2.94635032478625 bayes_pls_golite062009
protein tyrosine/serine/threonine phosphatase activity 2.77531895423367 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.95004535887255 bayes_pls_golite062009
binding 1.94343241290871 bayes_pls_golite062009
protein binding 1.2114562222518 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 1.1200449509328 bayes_pls_golite062009
catalytic activity 1.06283028154109 bayes_pls_golite062009
lipid phosphatase activity 1.05085928819585 bayes_pls_golite062009
nucleic acid binding 0.766259791679226 bayes_pls_golite062009
DNA binding 0.744259483210066 bayes_pls_golite062009
non-membrane spanning protein tyrosine phosphatase activity 0.724257798127697 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0776644624761281 bayes_pls_golite062009
kinase activity 0.0715870881653981 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle